| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.336518 |
| NDRG1 | N-myc downstream regulated 1 | 0.136909 |
| RACK1 | receptor for activated C kinase 1 | 0.0725713 |
| RPL35A | ribosomal protein L35a | 0.0369049 |
| VEGFA | vascular endothelial growth factor A | 0.0358281 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0313498 |
| YBX1 | Y box binding protein 1 | 0.0306494 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0286711 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0248637 |
| RPS6 | ribosomal protein S6 | 0.0236481 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0225933 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0215832 |
| FLNA | filamin A, alpha | 0.0211118 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0186872 |
| RPL30 | ribosomal protein L30 | 0.0186287 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0182765 |
| GOLGA4 | golgin A4 | 0.0181744 |
| RPL7 | ribosomal protein L7 | 0.0177807 |
| B2M | beta-2-microglobulin | 0.0176957 |
| RPL3 | ribosomal protein L3 | 0.0174247 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0171009 |
| RPL11 | ribosomal protein L11 | 0.0165577 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0160477 |
| RPL13A | ribosomal protein L13a | 0.0157306 |
| FTL | ferritin, light polypeptide | 0.0156008 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0155542 |
| ZNF292 | zinc finger protein 292 | 0.0153149 |
| CADM1 | cell adhesion molecule 1 | 0.0152022 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0151632 |
| CAVIN1 | caveolae associated protein 1 | 0.0149433 |
| ARRDC3 | arrestin domain containing 3 | 0.0146804 |
| RPS2 | ribosomal protein S2 | 0.0143871 |
| RPS12 | ribosomal protein S12 | 0.014349 |
| RPS8 | ribosomal protein S8 | 0.0142151 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0141892 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0141357 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | 0.0138612 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0138099 |
| CABIN1 | calcineurin binding protein 1 | 0.0136428 |
| NAV2 | neuron navigator 2 | 0.0133927 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0133583 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.013291 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0132038 |
| STC2 | stanniocalcin 2 | 0.0130875 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0130861 |
| CCNL1 | cyclin L1 | 0.0129349 |
| HYOU1 | hypoxia up-regulated 1 | 0.0129317 |
| ADM | adrenomedullin | 0.0128901 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0124974 |
| SERF2 | small EDRK-rich factor 2 | 0.0124287 |
| RPL12 | ribosomal protein L12 | 0.0123087 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0122431 |
| RPS19 | ribosomal protein S19 | 0.0121183 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0117606 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0117523 |
| ATP13A3 | ATPase type 13A3 | 0.0113863 |
| RPL26 | ribosomal protein L26 | 0.0112946 |
| CDC27 | cell division cycle 27 | 0.0112581 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0111669 |
| RPS4X | ribosomal protein S4, X-linked | 0.0110998 |
| RPL37 | ribosomal protein L37 | 0.0109064 |
| FMNL2 | formin-like 2 | 0.0108791 |
| SPAG9 | sperm associated antigen 9 | 0.0108627 |
| NCKAP1 | NCK-associated protein 1 | 0.0107608 |
| RPL23 | ribosomal protein L23 | 0.0106852 |
| RPL37A | ribosomal protein L37a | 0.0106747 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0105996 |
| POSTN | periostin, osteoblast specific factor | 0.0105498 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0104739 |
| PDE10A | phosphodiesterase 10A | 0.0104534 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0104331 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0104287 |
| RPS15A | ribosomal protein S15a | 0.0103919 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0103405 |
| PDE8A | phosphodiesterase 8A | 0.0102541 |
| FAM13A | family with sequence similarity 13, member A | 0.0101974 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0101909 |
| RPL34 | ribosomal protein L34 | 0.010166 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0101597 |
| DSPP | dentin sialophosphoprotein | 0.0100956 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00985424 |
| TPR | translocated promoter region, nuclear basket protein | 0.00979677 |
| FNBP1L | formin binding protein 1-like | 0.00972214 |
| RNF145 | ring finger protein 145 | 0.00966315 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | 0.00965456 |
| RLF | rearranged L-myc fusion | 0.00954157 |
| OPTN | optineurin | 0.00949149 |
| FOSL1 | FOS-like antigen 1 | 0.00943349 |
| RPLP1 | ribosomal protein, large, P1 | 0.00942787 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00937256 |
| MKI67 | marker of proliferation Ki-67 | 0.00931937 |
| MALT1 | MALT1 paracaspase | 0.00912954 |
| BUB3 | BUB3 mitotic checkpoint protein | 0.00911943 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00908805 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.00906226 |
| CCDC88A | coiled-coil domain containing 88A | 0.00906112 |
| ATG3 | autophagy related 3 | 0.00905093 |
| KLHDC10 | kelch domain containing 10 | 0.00905092 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | 0.00904962 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.00902086 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.233169 |
| COL1A1 | collagen, type I, alpha 1 | -0.176836 |
| VIM | vimentin | -0.148883 |
| CD44 | CD44 molecule (Indian blood group) | -0.106874 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.106606 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.100168 |
| UBC | ubiquitin C | -0.0973407 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.086461 |
| ENO1 | enolase 1, (alpha) | -0.0817136 |
| ASPH | aspartate beta-hydroxylase | -0.0799761 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0696838 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0696521 |
| EXT1 | exostosin glycosyltransferase 1 | -0.068894 |
| COL1A2 | collagen, type I, alpha 2 | -0.0681647 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0662894 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0656888 |
| AHNAK | AHNAK nucleoprotein | -0.0632625 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.058949 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0582064 |
| FBN1 | fibrillin 1 | -0.0562883 |
| CDH13 | cadherin 13 | -0.051301 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0507886 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0455874 |
| LDHA | lactate dehydrogenase A | -0.0438376 |
| FN1 | fibronectin 1 | -0.042562 |
| INHBA | inhibin, beta A | -0.0411676 |
| IL6ST | interleukin 6 signal transducer | -0.040598 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0405498 |
| PKM | pyruvate kinase, muscle | -0.0403224 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0400768 |
| CALU | calumenin | -0.0398848 |
| COL5A1 | collagen, type V, alpha 1 | -0.0394604 |
| GLIS3 | GLIS family zinc finger 3 | -0.0392408 |
| HMGA2 | high mobility group AT-hook 2 | -0.0370422 |
| CLIC4 | chloride intracellular channel 4 | -0.0321685 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0315352 |
| RPS27A | ribosomal protein S27a | -0.0308498 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0307898 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0304541 |
| CANX | calnexin | -0.0298245 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0293109 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0287921 |
| IL6 | interleukin 6 | -0.0281681 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0280064 |
| IER3 | immediate early response 3 | -0.0279285 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0271518 |
| MAP1B | microtubule-associated protein 1B | -0.0271516 |
| NAV1 | neuron navigator 1 | -0.0265336 |
| CALR | calreticulin | -0.0263229 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0259839 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0259438 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0259196 |
| OSMR | oncostatin M receptor | -0.025301 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0249668 |
| ATXN1 | ataxin 1 | -0.0244507 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0241017 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0239402 |
| CALD1 | caldesmon 1 | -0.0236821 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0234473 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0228587 |
| HLA-B | major histocompatibility complex, class I, B | -0.0228237 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0227137 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.022451 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0223511 |
| TMSB10 | thymosin beta 10 | -0.0218954 |
| NOTCH2 | notch 2 | -0.021809 |
| COL3A1 | collagen, type III, alpha 1 | -0.0216678 |
| VCL | vinculin | -0.0211577 |
| NRP1 | neuropilin 1 | -0.0204365 |
| JUN | jun proto-oncogene | -0.0203538 |
| FAT1 | FAT atypical cadherin 1 | -0.0203246 |
| CNTN5 | contactin 5 | -0.0198182 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0192834 |
| VMP1 | vacuole membrane protein 1 | -0.0190745 |
| RIGI | RNA sensor RIG-I | -0.0190104 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0188986 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0187537 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0187222 |
| MT1X | metallothionein 1X | -0.0184679 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.018455 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.018391 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0182825 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0181676 |
| ZNF644 | zinc finger protein 644 | -0.0180889 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0180821 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0177334 |
| PTK2 | protein tyrosine kinase 2 | -0.0177301 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0175101 |
| APP | amyloid beta (A4) precursor protein | -0.0173834 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0173768 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0172992 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0172376 |
| SMYD3 | SET and MYND domain containing 3 | -0.0167421 |
| SDC2 | syndecan 2 | -0.0167407 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0167122 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.016526 |
| TPM1 | tropomyosin 1 (alpha) | -0.0164716 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0163693 |
| POTEF | POTE ankyrin domain family, member F | -0.0163188 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0159934 |
