| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Levobupivacaine (hydrochloride)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAV2 | neuron navigator 2 | 0.090551 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.088422 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0856546 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0764295 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0752046 |
| VEGFA | vascular endothelial growth factor A | 0.0721493 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0715387 |
| PCBP2 | poly(rC) binding protein 2 | 0.0712002 |
| STC1 | stanniocalcin 1 | 0.0591489 |
| YBX1 | Y box binding protein 1 | 0.0562712 |
| CDH13 | cadherin 13 | 0.0544211 |
| SMAD3 | SMAD family member 3 | 0.0533858 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0484248 |
| SEPTIN9 | septin 9 | 0.0473402 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0467798 |
| RACK1 | receptor for activated C kinase 1 | 0.0465984 |
| GOLGA4 | golgin A4 | 0.0463847 |
| CALR | calreticulin | 0.0450871 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0441119 |
| EGFR | epidermal growth factor receptor | 0.0440142 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0426365 |
| OPTN | optineurin | 0.0423102 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0417174 |
| SBF2 | SET binding factor 2 | 0.0406111 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0397854 |
| AAK1 | AP2 associated kinase 1 | 0.0397498 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0397281 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0396389 |
| PGM3 | phosphoglucomutase 3 | 0.0391973 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0382007 |
| RPS12 | ribosomal protein S12 | 0.0380719 |
| GOLGB1 | golgin B1 | 0.0361761 |
| ATF7 | activating transcription factor 7 | 0.0354257 |
| RPL3 | ribosomal protein L3 | 0.0353746 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0350773 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0344965 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0343231 |
| HYOU1 | hypoxia up-regulated 1 | 0.0342689 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0341209 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0330829 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0330559 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0328194 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0321052 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0321042 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0313039 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0312759 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0309582 |
| ITSN2 | intersectin 2 | 0.030932 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0307749 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0306666 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.030182 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0301026 |
| MTSS1 | metastasis suppressor 1 | 0.0297073 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0296689 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0296625 |
| MEF2A | myocyte enhancer factor 2A | 0.0296608 |
| FAM107B | family with sequence similarity 107, member B | 0.0296291 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.029524 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0292516 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0291294 |
| GOSR2 | golgi SNAP receptor complex member 2 | 0.0290038 |
| PYGL | phosphorylase, glycogen, liver | 0.028974 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.028476 |
| HDLBP | high density lipoprotein binding protein | 0.0278252 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0278038 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0277142 |
| CLTC | clathrin, heavy chain (Hc) | 0.0275635 |
| SCFD1 | sec1 family domain containing 1 | 0.0275076 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0275035 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0274574 |
| SLFN5 | schlafen family member 5 | 0.0273183 |
| PAPOLA | poly(A) polymerase alpha | 0.0273073 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0273066 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0268904 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0268568 |
| MKRN1 | makorin ring finger protein 1 | 0.0267444 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.0266433 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0265067 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0263172 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0261207 |
| COPA | coatomer protein complex, subunit alpha | 0.0260518 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.026019 |
| GPATCH2L | G patch domain containing 2-like | 0.0258589 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0258425 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa | 0.0254897 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0253747 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0253324 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0252816 |
| FLNA | filamin A, alpha | 0.0250934 |
| PTEN | phosphatase and tensin homolog | 0.025016 |
| HEATR5A | HEAT repeat containing 5A | 0.0248847 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0248232 |
| SMAD4 | SMAD family member 4 | 0.0248147 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0247601 |
| SEPTIN2 | septin 2 | 0.0247514 |
| GOLGA3 | golgin A3 | 0.0247129 |
| POTEF | POTE ankyrin domain family, member F | 0.0246484 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0244914 |
| B2M | beta-2-microglobulin | 0.0244762 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0241356 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.205544 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.175474 |
| CD44 | CD44 molecule (Indian blood group) | -0.125836 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.117536 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.104221 |
| TMSB10 | thymosin beta 10 | -0.0837317 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0794555 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0736298 |
| IER3 | immediate early response 3 | -0.0713563 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0654254 |
| FNDC3B | fibronectin type III domain containing 3B | -0.062683 |
| ETV6 | ets variant 6 | -0.0612685 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0581782 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0573613 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0560802 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0559235 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0552065 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0540623 |
| GPC6 | glypican 6 | -0.0533139 |
| FTL | ferritin, light polypeptide | -0.0531995 |
| ASPH | aspartate beta-hydroxylase | -0.0517135 |
| DST | dystonin | -0.0504318 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0487093 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0485591 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0480341 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.045895 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0456368 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0455754 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0435374 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0433516 |
| NRG1 | neuregulin 1 | -0.0432588 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0421519 |
| PTMA | prothymosin, alpha | -0.0414973 |
| H1-0 | H1.0 linker histone | -0.0411015 |
| HMGA2 | high mobility group AT-hook 2 | -0.0410683 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0400857 |
| OSMR | oncostatin M receptor | -0.0396766 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0394633 |
| EGR1 | early growth response 1 | -0.0382155 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.03806 |
| ZNF292 | zinc finger protein 292 | -0.0378372 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0368741 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0367566 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0367455 |
| RBM39 | RNA binding motif protein 39 | -0.0366989 |
| RUNX2 | runt-related transcription factor 2 | -0.0362121 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0360652 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0350898 |
| ANXA2 | annexin A2 | -0.0349478 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0347592 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0340782 |
| PARD3 | par-3 family cell polarity regulator | -0.0337775 |
| TMEM263 | transmembrane protein 263 | -0.0332459 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0327422 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0323277 |
| ATXN1 | ataxin 1 | -0.0323237 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0313472 |
| BMERB1 | bMERB domain containing 1 | -0.0313013 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.03052 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0303743 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.030274 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0301362 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0299864 |
| MT2A | metallothionein 2A | -0.0299218 |
| GLIS3 | GLIS family zinc finger 3 | -0.0297259 |
| ZNF385D | zinc finger protein 385D | -0.0294859 |
| RAD51B | RAD51 paralog B | -0.0293504 |
| WDR45B | WD repeat domain 45B | -0.029339 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0293197 |
| RNF24 | ring finger protein 24 | -0.0292598 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0291732 |
| MX2 | MX dynamin-like GTPase 2 | -0.0289252 |
| RAI14 | retinoic acid induced 14 | -0.0287355 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0284866 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0284377 |
| IL1R1 | interleukin 1 receptor, type I | -0.0280272 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0280098 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0273576 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0271014 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0270439 |
| EREG | epiregulin | -0.026979 |
| SQSTM1 | sequestosome 1 | -0.0269295 |
| GNAS | GNAS complex locus | -0.0268977 |
| LOX | lysyl oxidase | -0.026429 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0263402 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0261991 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0261908 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.025905 |
| AHNAK | AHNAK nucleoprotein | -0.0256023 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0255009 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0254636 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0252716 |
| SEPTIN7 | septin 7 | -0.0252454 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0251934 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0250444 |
| KLF6 | Kruppel-like factor 6 | -0.0249445 |
| PLSCR1 | phospholipid scramblase 1 | -0.0247005 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0246433 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.024578 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | -0.0244928 |
