| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RACK1 | receptor for activated C kinase 1 | 0.158229 |
| TMSB4X | thymosin beta 4, X-linked | 0.120219 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.117016 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.114092 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.11376 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0903778 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0865411 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.074848 |
| CENPF | centromere protein F, 350/400kDa | 0.0686897 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0683997 |
| RPL35A | ribosomal protein L35a | 0.0657161 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.055822 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0534582 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0525567 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0523649 |
| YBX1 | Y box binding protein 1 | 0.0498408 |
| SLK | STE20-like kinase | 0.0495375 |
| KPNB1 | karyopherin (importin) beta 1 | 0.049408 |
| WDR43 | WD repeat domain 43 | 0.0478131 |
| PGK1 | phosphoglycerate kinase 1 | 0.0478033 |
| RAI1 | retinoic acid induced 1 | 0.0470882 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0465918 |
| RPL3 | ribosomal protein L3 | 0.046202 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0450897 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.044402 |
| TMEM123 | transmembrane protein 123 | 0.0439745 |
| HLA-B | major histocompatibility complex, class I, B | 0.0435455 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0431603 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0430034 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0429052 |
| RPS6 | ribosomal protein S6 | 0.0420413 |
| RPL23 | ribosomal protein L23 | 0.0415559 |
| RPL12 | ribosomal protein L12 | 0.0406398 |
| RPS2 | ribosomal protein S2 | 0.0387872 |
| TPM4 | tropomyosin 4 | 0.0378786 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0376951 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0375804 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0373126 |
| CBX3 | chromobox homolog 3 | 0.0372564 |
| ADAR | adenosine deaminase, RNA-specific | 0.0371342 |
| CCNL1 | cyclin L1 | 0.0363625 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0363294 |
| RPLP0 | ribosomal protein, large, P0 | 0.0361814 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0360758 |
| TPI1 | triosephosphate isomerase 1 | 0.0356484 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0355592 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0354692 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0350943 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.034862 |
| B2M | beta-2-microglobulin | 0.0344656 |
| RPL37 | ribosomal protein L37 | 0.0341163 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0336243 |
| CD44 | CD44 molecule (Indian blood group) | 0.0335857 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0333577 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0333526 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0333046 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0332966 |
| EGR1 | early growth response 1 | 0.033258 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0328835 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0328704 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0328602 |
| RPL11 | ribosomal protein L11 | 0.0324361 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0321491 |
| MAP4 | microtubule-associated protein 4 | 0.0319935 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0313756 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0310501 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.030953 |
| PLK2 | polo-like kinase 2 | 0.0309412 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0306717 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0305285 |
| PODXL | podocalyxin-like | 0.0304543 |
| SZRD1 | SUZ RNA binding domain containing 1 | 0.0300215 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0298944 |
| FTL | ferritin, light polypeptide | 0.0297036 |
| NUP58 | nucleoporin 58 | 0.0295442 |
| EZR | ezrin | 0.0295041 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.029287 |
| MKI67 | marker of proliferation Ki-67 | 0.0290785 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0290435 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0287538 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0287385 |
| RPS12 | ribosomal protein S12 | 0.0286011 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0284011 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0281821 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0280664 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0280521 |
| RUNX1 | runt-related transcription factor 1 | 0.0279013 |
| HMGA1 | high mobility group AT-hook 1 | 0.0277956 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0274769 |
| ARF6 | ADP-ribosylation factor 6 | 0.0269682 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.026812 |
| LRRC49 | leucine rich repeat containing 49 | 0.0268088 |
| KRT18 | keratin 18, type I | 0.0267711 |
| FOSL1 | FOS-like antigen 1 | 0.0267493 |
| SET | SET nuclear proto-oncogene | 0.026585 |
| VCL | vinculin | 0.0265423 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 0.0265072 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0264988 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0264392 |
| YME1L1 | YME1-like 1 ATPase | 0.0263964 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.188724 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.171892 |
| UBC | ubiquitin C | -0.158011 |
| MT2A | metallothionein 2A | -0.155491 |
| TMSB10 | thymosin beta 10 | -0.130728 |
| VIM | vimentin | -0.125388 |
| RPS27A | ribosomal protein S27a | -0.100985 |
| JUN | jun proto-oncogene | -0.0910525 |
| AHNAK | AHNAK nucleoprotein | -0.075109 |
| MT1X | metallothionein 1X | -0.0695426 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0578162 |
| EMP1 | epithelial membrane protein 1 | -0.054177 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0522678 |
| USP34 | ubiquitin specific peptidase 34 | -0.0519752 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0516338 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0509388 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0502007 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0499847 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0476045 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0451778 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0442375 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0435538 |
| PTMA | prothymosin, alpha | -0.0435319 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0404005 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0402612 |
| FNIP1 | folliculin interacting protein 1 | -0.0398491 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0396166 |
| HDAC9 | histone deacetylase 9 | -0.0370891 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0367187 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.036093 |
| ZNF638 | zinc finger protein 638 | -0.0331555 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0329344 |
| S100A6 | S100 calcium binding protein A6 | -0.032058 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0320398 |
| PRELID2 | PRELI domain containing 2 | -0.0319377 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0312649 |
| CMIP | c-Maf inducing protein | -0.0311995 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0310173 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0309553 |
| INTS6 | integrator complex subunit 6 | -0.0306644 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0304274 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0303777 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0301566 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0297837 |
| SDC4 | syndecan 4 | -0.0295303 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0289361 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0287562 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0286241 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.028473 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0284415 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.028064 |
| USP12 | ubiquitin specific peptidase 12 | -0.0275492 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0274868 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0272485 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0268433 |
| OGA | O-GlcNAcase | -0.0265214 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | -0.0263775 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0262978 |
| NPAS2 | neuronal PAS domain protein 2 | -0.026184 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0261662 |
| MCL1 | myeloid cell leukemia 1 | -0.0254461 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0253804 |
| VMP1 | vacuole membrane protein 1 | -0.025361 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0252062 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0246096 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.024477 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0241147 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0240209 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0238856 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0237938 |
| COPA | coatomer protein complex, subunit alpha | -0.0237235 |
| EXOC4 | exocyst complex component 4 | -0.0236929 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0236858 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.023516 |
| CADM2 | cell adhesion molecule 2 | -0.0230389 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0230129 |
| TUT7 | terminal uridylyl transferase 7 | -0.0229887 |
| PUS7 | pseudouridylate synthase 7 (putative) | -0.0229321 |
| PCBP2 | poly(rC) binding protein 2 | -0.0228554 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0228319 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0228094 |
| SVIL | supervillin | -0.0226071 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0223379 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0222933 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0222452 |
| MLPH | melanophilin | -0.0222171 |
| DST | dystonin | -0.0221427 |
| CFDP1 | craniofacial development protein 1 | -0.0220977 |
| RTN4 | reticulon 4 | -0.0218703 |
| S100A10 | S100 calcium binding protein A10 | -0.0218143 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.021726 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0216516 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0212745 |
| UPP1 | uridine phosphorylase 1 | -0.0212488 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0210744 |
| SETX | senataxin | -0.0209686 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0206132 |
| ZNF609 | zinc finger protein 609 | -0.0204886 |
| MYO9A | myosin IXA | -0.0203572 |
| SKI | SKI proto-oncogene | -0.0201527 |
