| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.120416 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.120026 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.119258 |
| RACK1 | receptor for activated C kinase 1 | 0.106956 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0893529 |
| VEGFA | vascular endothelial growth factor A | 0.0762919 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0754134 |
| NDRG1 | N-myc downstream regulated 1 | 0.0742593 |
| RPS4X | ribosomal protein S4, X-linked | 0.0712698 |
| VIM | vimentin | 0.0679058 |
| B2M | beta-2-microglobulin | 0.0625353 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0570703 |
| RPL23 | ribosomal protein L23 | 0.0556657 |
| FLNA | filamin A, alpha | 0.0551778 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0542592 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0498473 |
| YBX1 | Y box binding protein 1 | 0.048527 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0481231 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0444664 |
| CALR | calreticulin | 0.043368 |
| GOLGA4 | golgin A4 | 0.0433629 |
| RPS12 | ribosomal protein S12 | 0.042617 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0416031 |
| NAV2 | neuron navigator 2 | 0.0414867 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0411337 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0400686 |
| MKI67 | marker of proliferation Ki-67 | 0.0400658 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0395581 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0380019 |
| RPS8 | ribosomal protein S8 | 0.0373649 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0371726 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0366859 |
| CENPF | centromere protein F, 350/400kDa | 0.0366097 |
| OPTN | optineurin | 0.0356444 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0347314 |
| STAG2 | stromal antigen 2 | 0.0340301 |
| VCAN | versican | 0.034013 |
| ARRDC3 | arrestin domain containing 3 | 0.0340082 |
| TPM3 | tropomyosin 3 | 0.0338483 |
| RPS3 | ribosomal protein S3 | 0.033797 |
| RPL3 | ribosomal protein L3 | 0.0336856 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0336825 |
| STC2 | stanniocalcin 2 | 0.0326935 |
| RPL11 | ribosomal protein L11 | 0.0325746 |
| STC1 | stanniocalcin 1 | 0.0318873 |
| HLA-A | major histocompatibility complex, class I, A | 0.0317475 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0316692 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0314854 |
| PDE10A | phosphodiesterase 10A | 0.0314691 |
| CEP250 | centrosomal protein 250kDa | 0.0308393 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.030783 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0307448 |
| SMYD3 | SET and MYND domain containing 3 | 0.0301053 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0300016 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0299995 |
| MSN | moesin | 0.0294402 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0289423 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0288446 |
| RPS6 | ribosomal protein S6 | 0.0285915 |
| RPL26 | ribosomal protein L26 | 0.0285198 |
| ANLN | anillin, actin binding protein | 0.0282825 |
| PTMA | prothymosin, alpha | 0.028232 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0275239 |
| RPL5 | ribosomal protein L5 | 0.0267149 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.026651 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0266247 |
| DSTN | destrin (actin depolymerizing factor) | 0.0265813 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0265543 |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 | 0.0263673 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0262677 |
| MKRN1 | makorin ring finger protein 1 | 0.026192 |
| RPL37A | ribosomal protein L37a | 0.0260367 |
| RPL12 | ribosomal protein L12 | 0.0259792 |
| DSPP | dentin sialophosphoprotein | 0.025935 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0253428 |
| RPS2 | ribosomal protein S2 | 0.0251576 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0247489 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0246832 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0242859 |
| CD109 | CD109 molecule | 0.0242765 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0240996 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0240973 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0239821 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0239078 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0238768 |
| MATR3 | matrin 3 | 0.023627 |
| NONO | non-POU domain containing, octamer-binding | 0.0233236 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0230358 |
| YBX3 | Y box binding protein 3 | 0.0230089 |
| DIAPH3 | diaphanous-related formin 3 | 0.0229046 |
| KIF4A | kinesin family member 4A | 0.0228585 |
| SET | SET nuclear proto-oncogene | 0.0227107 |
| HLA-B | major histocompatibility complex, class I, B | 0.0225017 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0221803 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0217035 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0216604 |
| PCBP2 | poly(rC) binding protein 2 | 0.0216458 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0215797 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0215372 |
| CANX | calnexin | 0.0213941 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.123969 |
| BICC1 | BicC family RNA binding protein 1 | -0.105722 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0974874 |
| IER3 | immediate early response 3 | -0.071943 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0660708 |
| VCL | vinculin | -0.0599859 |
| RTN4 | reticulon 4 | -0.059523 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0494782 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0455881 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0445916 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0423041 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0388906 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0381238 |
| NABP1 | nucleic acid binding protein 1 | -0.0380973 |
| FOXO3 | forkhead box O3 | -0.0344428 |
| JMJD1C | jumonji domain containing 1C | -0.0322008 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.031942 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0315462 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0302358 |
| ANXA2 | annexin A2 | -0.0299604 |
| AHNAK | AHNAK nucleoprotein | -0.0297255 |
| RIGI | RNA sensor RIG-I | -0.0295795 |
| CD44 | CD44 molecule (Indian blood group) | -0.0290173 |
| KLF6 | Kruppel-like factor 6 | -0.0268221 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0268101 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0260558 |
| KYNU | kynureninase | -0.0259266 |
| SDC4 | syndecan 4 | -0.0258353 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0255319 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0254645 |
| THBS1 | thrombospondin 1 | -0.0252728 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0249517 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0242687 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0237525 |
| EXOC4 | exocyst complex component 4 | -0.0237269 |
| CLIC4 | chloride intracellular channel 4 | -0.0233846 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0233086 |
| OSMR | oncostatin M receptor | -0.0224543 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0224436 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0221746 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0219106 |
| EGFR | epidermal growth factor receptor | -0.0218996 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0218957 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0217202 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0214826 |
| RPS24 | ribosomal protein S24 | -0.0214807 |
| IL6ST | interleukin 6 signal transducer | -0.0214735 |
| ARF4 | ADP-ribosylation factor 4 | -0.0213618 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0213374 |
| KLHL5 | kelch-like family member 5 | -0.0209998 |
| TMSB10 | thymosin beta 10 | -0.0209383 |
| WDR1 | WD repeat domain 1 | -0.0206222 |
| BNC2 | basonuclin 2 | -0.0199741 |
| PHF21A | PHD finger protein 21A | -0.0198439 |
| ZNF292 | zinc finger protein 292 | -0.0197281 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0196905 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0194865 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0194662 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0194205 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0193397 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0190411 |
| NCOA7 | nuclear receptor coactivator 7 | -0.018934 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0186586 |
| DIAPH2 | diaphanous-related formin 2 | -0.0185303 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.018431 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0184214 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0183939 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0183883 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0182626 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0182102 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0181996 |
| KLF12 | Kruppel-like factor 12 | -0.0180104 |
| ZNF608 | zinc finger protein 608 | -0.017959 |
| QKI | QKI, KH domain containing, RNA binding | -0.0178658 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0178253 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0176172 |
| SQSTM1 | sequestosome 1 | -0.0175787 |
| CD2AP | CD2-associated protein | -0.0173984 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0171217 |
| TMEM132D | transmembrane protein 132D | -0.016601 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0164449 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0163657 |
| MED13 | mediator complex subunit 13 | -0.0161185 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0160905 |
| MAP1B | microtubule-associated protein 1B | -0.0160707 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0158721 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0158164 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0156894 |
| RPL6 | ribosomal protein L6 | -0.0156702 |
| DENND5A | DENN/MADD domain containing 5A | -0.0152919 |
| ARF1 | ADP-ribosylation factor 1 | -0.0151786 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0150555 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0149927 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0148875 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0148453 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0147694 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0146897 |
| FTL | ferritin, light polypeptide | -0.014687 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0146486 |
| PGK1 | phosphoglycerate kinase 1 | -0.0146382 |
