| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0740314 |
| DSPP | dentin sialophosphoprotein | 0.0639405 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.061746 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0608591 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0541414 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0534899 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0473775 |
| TMF1 | TATA element modulatory factor 1 | 0.0459184 |
| FLNA | filamin A, alpha | 0.0396135 |
| PLEC | plectin | 0.0388179 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0384861 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0376984 |
| SRP54 | signal recognition particle 54kDa | 0.0349349 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0339551 |
| RACK1 | receptor for activated C kinase 1 | 0.0331822 |
| SET | SET nuclear proto-oncogene | 0.03201 |
| TPM3 | tropomyosin 3 | 0.0316568 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0311814 |
| RPL26 | ribosomal protein L26 | 0.0308786 |
| KIF5B | kinesin family member 5B | 0.0306366 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0306067 |
| RPL3 | ribosomal protein L3 | 0.0302285 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0297877 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0297419 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0295917 |
| LMO7 | LIM domain 7 | 0.0284719 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0275916 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0272543 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0271907 |
| GOLGA4 | golgin A4 | 0.0269959 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0269029 |
| RPL23 | ribosomal protein L23 | 0.0262627 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0258147 |
| HDLBP | high density lipoprotein binding protein | 0.0255266 |
| SRPK2 | SRSF protein kinase 2 | 0.0252905 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0250203 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.024989 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0247998 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0247831 |
| SPAG9 | sperm associated antigen 9 | 0.0247406 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0243941 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0242695 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0238808 |
| CALR | calreticulin | 0.0237114 |
| MATR3 | matrin 3 | 0.023229 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0231573 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0229744 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0229274 |
| TOP1 | topoisomerase (DNA) I | 0.0229013 |
| HMGB2 | high mobility group box 2 | 0.0226404 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0225841 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0224702 |
| HOXB3 | homeobox B3 | 0.0223071 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0222493 |
| CTBP2 | C-terminal binding protein 2 | 0.0220667 |
| PCBP3 | poly(rC) binding protein 3 | 0.0217534 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0217101 |
| RCOR1 | REST corepressor 1 | 0.0214663 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0214132 |
| NCKAP1 | NCK-associated protein 1 | 0.0213526 |
| KIAA1671 | KIAA1671 | 0.0213291 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0212209 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0210163 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0209941 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0209475 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0208784 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.020837 |
| MEF2A | myocyte enhancer factor 2A | 0.0206941 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0206035 |
| PCBP2 | poly(rC) binding protein 2 | 0.0205402 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0204973 |
| HM13 | histocompatibility (minor) 13 | 0.0203143 |
| UNC13A | unc-13 homolog A (C. elegans) | 0.0202461 |
| FAM168B | family with sequence similarity 168, member B | 0.0200301 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0200058 |
| RPL13A | ribosomal protein L13a | 0.0198252 |
| RAB18 | RAB18, member RAS oncogene family | 0.0197203 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0194749 |
| AFDN | afadin, adherens junction formation factor | 0.0194712 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0193755 |
| SLK | STE20-like kinase | 0.0191688 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0191427 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0191295 |
| HYOU1 | hypoxia up-regulated 1 | 0.0191264 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0190923 |
| VGLL4 | vestigial-like family member 4 | 0.0187919 |
| VEGFA | vascular endothelial growth factor A | 0.0186987 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0185845 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0185437 |
| SCFD1 | sec1 family domain containing 1 | 0.0184701 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0184546 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.018379 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0183279 |
| MYO6 | myosin VI | 0.0183258 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0183177 |
| MRTFA | myocardin related transcription factor A | 0.0182848 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.0182704 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.018229 |
| PDZD8 | PDZ domain containing 8 | 0.0181937 |
| RPL7A | ribosomal protein L7a | 0.0181849 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0974009 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0920522 |
| FTL | ferritin, light polypeptide | -0.0728621 |
| EGR1 | early growth response 1 | -0.0566353 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0534898 |
| ANXA2 | annexin A2 | -0.0507352 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0459737 |
| MYOF | myoferlin | -0.0448555 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0427562 |
| EHBP1 | EH domain binding protein 1 | -0.0419885 |
| TMSB10 | thymosin beta 10 | -0.0412686 |
| SNX9 | sorting nexin 9 | -0.0403791 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0400463 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0399014 |
| EZR | ezrin | -0.0384897 |
| SERINC5 | serine incorporator 5 | -0.0375232 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0365155 |
| H1-0 | H1.0 linker histone | -0.0361202 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0350275 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0335678 |
| PKP4 | plakophilin 4 | -0.0333211 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0328781 |
| EXOC4 | exocyst complex component 4 | -0.031877 |
| ECT2 | epithelial cell transforming 2 | -0.031002 |
| TMEM123 | transmembrane protein 123 | -0.0307278 |
| PRELID2 | PRELI domain containing 2 | -0.0307012 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0300857 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0300229 |
| FAM3C | family with sequence similarity 3, member C | -0.0292647 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0291253 |
| IER3 | immediate early response 3 | -0.0288602 |
| CD2AP | CD2-associated protein | -0.0286905 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0284448 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0281089 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0280309 |
| SMYD3 | SET and MYND domain containing 3 | -0.026803 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0266916 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0263889 |
| WWOX | WW domain containing oxidoreductase | -0.0263532 |
| FOSL1 | FOS-like antigen 1 | -0.0262309 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0260841 |
| LDHA | lactate dehydrogenase A | -0.0258063 |
| NHSL1 | NHS-like 1 | -0.0256199 |
| RTN4 | reticulon 4 | -0.0255511 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0253685 |
| RUNX1 | runt-related transcription factor 1 | -0.0253396 |
| JMJD1C | jumonji domain containing 1C | -0.0252454 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0252054 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.024746 |
| FRMD5 | FERM domain containing 5 | -0.0246718 |
| S100A10 | S100 calcium binding protein A10 | -0.0241059 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0236651 |
| PTMA | prothymosin, alpha | -0.023453 |
| TRIM56 | tripartite motif containing 56 | -0.0231528 |
| FHIT | fragile histidine triad | -0.0230501 |
| PLSCR1 | phospholipid scramblase 1 | -0.0227001 |
| DIAPH2 | diaphanous-related formin 2 | -0.0223292 |
| CDCP1 | CUB domain containing protein 1 | -0.0221592 |
| RNF213 | ring finger protein 213 | -0.0221387 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0220558 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0217821 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0215511 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0214241 |
| RPL8 | ribosomal protein L8 | -0.0213669 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0213248 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0208735 |
| AZIN1 | antizyme inhibitor 1 | -0.0207275 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0206489 |
| FAT1 | FAT atypical cadherin 1 | -0.0205807 |
| RPS11 | ribosomal protein S11 | -0.0205695 |
| CCND1 | cyclin D1 | -0.0205412 |
| TXNIP | thioredoxin interacting protein | -0.020237 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0202019 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0201035 |
| TPX2 | TPX2, microtubule-associated | -0.0197782 |
| S100A11 | S100 calcium binding protein A11 | -0.0195805 |
| CLDN4 | claudin 4 | -0.0192232 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0191271 |
| SQSTM1 | sequestosome 1 | -0.0190485 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0189434 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0186083 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0184843 |
| FNIP1 | folliculin interacting protein 1 | -0.0183445 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0181558 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0180616 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0179808 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0178621 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0177752 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0177289 |
| CUX1 | cut-like homeobox 1 | -0.0177207 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.01769 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0176603 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0175475 |
| HDAC9 | histone deacetylase 9 | -0.0175043 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0173442 |
| GPSM2 | G-protein signaling modulator 2 | -0.0173041 |
| EDN1 | endothelin 1 | -0.0170756 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0170733 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0168882 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0167171 |
