| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DTNA | dystrobrevin, alpha | 0.249092 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.146102 |
| RACK1 | receptor for activated C kinase 1 | 0.128694 |
| CALD1 | caldesmon 1 | 0.114017 |
| EXT1 | exostosin glycosyltransferase 1 | 0.111392 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0908058 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0907428 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0773192 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0714815 |
| NUP58 | nucleoporin 58 | 0.0704981 |
| FLNA | filamin A, alpha | 0.0647572 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0586258 |
| RPS12 | ribosomal protein S12 | 0.0572608 |
| HDAC9 | histone deacetylase 9 | 0.0572086 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0548663 |
| SPAG9 | sperm associated antigen 9 | 0.0546185 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.054035 |
| TLE4 | transducin-like enhancer of split 4 | 0.0535255 |
| PRKCE | protein kinase C, epsilon | 0.0527474 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0525995 |
| RUNX1 | runt-related transcription factor 1 | 0.0503018 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0490431 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0478764 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0470781 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0469924 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0461129 |
| DST | dystonin | 0.0452803 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0442411 |
| NAV3 | neuron navigator 3 | 0.0432655 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0432523 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0426364 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0417154 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0415576 |
| RPL23 | ribosomal protein L23 | 0.040438 |
| RPL3 | ribosomal protein L3 | 0.0400252 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0396646 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.038599 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0384147 |
| TPM3 | tropomyosin 3 | 0.0383976 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0381378 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0378813 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0375862 |
| CFAP251 | cilia and flagella associated protein 251 | 0.0370631 |
| RPL7 | ribosomal protein L7 | 0.0364827 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0363375 |
| GOLGA4 | golgin A4 | 0.0363273 |
| PRRC2C | proline-rich coiled-coil 2C | 0.036184 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0357874 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0357398 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0356306 |
| SET | SET nuclear proto-oncogene | 0.034518 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0343782 |
| RPL37A | ribosomal protein L37a | 0.0343433 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0338737 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0336523 |
| RPL26 | ribosomal protein L26 | 0.0332501 |
| KIF5B | kinesin family member 5B | 0.0330287 |
| WDR45B | WD repeat domain 45B | 0.0327843 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0326695 |
| SMAP1 | small ArfGAP 1 | 0.0325426 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0325416 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0321028 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0320969 |
| RPL30 | ribosomal protein L30 | 0.031788 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0314951 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0314831 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0311676 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0305136 |
| ENKUR | enkurin, TRPC channel interacting protein | 0.0303082 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0302259 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0301168 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0300379 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0298095 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0296133 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0294023 |
| JMJD1C | jumonji domain containing 1C | 0.0293647 |
| NBAS | neuroblastoma amplified sequence | 0.0292104 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0291681 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0289665 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0283318 |
| RBM39 | RNA binding motif protein 39 | 0.0281083 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.028061 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0278483 |
| COG5 | component of oligomeric golgi complex 5 | 0.0276986 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0276494 |
| PLEC | plectin | 0.0275619 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0268575 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0268159 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0267629 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0264145 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0263357 |
| CORO1C | coronin, actin binding protein, 1C | 0.026265 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0260553 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0259461 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0257717 |
| CASC3 | cancer susceptibility candidate 3 | 0.0257141 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0255888 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0255415 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0255313 |
| WDR43 | WD repeat domain 43 | 0.025433 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.385391 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.109481 |
| PTMA | prothymosin, alpha | -0.0973451 |
| VIM | vimentin | -0.0936079 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0932751 |
| AHNAK | AHNAK nucleoprotein | -0.0872578 |
| FTL | ferritin, light polypeptide | -0.0813013 |
| TMSB10 | thymosin beta 10 | -0.0645183 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0644032 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0631742 |
| MMP12 | matrix metallopeptidase 12 | -0.0624531 |
| GPC6 | glypican 6 | -0.0545246 |
| EGR1 | early growth response 1 | -0.0540797 |
| VCL | vinculin | -0.0525827 |
| RIGI | RNA sensor RIG-I | -0.0495354 |
| CD44 | CD44 molecule (Indian blood group) | -0.0491126 |
| TXNIP | thioredoxin interacting protein | -0.0488496 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0483814 |
| RTN4 | reticulon 4 | -0.0470356 |
| NTM | neurotrimin | -0.0419264 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0396461 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0379287 |
| H1-0 | H1.0 linker histone | -0.0377917 |
| KIAA1549L | KIAA1549-like | -0.0355646 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0353786 |
| LSAMP | limbic system-associated membrane protein | -0.0344624 |
| IER3 | immediate early response 3 | -0.0344201 |
| SMAD3 | SMAD family member 3 | -0.0340633 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.03357 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0324531 |
| TNNC1 | troponin C type 1 (slow) | -0.0312389 |
| RPS6 | ribosomal protein S6 | -0.0294445 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0290931 |
| FOXP1 | forkhead box P1 | -0.0288726 |
| PTCHD4 | patched domain containing 4 | -0.0286022 |
| RPS24 | ribosomal protein S24 | -0.028245 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0280879 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0274174 |
| CTSB | cathepsin B | -0.0271937 |
| NABP1 | nucleic acid binding protein 1 | -0.0270693 |
| CDH13 | cadherin 13 | -0.0270346 |
| TENM2 | teneurin transmembrane protein 2 | -0.0261965 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0261305 |
| NAV1 | neuron navigator 1 | -0.0255993 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0252742 |
| MAP1B | microtubule-associated protein 1B | -0.0247345 |
| GNAS | GNAS complex locus | -0.0246632 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0244123 |
| HMGA1 | high mobility group AT-hook 1 | -0.0237002 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0236626 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.023559 |
| ATXN1 | ataxin 1 | -0.0234643 |
| MYOF | myoferlin | -0.0233842 |
| BNC2 | basonuclin 2 | -0.0233435 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0232127 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0231901 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.022935 |
| CUX1 | cut-like homeobox 1 | -0.0228455 |
| NDRG1 | N-myc downstream regulated 1 | -0.0227241 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0223948 |
| NLGN1 | neuroligin 1 | -0.0222479 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0221786 |
| RNF213 | ring finger protein 213 | -0.0219199 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0218632 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0215586 |
| MT2A | metallothionein 2A | -0.0213762 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0212642 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0212595 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0205827 |
| YBX3 | Y box binding protein 3 | -0.0204766 |
| PTK2 | protein tyrosine kinase 2 | -0.0203669 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0200036 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0196661 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0195835 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.019432 |
| RPLP0 | ribosomal protein, large, P0 | -0.0190216 |
| TPM4 | tropomyosin 4 | -0.0190209 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0189208 |
| WASF2 | WAS protein family, member 2 | -0.0186687 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0186373 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0184009 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0182408 |
| RPL6 | ribosomal protein L6 | -0.0180562 |
| RAD51B | RAD51 paralog B | -0.0180476 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0180007 |
| ASPH | aspartate beta-hydroxylase | -0.0178821 |
| RPS15 | ribosomal protein S15 | -0.0178401 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0178391 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0178215 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0177652 |
| EMP1 | epithelial membrane protein 1 | -0.0175396 |
| NHSL1 | NHS-like 1 | -0.0175254 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.017402 |
| ARF4 | ADP-ribosylation factor 4 | -0.0173159 |
| POTEF | POTE ankyrin domain family, member F | -0.0172781 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0172018 |
| NRP1 | neuropilin 1 | -0.017071 |
| JAZF1 | JAZF zinc finger 1 | -0.016996 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0169866 |
| RYBP | RING1 and YY1 binding protein | -0.0169215 |
