| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.0709451 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0577444 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0528046 |
| RACK1 | receptor for activated C kinase 1 | 0.0502653 |
| RBM39 | RNA binding motif protein 39 | 0.0414694 |
| KIAA1217 | KIAA1217 | 0.0404171 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0396971 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0354418 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0339968 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0332694 |
| DSPP | dentin sialophosphoprotein | 0.033246 |
| RPL3 | ribosomal protein L3 | 0.0327577 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0310035 |
| DTNA | dystrobrevin, alpha | 0.029161 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0287744 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0286771 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0285233 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0281695 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0275795 |
| MALT1 | MALT1 paracaspase | 0.0261694 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0259468 |
| PTK2 | protein tyrosine kinase 2 | 0.0258808 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0256929 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0244597 |
| AFDN | afadin, adherens junction formation factor | 0.0244553 |
| ELL | elongation factor RNA polymerase II | 0.0241764 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0241707 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0237152 |
| FRK | fyn-related Src family tyrosine kinase | 0.0237113 |
| RPS12 | ribosomal protein S12 | 0.0226743 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0226081 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0224915 |
| SLK | STE20-like kinase | 0.0220766 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0220555 |
| MATR3 | matrin 3 | 0.0219069 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.0214561 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0212097 |
| ANXA5 | annexin A5 | 0.0210061 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0209251 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0207364 |
| FAM168B | family with sequence similarity 168, member B | 0.0206784 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0206333 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0205423 |
| JAK1 | Janus kinase 1 | 0.0205147 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0202666 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.020022 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0199007 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0197283 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0195845 |
| PARD3 | par-3 family cell polarity regulator | 0.0194382 |
| MYO1B | myosin IB | 0.0191483 |
| ASGR2 | asialoglycoprotein receptor 2 | 0.0190412 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0189288 |
| ARRDC3 | arrestin domain containing 3 | 0.0188892 |
| SEPTIN10 | septin 10 | 0.0187994 |
| PATL1 | protein associated with topoisomerase II homolog 1 (yeast) | 0.0186148 |
| RPL26 | ribosomal protein L26 | 0.0186065 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0183286 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0183155 |
| SPAG9 | sperm associated antigen 9 | 0.0180682 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0179901 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0179009 |
| GSN | gelsolin | 0.0178758 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0178363 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0177942 |
| USP15 | ubiquitin specific peptidase 15 | 0.0177889 |
| ABAT | 4-aminobutyrate aminotransferase | 0.0177211 |
| SPOPL | speckle-type POZ protein-like | 0.0176477 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0175325 |
| IL4R | interleukin 4 receptor | 0.0174333 |
| DENND4A | DENN/MADD domain containing 4A | 0.0173158 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.017152 |
| OGA | O-GlcNAcase | 0.0170638 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0170318 |
| OPTN | optineurin | 0.0169431 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0169296 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0166602 |
| RELL1 | RELT-like 1 | 0.0165818 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0165789 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0165642 |
| TPM3 | tropomyosin 3 | 0.0165473 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0165062 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0164293 |
| UBXN4 | UBX domain protein 4 | 0.0163845 |
| MAPK6 | mitogen-activated protein kinase 6 | 0.0163575 |
| RABGAP1 | RAB GTPase activating protein 1 | 0.0161978 |
| ASPH | aspartate beta-hydroxylase | 0.0161631 |
| HPN | hepsin | 0.0161455 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0161385 |
| EFNA5 | ephrin-A5 | 0.0161273 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0160071 |
| PRELID2 | PRELI domain containing 2 | 0.0159766 |
| HLF | hepatic leukemia factor | 0.0158945 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0157435 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0157424 |
| SZRD1 | SUZ RNA binding domain containing 1 | 0.0157352 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0154362 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0154059 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0153956 |
| SERINC1 | serine incorporator 1 | 0.0153492 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.355025 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.316849 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.142626 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0910274 |
| MT2A | metallothionein 2A | -0.0849289 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0824394 |
| FN1 | fibronectin 1 | -0.0788945 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0767032 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0689537 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0638219 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.063457 |
| GPC6 | glypican 6 | -0.0628634 |
| FTL | ferritin, light polypeptide | -0.0611871 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.059201 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0554672 |
| APOB | apolipoprotein B | -0.049389 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0470644 |
| VCL | vinculin | -0.0463279 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0439275 |
| RPLP1 | ribosomal protein, large, P1 | -0.041808 |
| RPS24 | ribosomal protein S24 | -0.0410548 |
| PTCHD4 | patched domain containing 4 | -0.0397902 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0394674 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0394465 |
| RPLP0 | ribosomal protein, large, P0 | -0.0380297 |
| APOA2 | apolipoprotein A-II | -0.0377481 |
| C3 | complement component 3 | -0.0344521 |
| GPC3 | glypican 3 | -0.0340467 |
| RPS6 | ribosomal protein S6 | -0.0338814 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.0335951 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0334377 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0329891 |
| BCL2L1 | BCL2-like 1 | -0.0326783 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0318185 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0317346 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.031617 |
| TRIM26 | tripartite motif containing 26 | -0.0309112 |
| FAM107B | family with sequence similarity 107, member B | -0.0306139 |
| HMGA1 | high mobility group AT-hook 1 | -0.0305662 |
| RPS29 | ribosomal protein S29 | -0.030491 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0303873 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0296225 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0295599 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0280544 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0278119 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0276733 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0275228 |
| AHSG | alpha-2-HS-glycoprotein | -0.0273131 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0270969 |
| ZNF644 | zinc finger protein 644 | -0.0270439 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0266534 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0265481 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0262867 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0254832 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0253804 |
| TMEM123 | transmembrane protein 123 | -0.0252558 |
| TMSB10 | thymosin beta 10 | -0.0250209 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0246418 |
| TFRC | transferrin receptor | -0.0242864 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.0242447 |
| CCN2 | cellular communication network factor 2 | -0.0242278 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0240982 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0240291 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0239046 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.023787 |
| CMIP | c-Maf inducing protein | -0.0237541 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.023573 |
| ATXN2 | ataxin 2 | -0.0234893 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0231355 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.022143 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0218506 |
| RYBP | RING1 and YY1 binding protein | -0.0217648 |
| STK17A | serine/threonine kinase 17a | -0.0217446 |
| LYZ | lysozyme | -0.0215854 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0213236 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0212167 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.021119 |
| ENAH | enabled homolog (Drosophila) | -0.0210404 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0210171 |
| TXNRD1 | thioredoxin reductase 1 | -0.0210029 |
| CPE | carboxypeptidase E | -0.0208914 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0205454 |
| GNAS | GNAS complex locus | -0.0204448 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.020419 |
| HLA-A | major histocompatibility complex, class I, A | -0.0203965 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0203896 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0202982 |
| RPS27A | ribosomal protein S27a | -0.0202946 |
| RPL12 | ribosomal protein L12 | -0.0202006 |
| A2M | alpha-2-macroglobulin | -0.0201727 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0200971 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.020062 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0199247 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0198576 |
| FRMD5 | FERM domain containing 5 | -0.0198261 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0196899 |
| VMP1 | vacuole membrane protein 1 | -0.019285 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.01915 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0189612 |
| TPM1 | tropomyosin 1 (alpha) | -0.0187183 |
