| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0686702 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0667612 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0626939 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0481752 |
| CD109 | CD109 molecule | 0.0480969 |
| TXNRD1 | thioredoxin reductase 1 | 0.0451181 |
| KYNU | kynureninase | 0.0441911 |
| EZR | ezrin | 0.0409922 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0403856 |
| TPM3 | tropomyosin 3 | 0.0365114 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0361419 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0353276 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0337509 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0335508 |
| NUP58 | nucleoporin 58 | 0.0316013 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0311358 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0309698 |
| MCL1 | myeloid cell leukemia 1 | 0.0302366 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0295935 |
| WDR43 | WD repeat domain 43 | 0.0293983 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0290561 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0290376 |
| RPLP0 | ribosomal protein, large, P0 | 0.0277696 |
| RPL3 | ribosomal protein L3 | 0.0277253 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0272887 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0271528 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0264862 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.026463 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0261256 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0258566 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0251104 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0250836 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0245129 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0244809 |
| RPL36A | ribosomal protein L36a | 0.0242129 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0242004 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0240735 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0235002 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0230604 |
| MATR3 | matrin 3 | 0.0228439 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0226614 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0225878 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0223146 |
| COL5A2 | collagen, type V, alpha 2 | 0.0222433 |
| FLNA | filamin A, alpha | 0.0221929 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0216251 |
| RPLP1 | ribosomal protein, large, P1 | 0.0208194 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0205767 |
| RBM39 | RNA binding motif protein 39 | 0.0205031 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0204065 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0203245 |
| FUS | FUS RNA binding protein | 0.0202403 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0197866 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.01961 |
| RPS21 | ribosomal protein S21 | 0.0195912 |
| TNPO1 | transportin 1 | 0.0195792 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0194736 |
| PCBP2 | poly(rC) binding protein 2 | 0.0192408 |
| ANXA5 | annexin A5 | 0.0190914 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0190247 |
| SET | SET nuclear proto-oncogene | 0.0189826 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0184763 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0184744 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0184436 |
| DENND4A | DENN/MADD domain containing 4A | 0.0182379 |
| CUL3 | cullin 3 | 0.0182251 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0180568 |
| ANLN | anillin, actin binding protein | 0.0178064 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0178008 |
| YBX1 | Y box binding protein 1 | 0.0176429 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0176016 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0175996 |
| GOLGA4 | golgin A4 | 0.0174657 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.01735 |
| CBX3 | chromobox homolog 3 | 0.0171624 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0171192 |
| RPS4X | ribosomal protein S4, X-linked | 0.0170013 |
| RPS24 | ribosomal protein S24 | 0.0169307 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.016929 |
| KLC1 | kinesin light chain 1 | 0.0166789 |
| CENPF | centromere protein F, 350/400kDa | 0.0163574 |
| TSC22D2 | TSC22 domain family, member 2 | 0.016241 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.016213 |
| ATP13A3 | ATPase type 13A3 | 0.0161219 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.016086 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.016044 |
| NEK7 | NIMA-related kinase 7 | 0.0160153 |
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 0.0158606 |
| FAM168B | family with sequence similarity 168, member B | 0.015848 |
| PHIP | pleckstrin homology domain interacting protein | 0.0157808 |
| IPO7 | importin 7 | 0.0157071 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.01568 |
| RUNX1 | runt-related transcription factor 1 | 0.0154202 |
| RPL26 | ribosomal protein L26 | 0.0153883 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0153878 |
| DTNA | dystrobrevin, alpha | 0.0153685 |
| RTN4 | reticulon 4 | 0.0153494 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.015069 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0150338 |
| ECT2 | epithelial cell transforming 2 | 0.0150115 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.216214 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.133186 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.118878 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.104703 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0991099 |
| EFNA5 | ephrin-A5 | -0.0923013 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.083182 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0822599 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0706877 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0704918 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0682258 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0681549 |
| MT2A | metallothionein 2A | -0.0653006 |
| TMSB10 | thymosin beta 10 | -0.062624 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0541443 |
| SMYD3 | SET and MYND domain containing 3 | -0.0538015 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0513771 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0493007 |
| PDE7B | phosphodiesterase 7B | -0.0467197 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.044784 |
| PGK1 | phosphoglycerate kinase 1 | -0.0447046 |
| AUTS2 | autism susceptibility candidate 2 | -0.0435233 |
| CANX | calnexin | -0.0430072 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0428719 |
| FTL | ferritin, light polypeptide | -0.0408112 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0407022 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0392309 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0371871 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0369201 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0364515 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0362507 |
| STC1 | stanniocalcin 1 | -0.0358324 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0341487 |
| PTMA | prothymosin, alpha | -0.0338071 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0337677 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0337542 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0328434 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0313 |
| NCKAP5 | NCK-associated protein 5 | -0.0301889 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0297567 |
| PYGL | phosphorylase, glycogen, liver | -0.0295465 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0286682 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0282806 |
| RGS2 | regulator of G-protein signaling 2 | -0.0282201 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0275046 |
| LDHA | lactate dehydrogenase A | -0.0274916 |
| RPS3 | ribosomal protein S3 | -0.0274197 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0266514 |
| EPHA4 | EPH receptor A4 | -0.0255007 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0253653 |
| NCAM2 | neural cell adhesion molecule 2 | -0.025352 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0251767 |
| PTGR1 | prostaglandin reductase 1 | -0.0250716 |
| RTN1 | reticulon 1 | -0.0248983 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0244593 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0244571 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0242279 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.0240143 |
| MYOF | myoferlin | -0.0237622 |
| PCBP3 | poly(rC) binding protein 3 | -0.0236305 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.023439 |
| DST | dystonin | -0.0233908 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0232997 |
| B2M | beta-2-microglobulin | -0.0229815 |
| RAI1 | retinoic acid induced 1 | -0.0226293 |
| HDAC8 | histone deacetylase 8 | -0.0224244 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0223133 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0217349 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0207324 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0206581 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0206477 |
| TBC1D19 | TBC1 domain family, member 19 | -0.0205814 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0205303 |
| CHL1 | cell adhesion molecule L1-like | -0.020417 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0202199 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0198774 |
| RACK1 | receptor for activated C kinase 1 | -0.0198262 |
| S100A6 | S100 calcium binding protein A6 | -0.0197906 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0197462 |
| ESM1 | endothelial cell-specific molecule 1 | -0.0196428 |
| EHBP1 | EH domain binding protein 1 | -0.0196138 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0194909 |
| PAPPA2 | pappalysin 2 | -0.0194888 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0194698 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.018952 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.018948 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0185917 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0185396 |
| CCDC6 | coiled-coil domain containing 6 | -0.0184962 |
| SRPK2 | SRSF protein kinase 2 | -0.0182983 |
| ENO1 | enolase 1, (alpha) | -0.0181449 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0181046 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0180288 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0180135 |
| RPL18 | ribosomal protein L18 | -0.0178491 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0178381 |
| NBEAL1 | neurobeachin-like 1 | -0.0177925 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0176736 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0176133 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0172782 |
