| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.125876 |
| TXNRD1 | thioredoxin reductase 1 | 0.112629 |
| TBC1D22A | TBC1 domain family, member 22A | 0.092026 |
| NDRG1 | N-myc downstream regulated 1 | 0.0672266 |
| MKI67 | marker of proliferation Ki-67 | 0.0657416 |
| NGLY1 | N-glycanase 1 | 0.059953 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0530573 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0480059 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0471064 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0461403 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0424531 |
| PLEC | plectin | 0.041359 |
| FAM13A | family with sequence similarity 13, member A | 0.0380548 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0370555 |
| CES1 | carboxylesterase 1 | 0.0353418 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0349655 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0343775 |
| ARRDC3 | arrestin domain containing 3 | 0.033909 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0320183 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0314312 |
| HDLBP | high density lipoprotein binding protein | 0.0313517 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0304134 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0281494 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0280382 |
| TPD52 | tumor protein D52 | 0.0279813 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0267805 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0266704 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0263349 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0255219 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0253522 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0252782 |
| NDE1 | nudE neurodevelopment protein 1 | 0.0246731 |
| GPATCH2L | G patch domain containing 2-like | 0.0244483 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0242063 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0234858 |
| EGFR | epidermal growth factor receptor | 0.0228738 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0227848 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0219151 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0216737 |
| TMEM165 | transmembrane protein 165 | 0.0215033 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0211259 |
| CUL4A | cullin 4A | 0.0204996 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0204557 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0201902 |
| KLC1 | kinesin light chain 1 | 0.0201552 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0197464 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0195978 |
| HYOU1 | hypoxia up-regulated 1 | 0.0194847 |
| SMAD3 | SMAD family member 3 | 0.0194677 |
| KIAA1217 | KIAA1217 | 0.0194424 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0194084 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0192426 |
| USP34 | ubiquitin specific peptidase 34 | 0.0192332 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0191406 |
| MYO1B | myosin IB | 0.0189584 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.0189577 |
| OGA | O-GlcNAcase | 0.0189092 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0187823 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0187666 |
| WDR45B | WD repeat domain 45B | 0.0187385 |
| EP300 | E1A binding protein p300 | 0.0186599 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0186293 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.018578 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.018561 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0183105 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0181555 |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | 0.0180802 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.017742 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0177387 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0177258 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0176449 |
| LAMB3 | laminin, beta 3 | 0.0176091 |
| SQSTM1 | sequestosome 1 | 0.0176069 |
| CANX | calnexin | 0.0175834 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0174775 |
| RBM39 | RNA binding motif protein 39 | 0.0174547 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0173145 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0172937 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0171768 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0170786 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0170653 |
| TXNDC11 | thioredoxin domain containing 11 | 0.0170523 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0169648 |
| ABLIM1 | actin binding LIM protein 1 | 0.016822 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0165338 |
| METTL15 | methyltransferase like 15 | 0.0163817 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0163475 |
| RNF169 | ring finger protein 169 | 0.0163072 |
| CTTN | cortactin | 0.0161587 |
| VEGFA | vascular endothelial growth factor A | 0.0160414 |
| HELZ | helicase with zinc finger | 0.0160137 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0159528 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0159334 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0159318 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.015917 |
| ZNF638 | zinc finger protein 638 | 0.0157445 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0156242 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0155588 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0154556 |
| CENPF | centromere protein F, 350/400kDa | 0.0154003 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.143658 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.140231 |
| TMSB10 | thymosin beta 10 | -0.0941572 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0782304 |
| LMO7 | LIM domain 7 | -0.0680078 |
| ACTG1 | actin gamma 1 | -0.0613992 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0613749 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0598007 |
| MT2A | metallothionein 2A | -0.0546771 |
| EGR1 | early growth response 1 | -0.0532754 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0514044 |
| S100A10 | S100 calcium binding protein A10 | -0.0506793 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0494065 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0489045 |
| INTS6 | integrator complex subunit 6 | -0.0487619 |
| MYOF | myoferlin | -0.0443055 |
| NABP1 | nucleic acid binding protein 1 | -0.0438172 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0436478 |
| ASPH | aspartate beta-hydroxylase | -0.0415534 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0406178 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0400362 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.039389 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0389438 |
| ANXA2 | annexin A2 | -0.0380779 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0380705 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0377709 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0363484 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0361044 |
| CUX1 | cut-like homeobox 1 | -0.0360355 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0359926 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0356559 |
| PKM | pyruvate kinase, muscle | -0.0353452 |
| CST3 | cystatin C | -0.0336233 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.033081 |
| SCEL | sciellin | -0.0326013 |
| APP | amyloid beta (A4) precursor protein | -0.0323543 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0322404 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0312581 |
| LAMA4 | laminin, alpha 4 | -0.0312558 |
| GRAMD1B | GRAM domain containing 1B | -0.0301018 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0295262 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.028974 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0286465 |
| TJP1 | tight junction protein 1 | -0.0286124 |
| GPC6 | glypican 6 | -0.0282088 |
| MYO1E | myosin IE | -0.0280972 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0280892 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0277769 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0277036 |
| AREG | amphiregulin | -0.0271071 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0269388 |
| KRT7 | keratin 7, type II | -0.0265862 |
| TOP1 | topoisomerase (DNA) I | -0.0263458 |
| FTL | ferritin, light polypeptide | -0.0263304 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0260454 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0258398 |
| SLC38A2 | solute carrier family 38, member 2 | -0.025545 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.025466 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0252485 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0250698 |
| LDHA | lactate dehydrogenase A | -0.0247076 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0247055 |
| TPM4 | tropomyosin 4 | -0.0243536 |
| BBX | bobby sox homolog (Drosophila) | -0.0241706 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0240514 |
| EFNA5 | ephrin-A5 | -0.0239937 |
| SMYD3 | SET and MYND domain containing 3 | -0.0237613 |
| FOXP1 | forkhead box P1 | -0.0236442 |
| LAMC2 | laminin, gamma 2 | -0.0234863 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0232027 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0231221 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0225355 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0223996 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0223396 |
| OSMR | oncostatin M receptor | -0.0212613 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0210601 |
| VCL | vinculin | -0.0208354 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.020737 |
| USP53 | ubiquitin specific peptidase 53 | -0.0205604 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.02046 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0202545 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0199621 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0199558 |
| GPHN | gephyrin | -0.0198964 |
| NTN4 | netrin 4 | -0.0197575 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0195751 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.019461 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0194067 |
| MAP7 | microtubule-associated protein 7 | -0.0192962 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0192591 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.0189789 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0188614 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0188019 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0186998 |
| MORF4L2 | mortality factor 4 like 2 | -0.0186921 |
| ENO1 | enolase 1, (alpha) | -0.0186207 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0185761 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0184561 |
| ANXA1 | annexin A1 | -0.0184252 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0182126 |
