| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.0731067 |
| NAV2 | neuron navigator 2 | 0.0546216 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0519331 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0451672 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0436558 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0414551 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0375435 |
| NUP58 | nucleoporin 58 | 0.0366575 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0354186 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0347361 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0341566 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0334114 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0331511 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0324721 |
| MSN | moesin | 0.032194 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0320843 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.030333 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0296479 |
| FLNB | filamin B, beta | 0.0291761 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0286398 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0283996 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0276925 |
| CEP250 | centrosomal protein 250kDa | 0.0272257 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0270971 |
| RAD51B | RAD51 paralog B | 0.0270933 |
| PRELID2 | PRELI domain containing 2 | 0.0267589 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0267258 |
| DNER | delta/notch-like EGF repeat containing | 0.0264592 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0262742 |
| PYGL | phosphorylase, glycogen, liver | 0.0262279 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0256667 |
| ATXN1 | ataxin 1 | 0.0256075 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0254253 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0249094 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0245258 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0233319 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0226013 |
| NBAS | neuroblastoma amplified sequence | 0.0225837 |
| ATP13A3 | ATPase type 13A3 | 0.022454 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0222952 |
| OSMR | oncostatin M receptor | 0.0222145 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0220492 |
| CAPRIN2 | caprin family member 2 | 0.0220175 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.0218093 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0214205 |
| MYOF | myoferlin | 0.0213589 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0210363 |
| DST | dystonin | 0.0207421 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0205822 |
| SNX14 | sorting nexin 14 | 0.0202401 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0201065 |
| ZNF292 | zinc finger protein 292 | 0.0200827 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0197279 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0194199 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0194114 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0192524 |
| RACK1 | receptor for activated C kinase 1 | 0.0191709 |
| PRKCE | protein kinase C, epsilon | 0.0191695 |
| CUL4B | cullin 4B | 0.018985 |
| MCL1 | myeloid cell leukemia 1 | 0.0189075 |
| FMN1 | formin 1 | 0.0188351 |
| SNX13 | sorting nexin 13 | 0.0187784 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0184864 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0182089 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0182017 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0181293 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0181275 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0181203 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0179249 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0178839 |
| PRSS23 | protease, serine, 23 | 0.0176839 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.01761 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0175254 |
| NGLY1 | N-glycanase 1 | 0.0174823 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0172179 |
| SEPTIN2 | septin 2 | 0.0171507 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0170384 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 | 0.0169841 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0167892 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0167866 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0167793 |
| RANBP2 | RAN binding protein 2 | 0.0166552 |
| FOXJ3 | forkhead box J3 | 0.0166105 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0165249 |
| AURKA | aurora kinase A | 0.0163063 |
| TARDBP | TAR DNA binding protein | 0.0162723 |
| SEPTIN9 | septin 9 | 0.0162107 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0161432 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0160277 |
| TPM3 | tropomyosin 3 | 0.0156947 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0156581 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0156284 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0155311 |
| ARRDC3 | arrestin domain containing 3 | 0.0153886 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0153587 |
| VCL | vinculin | 0.0151593 |
| RNF145 | ring finger protein 145 | 0.0151145 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0150614 |
| ATM | ATM serine/threonine kinase | 0.0148778 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0148234 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.406006 |
| VIM | vimentin | -0.0981666 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0644997 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0552477 |
| GNAS | GNAS complex locus | -0.0479908 |
| RPLP1 | ribosomal protein, large, P1 | -0.0427794 |
| SQSTM1 | sequestosome 1 | -0.0415249 |
| GOLGA4 | golgin A4 | -0.040787 |
| RPS8 | ribosomal protein S8 | -0.0367286 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0361206 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0345982 |
| RPS13 | ribosomal protein S13 | -0.0328418 |
| RPL12 | ribosomal protein L12 | -0.0293759 |
| PTMA | prothymosin, alpha | -0.0276403 |
| TMSB10 | thymosin beta 10 | -0.0273775 |
| HMGA1 | high mobility group AT-hook 1 | -0.0266114 |
| RPLP0 | ribosomal protein, large, P0 | -0.0255663 |
| RPS23 | ribosomal protein S23 | -0.0254835 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0239129 |
| SETD5 | SET domain containing 5 | -0.0236544 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0234763 |
| RPS6 | ribosomal protein S6 | -0.0231077 |
| FTL | ferritin, light polypeptide | -0.0228666 |
| RPL32 | ribosomal protein L32 | -0.0222807 |
| RPLP2 | ribosomal protein, large, P2 | -0.0216141 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0210527 |
| EGR1 | early growth response 1 | -0.0207659 |
| ADIPOR2 | adiponectin receptor 2 | -0.0205085 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0202588 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.0199757 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0199193 |
| CCNI | cyclin I | -0.0198693 |
| RPS11 | ribosomal protein S11 | -0.0196704 |
| RPL30 | ribosomal protein L30 | -0.0195941 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0193524 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.019251 |
| SETX | senataxin | -0.0192345 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0191812 |
| RPS29 | ribosomal protein S29 | -0.0189541 |
| ANXA2 | annexin A2 | -0.0187332 |
| RPS19 | ribosomal protein S19 | -0.0186037 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0184281 |
| RPL35A | ribosomal protein L35a | -0.0184033 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0182847 |
| ANXA1 | annexin A1 | -0.0181984 |
| RPL36 | ribosomal protein L36 | -0.0179271 |
| RTN3 | reticulon 3 | -0.0177908 |
| TP53 | tumor protein p53 | -0.0175972 |
| RPL31 | ribosomal protein L31 | -0.0174624 |
| RPS16 | ribosomal protein S16 | -0.017271 |
| RPL35 | ribosomal protein L35 | -0.0167983 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0167821 |
| RPL4 | ribosomal protein L4 | -0.0165775 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0163267 |
| RPS14 | ribosomal protein S14 | -0.0162316 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0161773 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0160815 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0160428 |
| NPR2 | natriuretic peptide receptor 2 | -0.0159462 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0159241 |
| RPL11 | ribosomal protein L11 | -0.0158641 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0158151 |
| MORF4L2 | mortality factor 4 like 2 | -0.0157938 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0157316 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | -0.0157121 |
| NIN | ninein (GSK3B interacting protein) | -0.0155614 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0154923 |
| RASAL2 | RAS protein activator like 2 | -0.015414 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0152913 |
| TUBB4B | tubulin, beta 4B class IVb | -0.015287 |
| TMEM263 | transmembrane protein 263 | -0.0152846 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0151828 |
| RPL34 | ribosomal protein L34 | -0.0151674 |
| BSG | basigin (Ok blood group) | -0.0151551 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0151023 |
| ARF1 | ADP-ribosylation factor 1 | -0.0150987 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0148605 |
| HLA-C | major histocompatibility complex, class I, C | -0.0147117 |
| PFN1 | profilin 1 | -0.0147062 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0147001 |
| SEPTIN7 | septin 7 | -0.0146309 |
| CENPP | centromere protein P | -0.01453 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0143813 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0143462 |
| CCND1 | cyclin D1 | -0.0142532 |
| HMGB1 | high mobility group box 1 | -0.0140504 |
| RPS20 | ribosomal protein S20 | -0.0139888 |
| RPS3 | ribosomal protein S3 | -0.013682 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0136539 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | -0.013618 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0135796 |
| BLM | Bloom syndrome, RecQ helicase-like | -0.0135737 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0135575 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.0135126 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0133256 |
| RPS21 | ribosomal protein S21 | -0.0133223 |
| MED13 | mediator complex subunit 13 | -0.0133196 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0133164 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0131963 |
| TUBA1B | tubulin, alpha 1b | -0.0131088 |