| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Levobupivacaine (hydrochloride)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.122963 |
| COL1A2 | collagen, type I, alpha 2 | 0.0681649 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0624726 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0597105 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0575849 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0575345 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.05708 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0559187 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0549027 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0538909 |
| WTAP | Wilms tumor 1 associated protein | 0.0484044 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0482737 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0469193 |
| NDRG1 | N-myc downstream regulated 1 | 0.0456798 |
| ATP13A3 | ATPase type 13A3 | 0.045416 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0453226 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0451309 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0445905 |
| FLNB | filamin B, beta | 0.0444596 |
| TXNRD1 | thioredoxin reductase 1 | 0.0435724 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.043411 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0414229 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0413356 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0410346 |
| RIOK3 | RIO kinase 3 | 0.0405918 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0404911 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0393849 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0384751 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0381797 |
| ARRDC3 | arrestin domain containing 3 | 0.0375651 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0365915 |
| NIBAN2 | niban apoptosis regulator 2 | 0.036449 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0357202 |
| FAM13A | family with sequence similarity 13, member A | 0.0357052 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0356909 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0350459 |
| IRF1 | interferon regulatory factor 1 | 0.0350346 |
| FNBP4 | formin binding protein 4 | 0.0349946 |
| TNRC6A | trinucleotide repeat containing 6A | 0.034833 |
| FNBP1L | formin binding protein 1-like | 0.0348193 |
| QKI | QKI, KH domain containing, RNA binding | 0.0343228 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0341995 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0335634 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0330151 |
| COPA | coatomer protein complex, subunit alpha | 0.0329933 |
| ACTN4 | actinin, alpha 4 | 0.0327736 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0317538 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0316869 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0314898 |
| ITGA6 | integrin, alpha 6 | 0.0312364 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.031117 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0311085 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0306041 |
| COL5A2 | collagen, type V, alpha 2 | 0.0299828 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0295818 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0293347 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0292986 |
| YBX3 | Y box binding protein 3 | 0.0292796 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0291221 |
| DENND4A | DENN/MADD domain containing 4A | 0.0289788 |
| RNF145 | ring finger protein 145 | 0.0289016 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0287398 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.028119 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0279296 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0278726 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.027742 |
| ETV6 | ets variant 6 | 0.0276954 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0274892 |
| TPI1 | triosephosphate isomerase 1 | 0.0273512 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0273078 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0271439 |
| GPHN | gephyrin | 0.0270368 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0270098 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0269292 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0267854 |
| ANXA1 | annexin A1 | 0.026743 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0267182 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0265189 |
| PARD3 | par-3 family cell polarity regulator | 0.0264583 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.0260784 |
| LAMB3 | laminin, beta 3 | 0.02605 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0259445 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0255083 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0254875 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0253964 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.025244 |
| RLF | rearranged L-myc fusion | 0.0250804 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.024802 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0247501 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0246318 |
| ORC4 | origin recognition complex, subunit 4 | 0.0244992 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0242864 |
| CDK17 | cyclin-dependent kinase 17 | 0.0242846 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0242444 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0239103 |
| ANXA2 | annexin A2 | 0.0237682 |
| HELZ | helicase with zinc finger | 0.0237533 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0237451 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0237378 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.0237221 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.267758 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.156636 |
| MT2A | metallothionein 2A | -0.152037 |
| HLA-B | major histocompatibility complex, class I, B | -0.143771 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.117387 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0978534 |
| VIM | vimentin | -0.095809 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0953726 |
| VCL | vinculin | -0.0730969 |
| LOX | lysyl oxidase | -0.0722413 |
| SDC4 | syndecan 4 | -0.0653328 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0633712 |
| CALD1 | caldesmon 1 | -0.0609651 |
| MAP1B | microtubule-associated protein 1B | -0.0588974 |
| GNAS | GNAS complex locus | -0.0578239 |
| CANX | calnexin | -0.0555122 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0549692 |
| RAD51B | RAD51 paralog B | -0.0535909 |
| SEC24D | SEC24 family member D | -0.0535291 |
| PRELID2 | PRELI domain containing 2 | -0.0530987 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0528853 |
| TMSB10 | thymosin beta 10 | -0.0508726 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0504339 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0498723 |
| CD44 | CD44 molecule (Indian blood group) | -0.0488625 |
| SMYD3 | SET and MYND domain containing 3 | -0.0480136 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0479881 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0478097 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0453788 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0443441 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0439202 |
| NRXN3 | neurexin 3 | -0.042545 |
| ACTG1 | actin gamma 1 | -0.0423689 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0413332 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0413179 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0410068 |
| RPL11 | ribosomal protein L11 | -0.0401044 |
| HIP1 | huntingtin interacting protein 1 | -0.0392256 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0389085 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0388518 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0388352 |
| PRSS23 | protease, serine, 23 | -0.038813 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0384561 |
| ZNF395 | zinc finger protein 395 | -0.0371068 |
| RSF1 | remodeling and spacing factor 1 | -0.0360286 |
| GLG1 | golgi glycoprotein 1 | -0.035927 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | -0.035383 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0353644 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0353282 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0349376 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0340793 |
| HLA-C | major histocompatibility complex, class I, C | -0.0335267 |
| AHNAK | AHNAK nucleoprotein | -0.0335023 |
| RUNX1 | runt-related transcription factor 1 | -0.0332549 |
| NKTR | natural killer cell triggering receptor | -0.0332047 |
| CALU | calumenin | -0.0330747 |
| RAI14 | retinoic acid induced 14 | -0.0329358 |
| PTGES2 | prostaglandin E synthase 2 | -0.0327206 |
| FRMD6 | FERM domain containing 6 | -0.0326991 |
| ANLN | anillin, actin binding protein | -0.0326102 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0324213 |
| MEF2A | myocyte enhancer factor 2A | -0.0322848 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.031927 |
| PTN | pleiotrophin | -0.0314252 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0314038 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0313909 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0312744 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0311931 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0310943 |
| MORF4L2 | mortality factor 4 like 2 | -0.0308805 |
| HMGA2 | high mobility group AT-hook 2 | -0.0307238 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | -0.0306249 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0302043 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0301564 |
| COG6 | component of oligomeric golgi complex 6 | -0.0300413 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0299435 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0294973 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0294923 |
| CDK13 | cyclin-dependent kinase 13 | -0.029202 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0290657 |
| CADM1 | cell adhesion molecule 1 | -0.0289612 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.028725 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0285375 |
| SLC25A51 | solute carrier family 25, member 51 | -0.0285107 |
| KAZN | kazrin, periplakin interacting protein | -0.0284422 |
| ENO1 | enolase 1, (alpha) | -0.0283859 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0281245 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0278917 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0278496 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0275147 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0273576 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.027336 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0273243 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | -0.027162 |
| GOLIM4 | golgi integral membrane protein 4 | -0.0271104 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0269832 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0268687 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0267786 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0265608 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0260846 |
