| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Levobupivacaine (hydrochloride)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.180484 |
| NDRG1 | N-myc downstream regulated 1 | 0.0619142 |
| B2M | beta-2-microglobulin | 0.0520215 |
| TPM3 | tropomyosin 3 | 0.0490844 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0478814 |
| RACK1 | receptor for activated C kinase 1 | 0.0477718 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0427293 |
| VEGFA | vascular endothelial growth factor A | 0.040258 |
| STC2 | stanniocalcin 2 | 0.0401593 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0343053 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0342079 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0337392 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0322686 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0312181 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0303885 |
| FLNA | filamin A, alpha | 0.0293791 |
| NUP58 | nucleoporin 58 | 0.0292809 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0292665 |
| CEP250 | centrosomal protein 250kDa | 0.0282669 |
| OPTN | optineurin | 0.028172 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0279059 |
| CALR | calreticulin | 0.026981 |
| MSN | moesin | 0.0265285 |
| FOSL1 | FOS-like antigen 1 | 0.0256044 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.0244518 |
| RPL3 | ribosomal protein L3 | 0.0236686 |
| ARRDC3 | arrestin domain containing 3 | 0.0234707 |
| SET | SET nuclear proto-oncogene | 0.0233835 |
| RPS12 | ribosomal protein S12 | 0.0230576 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0227328 |
| YBX1 | Y box binding protein 1 | 0.0220512 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0216779 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0216313 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0210426 |
| MCL1 | myeloid cell leukemia 1 | 0.0202537 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0199532 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0198627 |
| FAM120A | family with sequence similarity 120A | 0.0198007 |
| SSRP1 | structure specific recognition protein 1 | 0.0197936 |
| HDGF | hepatoma-derived growth factor | 0.0187004 |
| CENPF | centromere protein F, 350/400kDa | 0.0177608 |
| FNBP4 | formin binding protein 4 | 0.0174587 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0174222 |
| CPAP | centrosome assembly and centriole elongation protein | 0.0174011 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.01695 |
| FAM219A | family with sequence similarity 219, member A | 0.016725 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0163451 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0163172 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0160945 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0159183 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0157945 |
| BRD2 | bromodomain containing 2 | 0.0157881 |
| POTEF | POTE ankyrin domain family, member F | 0.0153662 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0152926 |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 | 0.0151516 |
| TARDBP | TAR DNA binding protein | 0.0151302 |
| GATA2 | GATA binding protein 2 | 0.0148886 |
| HYOU1 | hypoxia up-regulated 1 | 0.01463 |
| PCBP2 | poly(rC) binding protein 2 | 0.0142797 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0142668 |
| PGM3 | phosphoglucomutase 3 | 0.0142566 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0142277 |
| SEPTIN9 | septin 9 | 0.0141973 |
| PLEC | plectin | 0.0140692 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0139845 |
| CCNL1 | cyclin L1 | 0.0137919 |
| ANXA1 | annexin A1 | 0.0137877 |
| SERF2 | small EDRK-rich factor 2 | 0.0137791 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0137741 |
| TMF1 | TATA element modulatory factor 1 | 0.0136914 |
| ATG3 | autophagy related 3 | 0.0135572 |
| L1CAM | L1 cell adhesion molecule | 0.0131282 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.013003 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0127535 |
| RPS15A | ribosomal protein S15a | 0.0127526 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0126891 |
| PNN | pinin, desmosome associated protein | 0.012685 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0126238 |
| DTNA | dystrobrevin, alpha | 0.0125902 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0125355 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0124566 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0123905 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0123298 |
| CBX3 | chromobox homolog 3 | 0.0123086 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0121282 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.012115 |
| PDE10A | phosphodiesterase 10A | 0.0120754 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | 0.0120251 |
| LRRC59 | leucine rich repeat containing 59 | 0.0119939 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0118759 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.011858 |
| GDI1 | GDP dissociation inhibitor 1 | 0.0118261 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0118196 |
| SULF1 | sulfatase 1 | 0.011698 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0115661 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0115388 |
| ZNF141 | zinc finger protein 141 | 0.0115198 |
| RHOA | ras homolog family member A | 0.0114981 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0112385 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0111899 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.210034 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.207496 |
| EXT1 | exostosin glycosyltransferase 1 | -0.152548 |
| CD44 | CD44 molecule (Indian blood group) | -0.129126 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.121844 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.103411 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0977205 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0963199 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0943363 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0830236 |
| ANXA2 | annexin A2 | -0.0823914 |
| FTL | ferritin, light polypeptide | -0.069991 |
| AHNAK | AHNAK nucleoprotein | -0.0654674 |
| TXNRD1 | thioredoxin reductase 1 | -0.0623584 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0619052 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0593428 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0576892 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0552318 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0551652 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0549986 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0548994 |
| CANX | calnexin | -0.0543604 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0541134 |
| ACTG1 | actin gamma 1 | -0.0515552 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0510734 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0509559 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.049223 |
| DEK | DEK proto-oncogene | -0.0490318 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0482383 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0474193 |
| PGK1 | phosphoglycerate kinase 1 | -0.0473761 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0464087 |
| OSMR | oncostatin M receptor | -0.0463855 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0460536 |
| GLIS3 | GLIS family zinc finger 3 | -0.0449947 |
| IL6ST | interleukin 6 signal transducer | -0.0449845 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0441642 |
| ERBIN | erbb2 interacting protein | -0.0425286 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0420024 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0412999 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0399531 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0396738 |
| ATP13A3 | ATPase type 13A3 | -0.0389937 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0381506 |
| LDHA | lactate dehydrogenase A | -0.037964 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.037482 |
| GNAS | GNAS complex locus | -0.0369776 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.036772 |
| HLA-A | major histocompatibility complex, class I, A | -0.0366225 |
| MAP1B | microtubule-associated protein 1B | -0.0356095 |
| ZNF432 | zinc finger protein 432 | -0.0352996 |
| DIAPH3 | diaphanous-related formin 3 | -0.0349544 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0349149 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0346177 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0343796 |
| ARF1 | ADP-ribosylation factor 1 | -0.0342803 |
| MT2A | metallothionein 2A | -0.0338694 |
| CCND1 | cyclin D1 | -0.033719 |
| RAI14 | retinoic acid induced 14 | -0.0336602 |
| ASPH | aspartate beta-hydroxylase | -0.0335185 |
| MORF4L2 | mortality factor 4 like 2 | -0.0331707 |
| ENO1 | enolase 1, (alpha) | -0.0330277 |
| RTN4 | reticulon 4 | -0.0328642 |
| PLSCR1 | phospholipid scramblase 1 | -0.0327174 |
| FLNB | filamin B, beta | -0.0326877 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0323803 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0313746 |
| TUBB | tubulin, beta class I | -0.0309445 |
| NEK7 | NIMA-related kinase 7 | -0.0307307 |
| CDK17 | cyclin-dependent kinase 17 | -0.0306535 |
| PLCB4 | phospholipase C, beta 4 | -0.0306277 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0305836 |
| TMEM263 | transmembrane protein 263 | -0.0304737 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0304515 |
| NF1 | neurofibromin 1 | -0.0302924 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0302807 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0302039 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0299001 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.029834 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0296099 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0295958 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0291361 |
| JMJD1C | jumonji domain containing 1C | -0.0290302 |
| MT1X | metallothionein 1X | -0.0288498 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0283178 |
| ACTN4 | actinin, alpha 4 | -0.0282451 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0282173 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0280642 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0280322 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0277454 |
| SMAD3 | SMAD family member 3 | -0.0277116 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0276653 |
| SQSTM1 | sequestosome 1 | -0.0273387 |
| S100A10 | S100 calcium binding protein A10 | -0.0272901 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0272267 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0271835 |
| ZFR | zinc finger RNA binding protein | -0.0270358 |
| CAVIN1 | caveolae associated protein 1 | -0.026961 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | -0.0268463 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0265689 |
