| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.138179 |
| NDRG1 | N-myc downstream regulated 1 | 0.135233 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.100858 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0728746 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0723515 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0715391 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0703655 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0673824 |
| NRG1 | neuregulin 1 | 0.0673118 |
| TXNRD1 | thioredoxin reductase 1 | 0.0644241 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0640337 |
| PTMA | prothymosin, alpha | 0.0637934 |
| MED13L | mediator complex subunit 13-like | 0.0630514 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0628067 |
| PCBP2 | poly(rC) binding protein 2 | 0.0594065 |
| POTEF | POTE ankyrin domain family, member F | 0.0591318 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.056074 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0552842 |
| RPS3 | ribosomal protein S3 | 0.0547094 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0542384 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0534791 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0530585 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.052633 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0525928 |
| OGA | O-GlcNAcase | 0.0510462 |
| CANX | calnexin | 0.0501969 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.049964 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.049759 |
| FLNB | filamin B, beta | 0.0489089 |
| VIM | vimentin | 0.0488103 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0477002 |
| LDHA | lactate dehydrogenase A | 0.0476129 |
| CCDC88A | coiled-coil domain containing 88A | 0.0474573 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0473839 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0467041 |
| UBC | ubiquitin C | 0.0465928 |
| XPO1 | exportin 1 | 0.0457651 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.045407 |
| SETD5 | SET domain containing 5 | 0.0453431 |
| NPSR1 | neuropeptide S receptor 1 | 0.0449049 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0446031 |
| NRAS | neuroblastoma RAS viral (v-ras) oncogene homolog | 0.0428093 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.042513 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0422429 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0421929 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0419164 |
| NCKAP1 | NCK-associated protein 1 | 0.041067 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0407387 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0406494 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0406021 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0405218 |
| NLGN1 | neuroligin 1 | 0.0403594 |
| ATXN1 | ataxin 1 | 0.0398918 |
| RYBP | RING1 and YY1 binding protein | 0.0395454 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0395433 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0394501 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0389652 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0383919 |
| RLF | rearranged L-myc fusion | 0.0383141 |
| ARF4 | ADP-ribosylation factor 4 | 0.0377824 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0375291 |
| PGK1 | phosphoglycerate kinase 1 | 0.0372316 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0372051 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0369396 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.036744 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0367354 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0362686 |
| RTN4 | reticulon 4 | 0.0360377 |
| RPS4X | ribosomal protein S4, X-linked | 0.0359888 |
| FAM13A | family with sequence similarity 13, member A | 0.0359657 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0358769 |
| RACK1 | receptor for activated C kinase 1 | 0.0358526 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0355457 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0353656 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0351718 |
| KIF5B | kinesin family member 5B | 0.0351316 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0346417 |
| GSK3B | glycogen synthase kinase 3 beta | 0.034615 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0342994 |
| ABI1 | abl-interactor 1 | 0.034043 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0338279 |
| YAP1 | Yes-associated protein 1 | 0.033529 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0333441 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0324049 |
| ANKRD12 | ankyrin repeat domain 12 | 0.032035 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0319564 |
| DST | dystonin | 0.0315612 |
| RPL35A | ribosomal protein L35a | 0.0313995 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0313834 |
| SPAG9 | sperm associated antigen 9 | 0.0310648 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0303021 |
| TPI1 | triosephosphate isomerase 1 | 0.0300149 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0296976 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.029595 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0295504 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0294407 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0290569 |
| EGR1 | early growth response 1 | 0.0288091 |
| MATR3 | matrin 3 | 0.0281508 |
| EXOC4 | exocyst complex component 4 | 0.0281008 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MYO1E | myosin IE | -0.221192 |
| LMO7 | LIM domain 7 | -0.219708 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.162735 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.154878 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.149447 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.143612 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.136186 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.13154 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.108795 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.104311 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0988517 |
| CMIP | c-Maf inducing protein | -0.096285 |
| ATOSA | atos homolog A | -0.0940628 |
| SVIL | supervillin | -0.0908166 |
| ABHD17C | abhydrolase domain containing 17C | -0.0782597 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0717788 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0706239 |
| VCL | vinculin | -0.0673381 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0666706 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0657725 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0636353 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0631198 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0626175 |
| MUC16 | mucin 16, cell surface associated | -0.0625581 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.062305 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0592456 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0584596 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0574168 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0549061 |
| RBM47 | RNA binding motif protein 47 | -0.0544096 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.053981 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0525659 |
| RAD51B | RAD51 paralog B | -0.0517978 |
| ANXA2 | annexin A2 | -0.0505012 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0503865 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0502011 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0468332 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0463695 |
| FOXO1 | forkhead box O1 | -0.0463492 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0456842 |
| RIGI | RNA sensor RIG-I | -0.0450222 |
| MYO6 | myosin VI | -0.044613 |
| PAPOLA | poly(A) polymerase alpha | -0.0444706 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | -0.0436626 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0434547 |
| KYNU | kynureninase | -0.0433362 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0427538 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0425971 |
| LAMC2 | laminin, gamma 2 | -0.0424682 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0422374 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0419582 |
| STEAP4 | STEAP family member 4 | -0.0416116 |
| KRT17 | keratin 17, type I | -0.0412838 |
| FOXP1 | forkhead box P1 | -0.0408378 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.040592 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0404475 |
| TMEM165 | transmembrane protein 165 | -0.0395425 |
| EGFR | epidermal growth factor receptor | -0.0392567 |
| STK17A | serine/threonine kinase 17a | -0.0390167 |
| FNDC3A | fibronectin type III domain containing 3A | -0.038981 |
| TC2N | tandem C2 domains, nuclear | -0.0388441 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0385006 |
| TJP2 | tight junction protein 2 | -0.0378548 |
| RORA | RAR-related orphan receptor A | -0.0376858 |
| MRTFA | myocardin related transcription factor A | -0.0369476 |
| SQSTM1 | sequestosome 1 | -0.0365397 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0363538 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0363026 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0361759 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0351759 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0350039 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0347978 |
| AK1 | adenylate kinase 1 | -0.0347812 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0347429 |
| MORC3 | MORC family CW-type zinc finger 3 | -0.0342509 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0339989 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0336591 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0336159 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0335822 |
| RNF149 | ring finger protein 149 | -0.0334697 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.032952 |
| TJP1 | tight junction protein 1 | -0.0328971 |
| APP | amyloid beta (A4) precursor protein | -0.0325798 |
| FMNL2 | formin-like 2 | -0.0325517 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0319563 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0315894 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | -0.0315833 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0310553 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0308016 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0304339 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0302458 |
| MCL1 | myeloid cell leukemia 1 | -0.0297874 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0297718 |
| ATP11A | ATPase, class VI, type 11A | -0.0296508 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0292028 |
| MED13 | mediator complex subunit 13 | -0.0288764 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0281813 |
| FTO | fat mass and obesity associated | -0.0275959 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0273119 |
| USP34 | ubiquitin specific peptidase 34 | -0.0267618 |
