| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VGF | VGF nerve growth factor inducible | 0.0649065 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0631573 |
| NDRG1 | N-myc downstream regulated 1 | 0.06169 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.053855 |
| TPM3 | tropomyosin 3 | 0.0509035 |
| FAT1 | FAT atypical cadherin 1 | 0.0503322 |
| NUP58 | nucleoporin 58 | 0.0431529 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0407215 |
| PDE10A | phosphodiesterase 10A | 0.0398726 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0361074 |
| RPL3 | ribosomal protein L3 | 0.03498 |
| XPO1 | exportin 1 | 0.0348712 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0337523 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.033721 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0306489 |
| VEGFA | vascular endothelial growth factor A | 0.0302033 |
| CENPF | centromere protein F, 350/400kDa | 0.0300615 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0274463 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.026541 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0265011 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0262853 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0261951 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0260649 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0255785 |
| CCNL1 | cyclin L1 | 0.0243917 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0240898 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0239605 |
| SET | SET nuclear proto-oncogene | 0.0239411 |
| PCBP2 | poly(rC) binding protein 2 | 0.0237859 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0235657 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0231443 |
| RNF145 | ring finger protein 145 | 0.0229343 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0227814 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0227215 |
| PNN | pinin, desmosome associated protein | 0.0226207 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0218337 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0217586 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0216785 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.021267 |
| CD24 | CD24 molecule | 0.0210093 |
| WDR45B | WD repeat domain 45B | 0.020885 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0208508 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0208295 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0207496 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0206823 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0206505 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.020596 |
| ZNF292 | zinc finger protein 292 | 0.0204834 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0204635 |
| ITGAV | integrin, alpha V | 0.0198515 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0197519 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0196687 |
| HMGB3 | high mobility group box 3 | 0.0196257 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0194718 |
| HDGF | hepatoma-derived growth factor | 0.0194563 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0192557 |
| MTMR7 | myotubularin related protein 7 | 0.0189949 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0189809 |
| CA8 | carbonic anhydrase VIII | 0.0189225 |
| POTEF | POTE ankyrin domain family, member F | 0.0188932 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0187657 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0185542 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0183071 |
| PTK2 | protein tyrosine kinase 2 | 0.0181949 |
| SPAG5 | sperm associated antigen 5 | 0.0181507 |
| MATR3 | matrin 3 | 0.018116 |
| RANBP2 | RAN binding protein 2 | 0.0180615 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0178949 |
| GRAMD4 | GRAM domain containing 4 | 0.0178455 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0175841 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0174584 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0174017 |
| KLHL24 | kelch-like family member 24 | 0.0173074 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.017216 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0171503 |
| NFIB | nuclear factor I/B | 0.0170711 |
| YBX1 | Y box binding protein 1 | 0.017029 |
| CHKA | choline kinase alpha | 0.0169507 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0168364 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0167988 |
| ARRDC3 | arrestin domain containing 3 | 0.0164056 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0163919 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0163807 |
| LMNB1 | lamin B1 | 0.016255 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0162044 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.0161992 |
| CDK8 | cyclin-dependent kinase 8 | 0.0161943 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.016095 |
| RAB6A | RAB6A, member RAS oncogene family | 0.016092 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0160908 |
| RACK1 | receptor for activated C kinase 1 | 0.0160748 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0160186 |
| ECT2 | epithelial cell transforming 2 | 0.0159734 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 | 0.0158615 |
| KLHL2 | kelch-like family member 2 | 0.0158199 |
| USP22 | ubiquitin specific peptidase 22 | 0.0157681 |
| ANLN | anillin, actin binding protein | 0.0157397 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0156825 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0156204 |
| DSTN | destrin (actin depolymerizing factor) | 0.0155861 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | -0.142421 |
| PTMA | prothymosin, alpha | -0.140005 |
| GPC6 | glypican 6 | -0.114037 |
| NRG1 | neuregulin 1 | -0.11018 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0858509 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0854681 |
| ACTG1 | actin gamma 1 | -0.0803702 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.07706 |
| CALCA | calcitonin-related polypeptide alpha | -0.0735231 |
| SNTG1 | syntrophin, gamma 1 | -0.0703353 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0635796 |
| SMYD3 | SET and MYND domain containing 3 | -0.0627059 |
| STC1 | stanniocalcin 1 | -0.0615806 |
| GPC5 | glypican 5 | -0.0551872 |
| FTL | ferritin, light polypeptide | -0.0525465 |
| RPS21 | ribosomal protein S21 | -0.0512433 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0510492 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0508787 |
| INHBA | inhibin, beta A | -0.0503426 |
| RPS3 | ribosomal protein S3 | -0.0502758 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0480967 |
| MT2A | metallothionein 2A | -0.0474514 |
| NCKAP5 | NCK-associated protein 5 | -0.047422 |
| PTCHD4 | patched domain containing 4 | -0.04721 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0462144 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0456955 |
| RPLP1 | ribosomal protein, large, P1 | -0.0445983 |
| RPL37A | ribosomal protein L37a | -0.0432443 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0431386 |
| RPS8 | ribosomal protein S8 | -0.0427481 |
| PEG10 | paternally expressed 10 | -0.0420289 |
| TENM1 | teneurin transmembrane protein 1 | -0.0420165 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0418735 |
| SCG2 | secretogranin II | -0.0414445 |
| RPS6 | ribosomal protein S6 | -0.0412663 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0410829 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0410375 |
| NBEA | neurobeachin | -0.0408328 |
| RPS27A | ribosomal protein S27a | -0.040665 |
| SYT1 | synaptotagmin I | -0.0394967 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0394824 |
| FGF14 | fibroblast growth factor 14 | -0.0391939 |
| RORA | RAR-related orphan receptor A | -0.0382734 |
| KIF26B | kinesin family member 26B | -0.0381761 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0381147 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0381132 |
| ZFHX3 | zinc finger homeobox 3 | -0.0378475 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0376966 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0373306 |
| TOX | thymocyte selection-associated high mobility group box | -0.0369768 |
| CNKSR3 | CNKSR family member 3 | -0.0363595 |
| RPL38 | ribosomal protein L38 | -0.0357409 |
| TMSB10 | thymosin beta 10 | -0.0344945 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0344811 |
| ZNF804A | zinc finger protein 804A | -0.0341705 |
| RIGI | RNA sensor RIG-I | -0.0341053 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0339904 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | -0.033974 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0332915 |
| RPL26 | ribosomal protein L26 | -0.0332407 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0331281 |
| RPL35 | ribosomal protein L35 | -0.0323559 |
| GNAS | GNAS complex locus | -0.0321393 |
| CHGA | chromogranin A | -0.0321373 |
| RPL37 | ribosomal protein L37 | -0.0317207 |
| RNF213 | ring finger protein 213 | -0.0314727 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0313572 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0312371 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0311554 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0311372 |
| KLHL29 | kelch-like family member 29 | -0.0311063 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0311049 |
| RPL11 | ribosomal protein L11 | -0.0310727 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0309771 |
| SP100 | SP100 nuclear antigen | -0.030609 |
| PCDH9 | protocadherin 9 | -0.030171 |
| CANX | calnexin | -0.0301196 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0300954 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -0.0300518 |
| RRBP1 | ribosome binding protein 1 | -0.0294199 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0294131 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | -0.0293772 |
| EFNA5 | ephrin-A5 | -0.0289365 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0288877 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0288428 |
| ESRRG | estrogen-related receptor gamma | -0.0281589 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0280541 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | -0.0279208 |
| MX2 | MX dynamin-like GTPase 2 | -0.0276923 |
| NINL | ninein-like | -0.0275826 |
| ASIC2 | acid sensing (proton gated) ion channel 2 | -0.0274836 |
| EPHA6 | EPH receptor A6 | -0.0271754 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0270501 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.0265174 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0264977 |
| S100A9 | S100 calcium binding protein A9 | -0.0260634 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0259711 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0258156 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0256366 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0255577 |
