| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Levobupivacaine (hydrochloride)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.107207 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0756228 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0678117 |
| RACK1 | receptor for activated C kinase 1 | 0.0644702 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0622348 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0555392 |
| SEPTIN9 | septin 9 | 0.0546696 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0508079 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0492009 |
| SMAD3 | SMAD family member 3 | 0.045166 |
| ACTN4 | actinin, alpha 4 | 0.0445713 |
| YBX1 | Y box binding protein 1 | 0.043582 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0416894 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0399249 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0392311 |
| TPM3 | tropomyosin 3 | 0.0388494 |
| EFNA5 | ephrin-A5 | 0.0385677 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0377116 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0362707 |
| DST | dystonin | 0.0346454 |
| SMYD3 | SET and MYND domain containing 3 | 0.0345234 |
| CDK19 | cyclin-dependent kinase 19 | 0.0326187 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0323092 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0319616 |
| MED13L | mediator complex subunit 13-like | 0.0319412 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0307597 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0299175 |
| SET | SET nuclear proto-oncogene | 0.0297591 |
| CARD18 | caspase recruitment domain family, member 18 | 0.0295217 |
| PLEC | plectin | 0.0292693 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0289536 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0284732 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0274454 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0270753 |
| AFAP1 | actin filament associated protein 1 | 0.0267636 |
| PTEN | phosphatase and tensin homolog | 0.0266094 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0257197 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0256056 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0252927 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0252779 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0252614 |
| MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | 0.0252259 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0251211 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0249369 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0248192 |
| RPL3 | ribosomal protein L3 | 0.0246769 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0236768 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0232425 |
| FHL2 | four and a half LIM domains 2 | 0.0229757 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0223871 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0221473 |
| THOC2 | THO complex 2 | 0.0219543 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0218819 |
| FLNA | filamin A, alpha | 0.0217806 |
| ARRDC3 | arrestin domain containing 3 | 0.0216738 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0216726 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0211805 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0209411 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0208971 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | 0.0208034 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0207998 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0207919 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0205393 |
| MSN | moesin | 0.0203248 |
| UTRN | utrophin | 0.020231 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0201105 |
| DSTN | destrin (actin depolymerizing factor) | 0.02005 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0197435 |
| ATM | ATM serine/threonine kinase | 0.0196764 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0193039 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0191944 |
| PHF14 | PHD finger protein 14 | 0.0189985 |
| ZNF638 | zinc finger protein 638 | 0.0189533 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0186986 |
| XPO1 | exportin 1 | 0.0185355 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0183574 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | 0.0182861 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0177689 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0177499 |
| NFX1 | nuclear transcription factor, X-box binding 1 | 0.017701 |
| DNHD1 | dynein heavy chain domain 1 | 0.0176259 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0175601 |
| NRDC | nardilysin convertase | 0.0175169 |
| ZBTB44 | zinc finger and BTB domain containing 44 | 0.0174168 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.017415 |
| EGFR | epidermal growth factor receptor | 0.0173178 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0172622 |
| BMP6 | bone morphogenetic protein 6 | 0.0172119 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0171566 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0170824 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0169791 |
| PANK3 | pantothenate kinase 3 | 0.0169023 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0166464 |
| ATXN1 | ataxin 1 | 0.0165448 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0165135 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0164887 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | 0.01633 |
| RPS4X | ribosomal protein S4, X-linked | 0.0160734 |
| ZFP36 | ZFP36 ring finger protein | 0.0160402 |
| FAM120B | family with sequence similarity 120B | 0.0160381 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.223201 |
| PTMA | prothymosin, alpha | -0.192692 |
| RPS16 | ribosomal protein S16 | -0.191847 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.125366 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.124731 |
| TMSB10 | thymosin beta 10 | -0.106317 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0998102 |
| AHNAK | AHNAK nucleoprotein | -0.0695819 |
| FTL | ferritin, light polypeptide | -0.0640536 |
| RPL35A | ribosomal protein L35a | -0.0515771 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0479201 |
| SPAG9 | sperm associated antigen 9 | -0.0435748 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0425868 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0420968 |
| TMEM123 | transmembrane protein 123 | -0.0418565 |
| RPLP2 | ribosomal protein, large, P2 | -0.0415167 |
| H1-0 | H1.0 linker histone | -0.0402849 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0402262 |
| RPS3 | ribosomal protein S3 | -0.0399625 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0388716 |
| RPS24 | ribosomal protein S24 | -0.0387537 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0385419 |
| CANX | calnexin | -0.0378428 |
| CTSD | cathepsin D | -0.0372192 |
| PGK1 | phosphoglycerate kinase 1 | -0.0348518 |
| MORF4L2 | mortality factor 4 like 2 | -0.0340324 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0336951 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0329033 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0318983 |
| ENO1 | enolase 1, (alpha) | -0.0318586 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0315955 |
| MT2A | metallothionein 2A | -0.0315069 |
| RPS25 | ribosomal protein S25 | -0.0306719 |
| S100A6 | S100 calcium binding protein A6 | -0.0306433 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0290994 |
| RPS6 | ribosomal protein S6 | -0.0286032 |
| RPLP0 | ribosomal protein, large, P0 | -0.0285071 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0284492 |
| RTN4 | reticulon 4 | -0.0276672 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0260512 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0260234 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0257001 |
| ADM | adrenomedullin | -0.0255737 |
| RPS27A | ribosomal protein S27a | -0.0254631 |
| CD44 | CD44 molecule (Indian blood group) | -0.0254567 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0250439 |
| PLAU | plasminogen activator, urokinase | -0.0250338 |
| RPLP1 | ribosomal protein, large, P1 | -0.024939 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0244376 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0240662 |
| RPL38 | ribosomal protein L38 | -0.0238959 |
| FMNL2 | formin-like 2 | -0.0237929 |
| WASF2 | WAS protein family, member 2 | -0.0236847 |
| DIAPH2 | diaphanous-related formin 2 | -0.0233266 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0233012 |
| ANLN | anillin, actin binding protein | -0.0231958 |
| HMGB1 | high mobility group box 1 | -0.0224447 |
| WDR45B | WD repeat domain 45B | -0.0215513 |
| RPS10 | ribosomal protein S10 | -0.0213826 |
| RNF220 | ring finger protein 220 | -0.0213693 |
| TAOK1 | TAO kinase 1 | -0.0213342 |
| USP3 | ubiquitin specific peptidase 3 | -0.0211844 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0210869 |
| PFN1 | profilin 1 | -0.0209578 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0204586 |
| ZNF546 | zinc finger protein 546 | -0.0203249 |
| FNIP1 | folliculin interacting protein 1 | -0.0200924 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.0200597 |
| CD109 | CD109 molecule | -0.0200558 |
| RPS13 | ribosomal protein S13 | -0.0197283 |
| NAV2 | neuron navigator 2 | -0.0196944 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0195092 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0194255 |
| RPL31 | ribosomal protein L31 | -0.0193668 |
| TPM1 | tropomyosin 1 (alpha) | -0.0193408 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0192178 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0191795 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0191707 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0190973 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0190415 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0189978 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0188298 |
| PKM | pyruvate kinase, muscle | -0.018764 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0186599 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.018644 |
| RPL32 | ribosomal protein L32 | -0.0186016 |
| RPS29 | ribosomal protein S29 | -0.0185745 |
| MAP4 | microtubule-associated protein 4 | -0.0184037 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0182436 |
| SQSTM1 | sequestosome 1 | -0.0181585 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0178073 |
| ATG7 | autophagy related 7 | -0.0177725 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0177556 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0177421 |
| RPS14 | ribosomal protein S14 | -0.0176876 |
| S100A9 | S100 calcium binding protein A9 | -0.0176621 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.017621 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0175707 |
| RPL19 | ribosomal protein L19 | -0.0175437 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0174897 |
