| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.110515 |
| TPM3 | tropomyosin 3 | 0.0977155 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0781401 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0769555 |
| RACK1 | receptor for activated C kinase 1 | 0.0632103 |
| RPL23 | ribosomal protein L23 | 0.0630103 |
| RPL3 | ribosomal protein L3 | 0.061301 |
| FGB | fibrinogen beta chain | 0.0596347 |
| YBX1 | Y box binding protein 1 | 0.054298 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0525478 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0490153 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0428389 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0426171 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0425514 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0415761 |
| CCNL1 | cyclin L1 | 0.0402759 |
| B2M | beta-2-microglobulin | 0.0378637 |
| HYOU1 | hypoxia up-regulated 1 | 0.0377988 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0374713 |
| HDGF | hepatoma-derived growth factor | 0.0372756 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0362351 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0360822 |
| RPS12 | ribosomal protein S12 | 0.0359044 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0350904 |
| CALR | calreticulin | 0.0345826 |
| POTEF | POTE ankyrin domain family, member F | 0.0336484 |
| SERF2 | small EDRK-rich factor 2 | 0.0328919 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0313094 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0312847 |
| FLNA | filamin A, alpha | 0.0306748 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0295049 |
| ENO1 | enolase 1, (alpha) | 0.0289643 |
| ANXA5 | annexin A5 | 0.0281084 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.027294 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0269452 |
| MSN | moesin | 0.026133 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0261231 |
| PCBP2 | poly(rC) binding protein 2 | 0.0260582 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0259109 |
| RAI1 | retinoic acid induced 1 | 0.0255253 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0251491 |
| SET | SET nuclear proto-oncogene | 0.0251365 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0250459 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0242358 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.02382 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0237289 |
| MATR3 | matrin 3 | 0.0236261 |
| ANXA1 | annexin A1 | 0.0236123 |
| CASC3 | cancer susceptibility candidate 3 | 0.0227171 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0226592 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0223889 |
| NUP58 | nucleoporin 58 | 0.0223685 |
| MYO1B | myosin IB | 0.022215 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0220373 |
| CALU | calumenin | 0.0220335 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0219716 |
| PFDN2 | prefoldin subunit 2 | 0.0219031 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0217262 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0215304 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0213648 |
| RPS17 | ribosomal protein S17 | 0.0210851 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.021063 |
| PFN1 | profilin 1 | 0.0208818 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0208087 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.020671 |
| RPL37A | ribosomal protein L37a | 0.020553 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0205313 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0198725 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.019833 |
| PLEC | plectin | 0.0197203 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0194917 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0194125 |
| SSRP1 | structure specific recognition protein 1 | 0.0193827 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0193566 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0191087 |
| RPS3 | ribosomal protein S3 | 0.0190903 |
| ATP5F1A | ATP synthase F1 subunit alpha | 0.0189848 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.0189343 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.018873 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.018821 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0186506 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0186408 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0186269 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0184155 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0183976 |
| LDHB | lactate dehydrogenase B | 0.0181072 |
| RPS2 | ribosomal protein S2 | 0.0180041 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.017875 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0178289 |
| RPS27 | ribosomal protein S27 | 0.0176565 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0175393 |
| TCP1 | t-complex 1 | 0.0172393 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0169998 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0169936 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0168279 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0166688 |
| BMPR1B | bone morphogenetic protein receptor, type IB | 0.016523 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0164835 |
| STC2 | stanniocalcin 2 | 0.0164019 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0162998 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.229927 |
| GRAMD1B | GRAM domain containing 1B | -0.187807 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.170356 |
| PM20D1 | peptidase M20 domain containing 1 | -0.165991 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.132422 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.114308 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.113009 |
| ACTG1 | actin gamma 1 | -0.089807 |
| VIM | vimentin | -0.0830342 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0740724 |
| KYNU | kynureninase | -0.0699122 |
| OSMR | oncostatin M receptor | -0.0689719 |
| SVIL | supervillin | -0.0636531 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0634144 |
| HDAC9 | histone deacetylase 9 | -0.0608312 |
| ASPH | aspartate beta-hydroxylase | -0.0607879 |
| TMSB10 | thymosin beta 10 | -0.0600233 |
| MT2A | metallothionein 2A | -0.0588557 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0565567 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0565001 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0539908 |
| BICC1 | BicC family RNA binding protein 1 | -0.0529755 |
| IER3 | immediate early response 3 | -0.0521627 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0513696 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0512158 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0500736 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0496201 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0488067 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0447311 |
| USP34 | ubiquitin specific peptidase 34 | -0.0445856 |
| DENND4A | DENN/MADD domain containing 4A | -0.0443334 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0438289 |
| FAM107B | family with sequence similarity 107, member B | -0.0435978 |
| SMAD2 | SMAD family member 2 | -0.0435167 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0431335 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0419504 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0417317 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0413117 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0412433 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0401122 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0396935 |
| EGR1 | early growth response 1 | -0.0394865 |
| WWOX | WW domain containing oxidoreductase | -0.03946 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0392734 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0391731 |
| RASAL2 | RAS protein activator like 2 | -0.0380333 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0373178 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0360846 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0357802 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.035777 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0357348 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0351785 |
| GLIS3 | GLIS family zinc finger 3 | -0.0343729 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0331291 |
| NABP1 | nucleic acid binding protein 1 | -0.0329278 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0324576 |
| CMIP | c-Maf inducing protein | -0.0321732 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0316826 |
| DST | dystonin | -0.0315678 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0314178 |
| IGF2 | insulin-like growth factor 2 | -0.0307839 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0305294 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0304565 |
| AK1 | adenylate kinase 1 | -0.0303949 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0303652 |
| CDK13 | cyclin-dependent kinase 13 | -0.0302171 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0299335 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0299233 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0297972 |
| EFNA5 | ephrin-A5 | -0.0295946 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0291581 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0290628 |
| ZNF804A | zinc finger protein 804A | -0.0290346 |
| PHF3 | PHD finger protein 3 | -0.0287187 |
| MIPOL1 | mirror-image polydactyly 1 | -0.028631 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0284773 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0284408 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0282691 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0282289 |
| RBM39 | RNA binding motif protein 39 | -0.0282124 |
| RTN4 | reticulon 4 | -0.0279638 |
| NEGR1 | neuronal growth regulator 1 | -0.0279572 |
| SQSTM1 | sequestosome 1 | -0.0278134 |
| NF1 | neurofibromin 1 | -0.0277999 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0275784 |
| RHEB | Ras homolog enriched in brain | -0.0272047 |
| KLF6 | Kruppel-like factor 6 | -0.0268118 |
| JMJD1C | jumonji domain containing 1C | -0.0268062 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0264699 |
| RAB10 | RAB10, member RAS oncogene family | -0.0259115 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0257846 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0256379 |
| PCNX1 | pecanex 1 | -0.0255375 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0255327 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0255191 |
| FBXO11 | F-box protein 11 | -0.025484 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0251942 |
| PTK2 | protein tyrosine kinase 2 | -0.025168 |
| TCF12 | transcription factor 12 | -0.024743 |
| CDK12 | cyclin-dependent kinase 12 | -0.0246307 |
