| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.0280032 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0235955 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0191096 |
| RACK1 | receptor for activated C kinase 1 | 0.0174895 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0172256 |
| TENM3 | teneurin transmembrane protein 3 | 0.0165267 |
| CDC73 | cell division cycle 73 | 0.0164167 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0161825 |
| FLNA | filamin A, alpha | 0.0158931 |
| TLK2 | tousled-like kinase 2 | 0.0148398 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0147783 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0144871 |
| RPL3 | ribosomal protein L3 | 0.0143822 |
| TENM2 | teneurin transmembrane protein 2 | 0.0142606 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0141898 |
| SPAG9 | sperm associated antigen 9 | 0.0139847 |
| H1-5 | H1.5 linker histone, cluster member | 0.0138756 |
| PRELID2 | PRELI domain containing 2 | 0.0134638 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0132285 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0130012 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.012969 |
| ZNF608 | zinc finger protein 608 | 0.0129614 |
| SHROOM3 | shroom family member 3 | 0.0126234 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0124161 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.012249 |
| NTM | neurotrimin | 0.012135 |
| CENPF | centromere protein F, 350/400kDa | 0.0120884 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | 0.0118082 |
| LCLAT1 | lysocardiolipin acyltransferase 1 | 0.0117671 |
| MYO10 | myosin X | 0.0115994 |
| RPS26 | ribosomal protein S26 | 0.0115559 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0115182 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.0114115 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0110612 |
| EFNA5 | ephrin-A5 | 0.0109551 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.0108819 |
| MPG | N-methylpurine-DNA glycosylase | 0.0107621 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.0106694 |
| LAMP1 | lysosomal-associated membrane protein 1 | 0.0105967 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0102151 |
| ANXA1 | annexin A1 | 0.0101026 |
| PDE10A | phosphodiesterase 10A | 0.0100447 |
| C7ORF57 | chromosome 7 open reading frame 57 | 0.010003 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.00993847 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha | 0.00993062 |
| KIF4A | kinesin family member 4A | 0.00984796 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.00970288 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.0096755 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.00963939 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.00952425 |
| HDAC8 | histone deacetylase 8 | 0.00948851 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.00947998 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | 0.00943683 |
| PHF14 | PHD finger protein 14 | 0.00943363 |
| MYO9A | myosin IXA | 0.00943056 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.00939288 |
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.00936262 |
| PRKD1 | protein kinase D1 | 0.00929162 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | 0.00925135 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.00924449 |
| ANXA5 | annexin A5 | 0.00920792 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.00920624 |
| TENT4B | terminal nucleotidyltransferase 4B | 0.0091732 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.00915855 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.00915568 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00904972 |
| GSN | gelsolin | 0.00903765 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0090208 |
| UBAP2L | ubiquitin associated protein 2-like | 0.00898498 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | 0.00898276 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.00887151 |
| PREPL | prolyl endopeptidase-like | 0.00881752 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.00879682 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.00870108 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.00866299 |
| ZNF385D | zinc finger protein 385D | 0.00865478 |
| NAV3 | neuron navigator 3 | 0.00865411 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.00859657 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.00857708 |
| SATB2 | SATB homeobox 2 | 0.00852 |
| TLK1 | tousled-like kinase 1 | 0.00848828 |
| MT2A | metallothionein 2A | 0.00845605 |
| CGN | cingulin | 0.00841722 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 0.00841027 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | 0.00840932 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.00840808 |
| RPL13A | ribosomal protein L13a | 0.00835651 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00833537 |
| CLINT1 | clathrin interactor 1 | 0.00828109 |
| FBXO34 | F-box protein 34 | 0.00825947 |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 | 0.00824001 |
| KATNBL1 | katanin p80 subunit B-like 1 | 0.00823648 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00818072 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0081749 |
| SERINC1 | serine incorporator 1 | 0.00817415 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00816786 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.00815584 |
| ZNF217 | zinc finger protein 217 | 0.00815437 |
| RPS15A | ribosomal protein S15a | 0.00811868 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.00811696 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.195945 |
| TMSB10 | thymosin beta 10 | -0.127731 |
| PTMA | prothymosin, alpha | -0.124462 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0802015 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0746063 |
| RPS16 | ribosomal protein S16 | -0.0738962 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0674733 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0636793 |
| UBC | ubiquitin C | -0.058784 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0572699 |
| RPS27A | ribosomal protein S27a | -0.0570924 |
| ACTG1 | actin gamma 1 | -0.0537407 |
| AHNAK | AHNAK nucleoprotein | -0.0520216 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0519818 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0486123 |
| ENO1 | enolase 1, (alpha) | -0.0477307 |
| POTEF | POTE ankyrin domain family, member F | -0.044742 |
| COL3A1 | collagen, type III, alpha 1 | -0.0442429 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0441817 |
| THBS1 | thrombospondin 1 | -0.0431929 |
| RPS8 | ribosomal protein S8 | -0.0399149 |
| COL1A2 | collagen, type I, alpha 2 | -0.0397616 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0396388 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0389196 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0379884 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0377598 |
| PEG10 | paternally expressed 10 | -0.0370529 |
| COL5A2 | collagen, type V, alpha 2 | -0.0369678 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0362447 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0358809 |
| RPL5 | ribosomal protein L5 | -0.0355682 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0351937 |
| S100A10 | S100 calcium binding protein A10 | -0.0338938 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0333728 |
| PCBP2 | poly(rC) binding protein 2 | -0.0320949 |
| PGK1 | phosphoglycerate kinase 1 | -0.0315526 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0315258 |
| CALU | calumenin | -0.0314762 |
| PHIP | pleckstrin homology domain interacting protein | -0.0308484 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0302586 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0301006 |
| RPLP1 | ribosomal protein, large, P1 | -0.0293859 |
| APP | amyloid beta (A4) precursor protein | -0.0293509 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0291036 |
| RPS6 | ribosomal protein S6 | -0.0290498 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0281366 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0277226 |
| ANXA2 | annexin A2 | -0.0268843 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0268595 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0266858 |
| SET | SET nuclear proto-oncogene | -0.0265924 |
| RPS25 | ribosomal protein S25 | -0.0265921 |
| RTN4 | reticulon 4 | -0.026248 |
| RPL23 | ribosomal protein L23 | -0.0255497 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0253352 |
| HMGB2 | high mobility group box 2 | -0.0248508 |
| ACTN4 | actinin, alpha 4 | -0.0242748 |
| CALR | calreticulin | -0.0239149 |
| LDHA | lactate dehydrogenase A | -0.023608 |
| EMP1 | epithelial membrane protein 1 | -0.0233291 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0231282 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0228926 |
| YAP1 | Yes-associated protein 1 | -0.0228154 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0226643 |
| PFN1 | profilin 1 | -0.0226386 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0224878 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0224372 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0222595 |
| ITGAV | integrin, alpha V | -0.022226 |
| HMGB1 | high mobility group box 1 | -0.0221747 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0220825 |
| PCDH9 | protocadherin 9 | -0.0220648 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0219982 |
| SEPTIN7 | septin 7 | -0.0219751 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0218461 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0217372 |
| JUN | jun proto-oncogene | -0.0216344 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0215892 |
| GNAS | GNAS complex locus | -0.021429 |
| RPS21 | ribosomal protein S21 | -0.0214249 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0210706 |
| RPL32 | ribosomal protein L32 | -0.0210585 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0209393 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0208917 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0207884 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0207765 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0206872 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0206201 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0205841 |
| RHEB | Ras homolog enriched in brain | -0.0204305 |
| TUBA1B | tubulin, alpha 1b | -0.0203023 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0199829 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0197282 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.019697 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0195973 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0189757 |
| RPS24 | ribosomal protein S24 | -0.0188949 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0188369 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0186189 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0186169 |
