| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.0950759 |
| FLNB | filamin B, beta | 0.0822877 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0707188 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0564399 |
| RPL3 | ribosomal protein L3 | 0.0465365 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0446721 |
| TXNRD1 | thioredoxin reductase 1 | 0.0412601 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0401842 |
| PRELID2 | PRELI domain containing 2 | 0.0381379 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0359737 |
| SBF2 | SET binding factor 2 | 0.0357229 |
| DUSP4 | dual specificity phosphatase 4 | 0.034435 |
| NBAS | neuroblastoma amplified sequence | 0.0344182 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.034332 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0341964 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0341834 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0334097 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0319461 |
| EZR | ezrin | 0.0309672 |
| SMYD3 | SET and MYND domain containing 3 | 0.0306377 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0291025 |
| GOLGA4 | golgin A4 | 0.0288863 |
| RHBDD1 | rhomboid domain containing 1 | 0.0285637 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0282552 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0282478 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0274245 |
| ANK2 | ankyrin 2, neuronal | 0.0261255 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0260383 |
| PYGB | phosphorylase, glycogen; brain | 0.0255021 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0252327 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0243066 |
| ECT2 | epithelial cell transforming 2 | 0.0242749 |
| NUP58 | nucleoporin 58 | 0.0242647 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0240435 |
| SRPK2 | SRSF protein kinase 2 | 0.023881 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0232893 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0229978 |
| EFNA5 | ephrin-A5 | 0.0227792 |
| CD47 | CD47 molecule | 0.0223866 |
| NCKAP1 | NCK-associated protein 1 | 0.0220214 |
| KLC1 | kinesin light chain 1 | 0.0219087 |
| HDAC9 | histone deacetylase 9 | 0.0217053 |
| VCL | vinculin | 0.0215605 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0213219 |
| TMEM65 | transmembrane protein 65 | 0.021193 |
| TMSB4X | thymosin beta 4, X-linked | 0.0211329 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0209684 |
| RBM39 | RNA binding motif protein 39 | 0.0209199 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0209111 |
| TMEM41B | transmembrane protein 41B | 0.0208324 |
| PTEN | phosphatase and tensin homolog | 0.0206039 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.020569 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.020359 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | 0.020358 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0201321 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0200633 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0199152 |
| STAG2 | stromal antigen 2 | 0.0196226 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.019593 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0193029 |
| USP34 | ubiquitin specific peptidase 34 | 0.0192052 |
| YEATS2 | YEATS domain containing 2 | 0.0190281 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0188622 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0186377 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0184636 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0184534 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0183909 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0179483 |
| ATP13A3 | ATPase type 13A3 | 0.0178979 |
| PLXNA1 | plexin A1 | 0.0178863 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0178686 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0177799 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0177438 |
| ZNF148 | zinc finger protein 148 | 0.0176947 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0176584 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0174426 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0174275 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0172176 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0172166 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0172022 |
| EP300 | E1A binding protein p300 | 0.0171358 |
| RBM25 | RNA binding motif protein 25 | 0.0170983 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0170486 |
| PLPP3 | phospholipid phosphatase 3 | 0.0169254 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0168678 |
| DENND1A | DENN/MADD domain containing 1A | 0.0168618 |
| EWSR1 | EWS RNA-binding protein 1 | 0.016794 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0167029 |
| TPD52 | tumor protein D52 | 0.0166873 |
| LOXL3 | lysyl oxidase-like 3 | 0.0166096 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0165998 |
| RHOA | ras homolog family member A | 0.0165456 |
| RBM33 | RNA binding motif protein 33 | 0.0165203 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0164328 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0163247 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0162179 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0160285 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0159468 |
| RUNX1 | runt-related transcription factor 1 | 0.0158662 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0158537 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.28851 |
| PTMA | prothymosin, alpha | -0.255219 |
| RPS6 | ribosomal protein S6 | -0.102009 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0795709 |
| RPS8 | ribosomal protein S8 | -0.0761675 |
| RPL35A | ribosomal protein L35a | -0.0707951 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0538956 |
| RPL31 | ribosomal protein L31 | -0.053252 |
| RPL34 | ribosomal protein L34 | -0.0527265 |
| BMP10 | bone morphogenetic protein 10 | -0.0522952 |
| RPLP1 | ribosomal protein, large, P1 | -0.0498391 |
| FTL | ferritin, light polypeptide | -0.0461693 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0453659 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0449221 |
| ACTG1 | actin gamma 1 | -0.0448375 |
| PKM | pyruvate kinase, muscle | -0.0442431 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0434435 |
| RPL19 | ribosomal protein L19 | -0.0429969 |
| RPL32 | ribosomal protein L32 | -0.0402136 |
| RPL7A | ribosomal protein L7a | -0.039525 |
| RPS23 | ribosomal protein S23 | -0.0372621 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0354703 |
| MT2A | metallothionein 2A | -0.0354429 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0350609 |
| RPL26 | ribosomal protein L26 | -0.0345932 |
| AHNAK | AHNAK nucleoprotein | -0.0345324 |
| TMSB10 | thymosin beta 10 | -0.0342364 |
| S100A10 | S100 calcium binding protein A10 | -0.0332932 |
| RPS19 | ribosomal protein S19 | -0.0330266 |
| RPL23 | ribosomal protein L23 | -0.0318331 |
| RPS27A | ribosomal protein S27a | -0.0313746 |
| RPLP2 | ribosomal protein, large, P2 | -0.0311868 |
| RPL5 | ribosomal protein L5 | -0.0311454 |
| RPS25 | ribosomal protein S25 | -0.0308714 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0306315 |
| RPLP0 | ribosomal protein, large, P0 | -0.0305881 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0303823 |
| S100A4 | S100 calcium binding protein A4 | -0.0300143 |
| RPS13 | ribosomal protein S13 | -0.0294259 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0284676 |
| RPS24 | ribosomal protein S24 | -0.0281962 |
| RPL12 | ribosomal protein L12 | -0.0281917 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0278083 |
| S100A9 | S100 calcium binding protein A9 | -0.0277618 |
| RPS16 | ribosomal protein S16 | -0.0277303 |
| RPS3 | ribosomal protein S3 | -0.0274994 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0274489 |
| RPS11 | ribosomal protein S11 | -0.027218 |
| RPL36 | ribosomal protein L36 | -0.0267248 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0264199 |
| RPL37A | ribosomal protein L37a | -0.0260218 |
| CANX | calnexin | -0.0250053 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0246926 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0244536 |
| RPL8 | ribosomal protein L8 | -0.0242721 |
| RPS21 | ribosomal protein S21 | -0.0237687 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0237014 |
| HMGA1 | high mobility group AT-hook 1 | -0.0227498 |
| GNAS | GNAS complex locus | -0.0226879 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0224443 |
| RPS10 | ribosomal protein S10 | -0.0220387 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0217557 |
| RPL7 | ribosomal protein L7 | -0.0216909 |
| RPL9 | ribosomal protein L9 | -0.0216255 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.021446 |
| RPL35 | ribosomal protein L35 | -0.0212977 |
| CCNI | cyclin I | -0.0211591 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0209904 |
| DUSP6 | dual specificity phosphatase 6 | -0.020655 |
| PFN1 | profilin 1 | -0.0204117 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0202808 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0200965 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0199469 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0196417 |
| S100A6 | S100 calcium binding protein A6 | -0.0194177 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0194039 |
| TPI1 | triosephosphate isomerase 1 | -0.0190825 |
| CCND1 | cyclin D1 | -0.0189555 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0188895 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0187971 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0186839 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0185043 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0184364 |
| VIM | vimentin | -0.0183808 |
| RPL38 | ribosomal protein L38 | -0.0183364 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0181099 |
| RPS17 | ribosomal protein S17 | -0.0179051 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.017753 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0175396 |
| RPS5 | ribosomal protein S5 | -0.0174975 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.017435 |
| RPS14 | ribosomal protein S14 | -0.0172888 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0170546 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0170031 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.01695 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0168613 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0167847 |
| CREBBP | CREB binding protein | -0.0166808 |
| RPS29 | ribosomal protein S29 | -0.0166128 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0163968 |
