| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Levobupivacaine (hydrochloride)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.110316 |
| GOLGA4 | golgin A4 | 0.104378 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0976569 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0837497 |
| NDRG1 | N-myc downstream regulated 1 | 0.0796403 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0775619 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0660844 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0651573 |
| FAM13A | family with sequence similarity 13, member A | 0.0645249 |
| DSPP | dentin sialophosphoprotein | 0.0643549 |
| VEGFA | vascular endothelial growth factor A | 0.0632306 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0625873 |
| RACK1 | receptor for activated C kinase 1 | 0.0609522 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0594466 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.05943 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0592058 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0582392 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.05719 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0525448 |
| KIF5B | kinesin family member 5B | 0.0505186 |
| CALR | calreticulin | 0.0502249 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0487791 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0483619 |
| PTEN | phosphatase and tensin homolog | 0.0482425 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0459185 |
| HDLBP | high density lipoprotein binding protein | 0.0454721 |
| RPL3 | ribosomal protein L3 | 0.0453636 |
| RBM39 | RNA binding motif protein 39 | 0.044408 |
| CANX | calnexin | 0.0442599 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0440006 |
| PRELID2 | PRELI domain containing 2 | 0.0438567 |
| RNF43 | ring finger protein 43 | 0.0431654 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0417031 |
| OGA | O-GlcNAcase | 0.040613 |
| YBX1 | Y box binding protein 1 | 0.0385299 |
| EREG | epiregulin | 0.038293 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0379093 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0351462 |
| TPM3 | tropomyosin 3 | 0.03477 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0342557 |
| RNF145 | ring finger protein 145 | 0.0339739 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.033738 |
| ZNF292 | zinc finger protein 292 | 0.0336095 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0334994 |
| DNM2 | dynamin 2 | 0.0333513 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0329957 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0324666 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0324068 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0323259 |
| NEBL | nebulette | 0.0322836 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0322628 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0320999 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0320328 |
| NCOR1 | nuclear receptor corepressor 1 | 0.03174 |
| TMF1 | TATA element modulatory factor 1 | 0.0316506 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0314473 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0307594 |
| NUP58 | nucleoporin 58 | 0.030616 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0304274 |
| SCFD1 | sec1 family domain containing 1 | 0.0301528 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0300179 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0299357 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0298263 |
| NBAS | neuroblastoma amplified sequence | 0.0298014 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0295693 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0295469 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0291768 |
| ATXN1 | ataxin 1 | 0.0291165 |
| HELZ | helicase with zinc finger | 0.0287512 |
| SRP54 | signal recognition particle 54kDa | 0.0287308 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0282964 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0281473 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0280665 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0279616 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0279277 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0277749 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0271319 |
| WDR45B | WD repeat domain 45B | 0.0270166 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.026952 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0269082 |
| TXNIP | thioredoxin interacting protein | 0.0265827 |
| YTHDC1 | YTH domain containing 1 | 0.0265396 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.0264388 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0263797 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0263691 |
| YME1L1 | YME1-like 1 ATPase | 0.0260082 |
| CCNY | cyclin Y | 0.0258728 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0258647 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.025761 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0257177 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0256711 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0254541 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0254195 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.025384 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0253396 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0252421 |
| METTL15 | methyltransferase like 15 | 0.0252151 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0252001 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0250014 |
| SNX13 | sorting nexin 13 | 0.0248346 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.241032 |
| NPSR1 | neuropeptide S receptor 1 | -0.152572 |
| TMSB10 | thymosin beta 10 | -0.140209 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.126399 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0958552 |
| MYO1E | myosin IE | -0.095535 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0937613 |
| VCL | vinculin | -0.0888288 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0775304 |
| PTMA | prothymosin, alpha | -0.072586 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0691006 |
| RPS6 | ribosomal protein S6 | -0.0634855 |
| ACTG1 | actin gamma 1 | -0.0567933 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0562827 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.05413 |
| ANTXR2 | anthrax toxin receptor 2 | -0.051739 |
| MT2A | metallothionein 2A | -0.0507829 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0496413 |
| RPL35A | ribosomal protein L35a | -0.0464538 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0459565 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0456423 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0448407 |
| S100A6 | S100 calcium binding protein A6 | -0.0441349 |
| AHNAK | AHNAK nucleoprotein | -0.0440247 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0437857 |
| RPS24 | ribosomal protein S24 | -0.0418214 |
| RPLP2 | ribosomal protein, large, P2 | -0.0416 |
| FTL | ferritin, light polypeptide | -0.0395966 |
| LAMA4 | laminin, alpha 4 | -0.0395156 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0382343 |
| IER3 | immediate early response 3 | -0.0380287 |
| ANXA2 | annexin A2 | -0.0369498 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0369451 |
| RPL34 | ribosomal protein L34 | -0.0356772 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0347515 |
| S100A10 | S100 calcium binding protein A10 | -0.0338758 |
| EGR1 | early growth response 1 | -0.0338214 |
| FHIT | fragile histidine triad | -0.0330358 |
| CADPS | Ca++-dependent secretion activator | -0.0322932 |
| RPS25 | ribosomal protein S25 | -0.0322652 |
| RPS23 | ribosomal protein S23 | -0.0319147 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0314671 |
| CCND1 | cyclin D1 | -0.0308853 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0303103 |
| RPS11 | ribosomal protein S11 | -0.0293781 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0288941 |
| TPM1 | tropomyosin 1 (alpha) | -0.0288928 |
| TPM4 | tropomyosin 4 | -0.0288749 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0287532 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0285977 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0282611 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.02823 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0280129 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0275435 |
| RPL7A | ribosomal protein L7a | -0.0270814 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0269054 |
| SMYD3 | SET and MYND domain containing 3 | -0.026875 |
| PALLD | palladin, cytoskeletal associated protein | -0.0267529 |
| TFF1 | trefoil factor 1 | -0.0266376 |
| RPL9 | ribosomal protein L9 | -0.0265694 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0265251 |
| RPS29 | ribosomal protein S29 | -0.0263587 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0262877 |
| RPS19 | ribosomal protein S19 | -0.0261518 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0260587 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.025839 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0254744 |
| RPS27A | ribosomal protein S27a | -0.0252069 |
| RPL32 | ribosomal protein L32 | -0.0251332 |
| LDHA | lactate dehydrogenase A | -0.0248321 |
| RPL31 | ribosomal protein L31 | -0.0248266 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0248028 |
| RPLP1 | ribosomal protein, large, P1 | -0.0247771 |
| ONECUT3 | one cut homeobox 3 | -0.0246801 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0245165 |
| RPL36 | ribosomal protein L36 | -0.0244761 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0243388 |
| RPL28 | ribosomal protein L28 | -0.0240773 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0238734 |
| RPL19 | ribosomal protein L19 | -0.0236729 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0234434 |
| PCDH9 | protocadherin 9 | -0.02312 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0228996 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0228231 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0226904 |
| S100A9 | S100 calcium binding protein A9 | -0.0226784 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0225338 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0223019 |
| RPS5 | ribosomal protein S5 | -0.0221276 |
| PKM | pyruvate kinase, muscle | -0.0220404 |
| RPS16 | ribosomal protein S16 | -0.0220011 |
| RPS15 | ribosomal protein S15 | -0.021605 |
| DIAPH2 | diaphanous-related formin 2 | -0.0214804 |
| KRT19 | keratin 19, type I | -0.021476 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0212335 |
| MT1X | metallothionein 1X | -0.0210991 |
| SVIL | supervillin | -0.0210711 |
| RPS10 | ribosomal protein S10 | -0.0209637 |
| RPL37 | ribosomal protein L37 | -0.020773 |
| RPL38 | ribosomal protein L38 | -0.0206654 |
