| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAV2 | neuron navigator 2 | 0.107832 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.103302 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.101204 |
| MAP1B | microtubule-associated protein 1B | 0.0957751 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0892701 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0880302 |
| DST | dystonin | 0.0872996 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0830048 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0817214 |
| GLG1 | golgi glycoprotein 1 | 0.0811329 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0798773 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0775777 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0745512 |
| PDE10A | phosphodiesterase 10A | 0.0725821 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0723584 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0713323 |
| PGK1 | phosphoglycerate kinase 1 | 0.0704786 |
| USP3 | ubiquitin specific peptidase 3 | 0.0696744 |
| RBM25 | RNA binding motif protein 25 | 0.0696574 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0687191 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.068472 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0683107 |
| MATR3 | matrin 3 | 0.0679646 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0675491 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0652098 |
| MED13L | mediator complex subunit 13-like | 0.0631253 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0621341 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0599728 |
| FLNB | filamin B, beta | 0.0595786 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0585957 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0579987 |
| ENO1 | enolase 1, (alpha) | 0.0579965 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0554412 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0539477 |
| MED13 | mediator complex subunit 13 | 0.0520786 |
| KIAA1217 | KIAA1217 | 0.0520501 |
| ATXN1 | ataxin 1 | 0.0517576 |
| FN1 | fibronectin 1 | 0.0508374 |
| GNAS | GNAS complex locus | 0.0498151 |
| TJP1 | tight junction protein 1 | 0.0492444 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0490253 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0487974 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0486748 |
| ACTG1 | actin gamma 1 | 0.048262 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0475161 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0459908 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0454677 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0435313 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0434761 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0431181 |
| OGA | O-GlcNAcase | 0.0415288 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0411266 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.040563 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0403614 |
| RPL23 | ribosomal protein L23 | 0.0403053 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0402513 |
| COL6A3 | collagen, type VI, alpha 3 | 0.037896 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0355213 |
| RBM39 | RNA binding motif protein 39 | 0.0353398 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0336277 |
| CCNY | cyclin Y | 0.0334294 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0331435 |
| RNF213 | ring finger protein 213 | 0.0329051 |
| VCL | vinculin | 0.0319086 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0316878 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0315054 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.030702 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0303505 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0303137 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0301581 |
| RACK1 | receptor for activated C kinase 1 | 0.0296185 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0290181 |
| CALU | calumenin | 0.0288182 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0286505 |
| HELZ | helicase with zinc finger | 0.0282492 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0276904 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0272298 |
| SETD5 | SET domain containing 5 | 0.0269361 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0253118 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0239587 |
| BPTF | bromodomain PHD finger transcription factor | 0.0235478 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0234081 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0232281 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0231134 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.023001 |
| TOP1 | topoisomerase (DNA) I | 0.0220985 |
| RPS27A | ribosomal protein S27a | 0.0215774 |
| CUL3 | cullin 3 | 0.0215531 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0211773 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0210728 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0206725 |
| HMGA1 | high mobility group AT-hook 1 | 0.0203789 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0201958 |
| STC1 | stanniocalcin 1 | 0.0193972 |
| RPL12 | ribosomal protein L12 | 0.0187067 |
| RLF | rearranged L-myc fusion | 0.0177777 |
| PDE8A | phosphodiesterase 8A | 0.0174093 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0171561 |
| PRELID2 | PRELI domain containing 2 | 0.0170252 |
| WASF2 | WAS protein family, member 2 | 0.0169057 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.249254 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.125845 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109015 |
| MYO1E | myosin IE | -0.0985019 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0954068 |
| IGF2 | insulin-like growth factor 2 | -0.0872338 |
| RPS3 | ribosomal protein S3 | -0.0813977 |
| SMYD3 | SET and MYND domain containing 3 | -0.071763 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0712694 |
| PRKCA | protein kinase C, alpha | -0.0694909 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0677426 |
| ANXA2 | annexin A2 | -0.0636129 |
| MCL1 | myeloid cell leukemia 1 | -0.0623598 |
| FTL | ferritin, light polypeptide | -0.061316 |
| RPLP1 | ribosomal protein, large, P1 | -0.0606497 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0591825 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0585499 |
| SBF2 | SET binding factor 2 | -0.0571767 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0571154 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0570128 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0543732 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0521634 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0507606 |
| RORA | RAR-related orphan receptor A | -0.0501446 |
| TENM3 | teneurin transmembrane protein 3 | -0.0491177 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0489933 |
| RAB10 | RAB10, member RAS oncogene family | -0.0489215 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0474937 |
| TPD52 | tumor protein D52 | -0.0439867 |
| LDHA | lactate dehydrogenase A | -0.043534 |
| NFIA | nuclear factor I/A | -0.0428818 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0411373 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0407248 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0403438 |
| PCM1 | pericentriolar material 1 | -0.0402505 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0397807 |
| RUNX1 | runt-related transcription factor 1 | -0.0389349 |
| SLTM | SAFB-like, transcription modulator | -0.0385016 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0383999 |
| MT2A | metallothionein 2A | -0.0381489 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0359927 |
| RPS8 | ribosomal protein S8 | -0.0353345 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0352988 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0352478 |
| RPS29 | ribosomal protein S29 | -0.0350963 |
| FRY | furry homolog (Drosophila) | -0.0349086 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0345615 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.034555 |
| TAOK1 | TAO kinase 1 | -0.0340955 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0338571 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0333298 |
| MYO1D | myosin ID | -0.0329133 |
| RPL5 | ribosomal protein L5 | -0.0322909 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0317253 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0314932 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0312417 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0310074 |
| GPC6 | glypican 6 | -0.0308481 |
| PTMA | prothymosin, alpha | -0.0304421 |
| ARRDC3 | arrestin domain containing 3 | -0.030261 |
| TMSB10 | thymosin beta 10 | -0.0300688 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0299311 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0298728 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.029672 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0295612 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0295028 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0289858 |
| SPAG9 | sperm associated antigen 9 | -0.0286702 |
| RPL4 | ribosomal protein L4 | -0.0285047 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0281942 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0280867 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0279161 |
| PKM | pyruvate kinase, muscle | -0.0267522 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0265096 |
| KYNU | kynureninase | -0.0262637 |
| B2M | beta-2-microglobulin | -0.0262521 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0261809 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.026157 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0261569 |
| HLA-B | major histocompatibility complex, class I, B | -0.0259504 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0253368 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0252607 |
| RBMX | RNA binding motif protein, X-linked | -0.0251196 |
| RPL31 | ribosomal protein L31 | -0.0245766 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0245644 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0242177 |
| SQSTM1 | sequestosome 1 | -0.0241821 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0239648 |
| SP100 | SP100 nuclear antigen | -0.0235828 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.023523 |
| NGLY1 | N-glycanase 1 | -0.0228622 |
| VIM | vimentin | -0.0228558 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -0.0228123 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0225686 |
| EFNA5 | ephrin-A5 | -0.0221757 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0218824 |
| RAD51B | RAD51 paralog B | -0.0209871 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0208781 |
| INTS6 | integrator complex subunit 6 | -0.020773 |
| MAP4 | microtubule-associated protein 4 | -0.0200451 |
