| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RACK1 | receptor for activated C kinase 1 | 0.1861 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.081703 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.077339 |
| RPL26 | ribosomal protein L26 | 0.0722835 |
| RPS12 | ribosomal protein S12 | 0.0615958 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0584756 |
| FAT1 | FAT atypical cadherin 1 | 0.0569606 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0569503 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0518884 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0506147 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0498688 |
| TPM3 | tropomyosin 3 | 0.0495914 |
| HDGF | hepatoma-derived growth factor | 0.0484961 |
| NDRG1 | N-myc downstream regulated 1 | 0.044229 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0433317 |
| VEGFA | vascular endothelial growth factor A | 0.0413139 |
| CENPF | centromere protein F, 350/400kDa | 0.0391981 |
| FLNA | filamin A, alpha | 0.0390076 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0384131 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0383017 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.036446 |
| YBX1 | Y box binding protein 1 | 0.035572 |
| RPL37A | ribosomal protein L37a | 0.0349225 |
| SMAD3 | SMAD family member 3 | 0.0340967 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0334494 |
| DST | dystonin | 0.0331139 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0330956 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0310322 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0301982 |
| STC2 | stanniocalcin 2 | 0.0297512 |
| CALR | calreticulin | 0.0293444 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0290847 |
| RUNX1 | runt-related transcription factor 1 | 0.0289438 |
| RPL3 | ribosomal protein L3 | 0.028047 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0279684 |
| RPL11 | ribosomal protein L11 | 0.0279302 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0276658 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0276381 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0272596 |
| EFNA5 | ephrin-A5 | 0.0272092 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0267905 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0267461 |
| KIF5B | kinesin family member 5B | 0.026734 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0265019 |
| SBF2 | SET binding factor 2 | 0.0263689 |
| ETNK1 | ethanolamine kinase 1 | 0.0263517 |
| ANXA5 | annexin A5 | 0.0262207 |
| AFDN | afadin, adherens junction formation factor | 0.0259369 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0259313 |
| HMGB3 | high mobility group box 3 | 0.0259126 |
| RNF145 | ring finger protein 145 | 0.0258702 |
| SEPTIN9 | septin 9 | 0.0254104 |
| RPL37 | ribosomal protein L37 | 0.0254 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0252484 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0251775 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0246304 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0245337 |
| FMNL2 | formin-like 2 | 0.0237013 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0236094 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0235944 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0234517 |
| OPTN | optineurin | 0.0234061 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0233954 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0233555 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0233153 |
| CADM1 | cell adhesion molecule 1 | 0.0231442 |
| USP22 | ubiquitin specific peptidase 22 | 0.0230447 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0229948 |
| RPL30 | ribosomal protein L30 | 0.0229645 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0228632 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.022859 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0227391 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0226778 |
| XPO1 | exportin 1 | 0.0224736 |
| SNX13 | sorting nexin 13 | 0.0223938 |
| SET | SET nuclear proto-oncogene | 0.0221902 |
| MYO1B | myosin IB | 0.0218862 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.021843 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0217578 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0217406 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.02155 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0214441 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0213421 |
| NUP58 | nucleoporin 58 | 0.0210935 |
| GPATCH2L | G patch domain containing 2-like | 0.0210862 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0208109 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0206584 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0205512 |
| RPS27 | ribosomal protein S27 | 0.0205213 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0204955 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.0203817 |
| RHOA | ras homolog family member A | 0.0203484 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0201387 |
| PNN | pinin, desmosome associated protein | 0.0200933 |
| CTBP2 | C-terminal binding protein 2 | 0.0200557 |
| ZNF148 | zinc finger protein 148 | 0.0200553 |
| PCM1 | pericentriolar material 1 | 0.0200316 |
| TPR | translocated promoter region, nuclear basket protein | 0.0200089 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0199716 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0197176 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.480472 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.183872 |
| FN1 | fibronectin 1 | -0.0869912 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0801037 |
| FTL | ferritin, light polypeptide | -0.0729375 |
| ASPH | aspartate beta-hydroxylase | -0.0717251 |
| HLA-B | major histocompatibility complex, class I, B | -0.0681251 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0568397 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0504793 |
| TXNIP | thioredoxin interacting protein | -0.0497665 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0490877 |
| IER3 | immediate early response 3 | -0.0433064 |
| H1-0 | H1.0 linker histone | -0.0428005 |
| PTMA | prothymosin, alpha | -0.0396176 |
| SYT1 | synaptotagmin I | -0.0391787 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0385326 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0380316 |
| RPS24 | ribosomal protein S24 | -0.0357907 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0350635 |
| SQSTM1 | sequestosome 1 | -0.0319665 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.031316 |
| HMGA2 | high mobility group AT-hook 2 | -0.0309146 |
| AHNAK | AHNAK nucleoprotein | -0.0305422 |
| S100A10 | S100 calcium binding protein A10 | -0.0305225 |
| TMSB10 | thymosin beta 10 | -0.0305114 |
| EREG | epiregulin | -0.0302398 |
| ETV1 | ets variant 1 | -0.0295617 |
| YBX3 | Y box binding protein 3 | -0.0292472 |
| TGFA | transforming growth factor, alpha | -0.0289324 |
| EGR1 | early growth response 1 | -0.0288821 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0288469 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.026342 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0261753 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0259792 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0256538 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0254856 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0254676 |
| ITGA1 | integrin, alpha 1 | -0.0253816 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0251239 |
| THBS1 | thrombospondin 1 | -0.0245243 |
| CANX | calnexin | -0.0244577 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0243156 |
| RPL28 | ribosomal protein L28 | -0.0242331 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0242257 |
| TMEM263 | transmembrane protein 263 | -0.023899 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0237656 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0237651 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0237608 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0231425 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0230057 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0229164 |
| APP | amyloid beta (A4) precursor protein | -0.02285 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0228302 |
| NTN4 | netrin 4 | -0.0228037 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0225295 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0224346 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0222235 |
| ACTG1 | actin gamma 1 | -0.0218744 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0218605 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0218032 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0217892 |
| INTS6 | integrator complex subunit 6 | -0.0217675 |
| VCAN | versican | -0.0216813 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0215435 |
| HBP1 | HMG-box transcription factor 1 | -0.0213935 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0211625 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0209231 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0208311 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0208057 |
| RHEB | Ras homolog enriched in brain | -0.0205174 |
| LDHA | lactate dehydrogenase A | -0.0204399 |
| MORF4L2 | mortality factor 4 like 2 | -0.0202958 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0199704 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0198534 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0196358 |
| MAP1B | microtubule-associated protein 1B | -0.0196153 |
| SETD5 | SET domain containing 5 | -0.019561 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0192249 |
| RPS16 | ribosomal protein S16 | -0.0191885 |
| EVI5 | ecotropic viral integration site 5 | -0.019149 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0190201 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0190029 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0189418 |
| UBAP1 | ubiquitin associated protein 1 | -0.0188261 |
| FNDC3B | fibronectin type III domain containing 3B | -0.018721 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0186461 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0186435 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0185339 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0185059 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0184336 |
| ZNF609 | zinc finger protein 609 | -0.0184252 |
| RPS27A | ribosomal protein S27a | -0.0184177 |
| SEC24D | SEC24 family member D | -0.0183859 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0183821 |
| IL6ST | interleukin 6 signal transducer | -0.018382 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.018309 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | -0.0182569 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0180914 |
| RUNX2 | runt-related transcription factor 2 | -0.0179897 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0179329 |
