| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.12524 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.109189 |
| GOLGA4 | golgin A4 | 0.0972782 |
| PRELID2 | PRELI domain containing 2 | 0.0785901 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0768913 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0680195 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0679746 |
| RACK1 | receptor for activated C kinase 1 | 0.0672703 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0654955 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0597369 |
| TMF1 | TATA element modulatory factor 1 | 0.0521293 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.050987 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0492592 |
| RBM39 | RNA binding motif protein 39 | 0.0481148 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0473226 |
| ZNF638 | zinc finger protein 638 | 0.0464965 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0459867 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0454106 |
| RPL3 | ribosomal protein L3 | 0.0437305 |
| RAD51B | RAD51 paralog B | 0.0432816 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0432635 |
| FNDC3B | fibronectin type III domain containing 3B | 0.043142 |
| GOLGA2 | golgin A2 | 0.0426741 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0423176 |
| DSPP | dentin sialophosphoprotein | 0.0417061 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0415483 |
| HDLBP | high density lipoprotein binding protein | 0.0397733 |
| OGA | O-GlcNAcase | 0.0397394 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0397377 |
| YEATS2 | YEATS domain containing 2 | 0.0385719 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0384814 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0383138 |
| SQSTM1 | sequestosome 1 | 0.0381988 |
| NUP58 | nucleoporin 58 | 0.0375234 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0366584 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0363733 |
| TXNRD1 | thioredoxin reductase 1 | 0.0362157 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0360122 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0357114 |
| SCFD1 | sec1 family domain containing 1 | 0.035421 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0353771 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0347822 |
| HYOU1 | hypoxia up-regulated 1 | 0.03475 |
| HELZ | helicase with zinc finger | 0.0346899 |
| YME1L1 | YME1-like 1 ATPase | 0.0345925 |
| CALR | calreticulin | 0.0344354 |
| GOLGB1 | golgin B1 | 0.0342825 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0341822 |
| USP37 | ubiquitin specific peptidase 37 | 0.0335169 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0329742 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0327623 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0325051 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0322344 |
| INSIG2 | insulin induced gene 2 | 0.0319134 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0314887 |
| PLEC | plectin | 0.0314684 |
| GOLGA3 | golgin A3 | 0.0312224 |
| KIAA1217 | KIAA1217 | 0.0312053 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0311194 |
| SRP54 | signal recognition particle 54kDa | 0.0309301 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0304991 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0302537 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0301904 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0300942 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0299111 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0294724 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0292505 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0289411 |
| CANX | calnexin | 0.0287407 |
| NBAS | neuroblastoma amplified sequence | 0.0286612 |
| RPL23 | ribosomal protein L23 | 0.0280907 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0276681 |
| ZNF652 | zinc finger protein 652 | 0.0276597 |
| COG5 | component of oligomeric golgi complex 5 | 0.0276319 |
| TMEM41B | transmembrane protein 41B | 0.0275303 |
| ZNF292 | zinc finger protein 292 | 0.0273111 |
| SON | SON DNA binding protein | 0.0270053 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0266928 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0265623 |
| PAPOLA | poly(A) polymerase alpha | 0.0265136 |
| SEC24D | SEC24 family member D | 0.0264361 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0262094 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0261799 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0259772 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0258477 |
| ATM | ATM serine/threonine kinase | 0.0255342 |
| SUCO | SUN domain containing ossification factor | 0.0253571 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0251235 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0251176 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0249339 |
| PTEN | phosphatase and tensin homolog | 0.0249338 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0248824 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0248628 |
| METTL15 | methyltransferase like 15 | 0.024807 |
| USO1 | USO1 vesicle transport factor | 0.0245847 |
| RPL26 | ribosomal protein L26 | 0.0245772 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0244011 |
| PGM3 | phosphoglucomutase 3 | 0.0243232 |
| SPAG9 | sperm associated antigen 9 | 0.0242523 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0241635 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.225409 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.187054 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.154677 |
| FAT1 | FAT atypical cadherin 1 | -0.115352 |
| TMSB10 | thymosin beta 10 | -0.0831583 |
| AHNAK | AHNAK nucleoprotein | -0.0667607 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.064622 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0566638 |
| PKM | pyruvate kinase, muscle | -0.0565554 |
| TUBA1B | tubulin, alpha 1b | -0.0497521 |
| POTEF | POTE ankyrin domain family, member F | -0.0480985 |
| MT2A | metallothionein 2A | -0.0466372 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0454871 |
| TPM4 | tropomyosin 4 | -0.0452863 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0429151 |
| S100A10 | S100 calcium binding protein A10 | -0.0409384 |
| ACTG1 | actin gamma 1 | -0.0406341 |
| EGR1 | early growth response 1 | -0.0400965 |
| SERINC5 | serine incorporator 5 | -0.0379308 |
| RPS6 | ribosomal protein S6 | -0.0325443 |
| ENO1 | enolase 1, (alpha) | -0.032206 |
| MKI67 | marker of proliferation Ki-67 | -0.031247 |
| HMGA1 | high mobility group AT-hook 1 | -0.0304587 |
| RPL35A | ribosomal protein L35a | -0.0295969 |
| CDCP1 | CUB domain containing protein 1 | -0.0294071 |
| ASPH | aspartate beta-hydroxylase | -0.0283516 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0281291 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0279678 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0279479 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0279362 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0268762 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0262856 |
| CCND1 | cyclin D1 | -0.0261862 |
| RPS27A | ribosomal protein S27a | -0.0261136 |
| HMGA2 | high mobility group AT-hook 2 | -0.0259851 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0255655 |
| KRT18 | keratin 18, type I | -0.0252362 |
| HMGB1 | high mobility group box 1 | -0.0243655 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0242548 |
| PERP | PERP, TP53 apoptosis effector | -0.0241042 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0238743 |
| CADPS | Ca++-dependent secretion activator | -0.0235159 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0233162 |
| HELLS | helicase, lymphoid-specific | -0.0227649 |
| RPS24 | ribosomal protein S24 | -0.0226852 |
| KPNB1 | karyopherin (importin) beta 1 | -0.022341 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0219552 |
| HLA-B | major histocompatibility complex, class I, B | -0.0219178 |
| RPLP0 | ribosomal protein, large, P0 | -0.0216815 |
| DSG2 | desmoglein 2 | -0.0214919 |
| WWOX | WW domain containing oxidoreductase | -0.0212002 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0211627 |
| S100A9 | S100 calcium binding protein A9 | -0.0211264 |
| RPL38 | ribosomal protein L38 | -0.0208683 |
| S100A6 | S100 calcium binding protein A6 | -0.0206855 |
| RRM2 | ribonucleotide reductase M2 | -0.0203039 |
| VDAC1 | voltage-dependent anion channel 1 | -0.020216 |
| FRMD5 | FERM domain containing 5 | -0.0201895 |
| RPS8 | ribosomal protein S8 | -0.0201567 |
| RPL34 | ribosomal protein L34 | -0.020049 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0198748 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0198532 |
| H1-0 | H1.0 linker histone | -0.0198312 |
| PRDX2 | peroxiredoxin 2 | -0.0197686 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0194402 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0190231 |
| MORC4 | MORC family CW-type zinc finger 4 | -0.0189536 |
| EGFR | epidermal growth factor receptor | -0.0188543 |
| RPL31 | ribosomal protein L31 | -0.0188366 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.0184701 |
| RPLP2 | ribosomal protein, large, P2 | -0.0184016 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0183517 |
| STMN1 | stathmin 1 | -0.0181367 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0180116 |
| RAN | RAN, member RAS oncogene family | -0.0179466 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0178142 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0174397 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0173972 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0173429 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0170328 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0169685 |
| MSI2 | musashi RNA-binding protein 2 | -0.0168552 |
| ZNRF3 | zinc and ring finger 3 | -0.0168022 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0167976 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0167134 |
| RPS21 | ribosomal protein S21 | -0.0165834 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0163929 |
| ITGB4 | integrin, beta 4 | -0.0163161 |
| RPS17 | ribosomal protein S17 | -0.0162907 |
| RPL32 | ribosomal protein L32 | -0.016246 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0161594 |
| HOMER1 | homer scaffolding protein 1 | -0.0160369 |
| IER3 | immediate early response 3 | -0.0160227 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0159957 |
| RPS15 | ribosomal protein S15 | -0.015974 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0159736 |
| RPS3 | ribosomal protein S3 | -0.0159339 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0157792 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0155453 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0154171 |
