| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.137142 |
| MKI67 | marker of proliferation Ki-67 | 0.0778706 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0755832 |
| RACK1 | receptor for activated C kinase 1 | 0.0684372 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0683802 |
| DSPP | dentin sialophosphoprotein | 0.066364 |
| PGK1 | phosphoglycerate kinase 1 | 0.0619146 |
| PROX1 | prospero homeobox 1 | 0.0585698 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0560612 |
| DST | dystonin | 0.0542709 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0531631 |
| RBM39 | RNA binding motif protein 39 | 0.0511164 |
| LMO7 | LIM domain 7 | 0.049406 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0441448 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0427824 |
| ANLN | anillin, actin binding protein | 0.040343 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0393885 |
| DIAPH3 | diaphanous-related formin 3 | 0.0391869 |
| OGA | O-GlcNAcase | 0.0383566 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0380482 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0374815 |
| AOPEP | aminopeptidase O (putative) | 0.0342258 |
| ZNF292 | zinc finger protein 292 | 0.03422 |
| STAG2 | stromal antigen 2 | 0.0340468 |
| TMF1 | TATA element modulatory factor 1 | 0.0337487 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.033237 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0317188 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0314465 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0314034 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0312581 |
| ENO1 | enolase 1, (alpha) | 0.0312579 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.0307337 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0306871 |
| KIZ | kizuna centrosomal protein | 0.0305447 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0301985 |
| PLEC | plectin | 0.0301545 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0295834 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0291825 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0291488 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0290611 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0286762 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0286736 |
| HMGB2 | high mobility group box 2 | 0.0283665 |
| AHNAK | AHNAK nucleoprotein | 0.0281311 |
| EFNB2 | ephrin-B2 | 0.0275922 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0274328 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0270673 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0269889 |
| AFDN | afadin, adherens junction formation factor | 0.026378 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0260123 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0258265 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0256434 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0256026 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0255956 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0254682 |
| UTRN | utrophin | 0.0253146 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0250932 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0249682 |
| ABHD2 | abhydrolase domain containing 2 | 0.0248386 |
| MORF4L2 | mortality factor 4 like 2 | 0.0246145 |
| TMSB4X | thymosin beta 4, X-linked | 0.0244953 |
| CCDC82 | coiled-coil domain containing 82 | 0.0241171 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0240955 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0239965 |
| FOXP1 | forkhead box P1 | 0.0237917 |
| ITGA6 | integrin, alpha 6 | 0.0237134 |
| KRT8 | keratin 8, type II | 0.0232706 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0229765 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0229136 |
| TMEM123 | transmembrane protein 123 | 0.0229001 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0227512 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0226948 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.0226723 |
| H1-0 | H1.0 linker histone | 0.0226695 |
| LDHA | lactate dehydrogenase A | 0.022654 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | 0.0226192 |
| HDLBP | high density lipoprotein binding protein | 0.022493 |
| PRELID2 | PRELI domain containing 2 | 0.0224773 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0224338 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0223189 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0222609 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0221266 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0218976 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.021833 |
| CENPF | centromere protein F, 350/400kDa | 0.0215314 |
| RPS4X | ribosomal protein S4, X-linked | 0.0213533 |
| MALT1 | MALT1 paracaspase | 0.0212667 |
| VGLL4 | vestigial-like family member 4 | 0.0210954 |
| SERINC1 | serine incorporator 1 | 0.0210905 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0210615 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0210464 |
| EMP1 | epithelial membrane protein 1 | 0.0207376 |
| PHF3 | PHD finger protein 3 | 0.0207252 |
| FLNA | filamin A, alpha | 0.0206783 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0206525 |
| CANX | calnexin | 0.0206506 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0206088 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0205693 |
| FANCI | Fanconi anemia, complementation group I | 0.0205114 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0204532 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.13211 |
| RPS6 | ribosomal protein S6 | -0.127374 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.110805 |
| TMSB10 | thymosin beta 10 | -0.095027 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0852801 |
| RPL35A | ribosomal protein L35a | -0.0685256 |
| CCND1 | cyclin D1 | -0.0655964 |
| CDH13 | cadherin 13 | -0.0582861 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0574445 |
| RPS19 | ribosomal protein S19 | -0.0568044 |
| FTL | ferritin, light polypeptide | -0.0558643 |
| POTEF | POTE ankyrin domain family, member F | -0.0532299 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0493986 |
| HMGA1 | high mobility group AT-hook 1 | -0.049323 |
| VCL | vinculin | -0.0492449 |
| PFN1 | profilin 1 | -0.0457329 |
| INTS6 | integrator complex subunit 6 | -0.0451999 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0451013 |
| MT2A | metallothionein 2A | -0.0442964 |
| RPL23 | ribosomal protein L23 | -0.0434907 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0424057 |
| RPS23 | ribosomal protein S23 | -0.0414179 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | -0.0410455 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0410184 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0398239 |
| RPLP2 | ribosomal protein, large, P2 | -0.0397743 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0387644 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0386859 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0380666 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0371446 |
| MYO1D | myosin ID | -0.0366767 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0361648 |
| ASPH | aspartate beta-hydroxylase | -0.0361405 |
| RPL28 | ribosomal protein L28 | -0.0355724 |
| EGR1 | early growth response 1 | -0.035348 |
| FLNB | filamin B, beta | -0.0345284 |
| RBP1 | retinol binding protein 1, cellular | -0.0335094 |
| RPS13 | ribosomal protein S13 | -0.0333101 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0332818 |
| RPL31 | ribosomal protein L31 | -0.0315409 |
| RPS21 | ribosomal protein S21 | -0.0311783 |
| FRMD5 | FERM domain containing 5 | -0.0309075 |
| BCL2L1 | BCL2-like 1 | -0.0308932 |
| RPS11 | ribosomal protein S11 | -0.030753 |
| PKM | pyruvate kinase, muscle | -0.0305799 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0302235 |
| RPS8 | ribosomal protein S8 | -0.0300474 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0296618 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0295704 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0295485 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.029542 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0295148 |
| SRPK2 | SRSF protein kinase 2 | -0.0293901 |
| RPS25 | ribosomal protein S25 | -0.0293594 |
| PCBP2 | poly(rC) binding protein 2 | -0.0292519 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0292236 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0291689 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0287329 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.028385 |
| RPS14 | ribosomal protein S14 | -0.0280533 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0279505 |
| UBAP2 | ubiquitin associated protein 2 | -0.027927 |
| RPS17 | ribosomal protein S17 | -0.02749 |
| RPS29 | ribosomal protein S29 | -0.0272135 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0268686 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0267937 |
| RPL21 | ribosomal protein L21 | -0.0267756 |
| S100A9 | S100 calcium binding protein A9 | -0.0264484 |
| WDR43 | WD repeat domain 43 | -0.0263183 |
| RPS10 | ribosomal protein S10 | -0.0261564 |
| RPS24 | ribosomal protein S24 | -0.0255497 |
| CD44 | CD44 molecule (Indian blood group) | -0.0254335 |
| RPS15 | ribosomal protein S15 | -0.0251578 |
| WWOX | WW domain containing oxidoreductase | -0.0251245 |
| RAD51B | RAD51 paralog B | -0.0249978 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0247507 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0246715 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0245105 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0241099 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0236548 |
| ASTN2 | astrotactin 2 | -0.0236271 |
| TGM2 | transglutaminase 2 | -0.0235359 |
| CCNL1 | cyclin L1 | -0.0234899 |
| NOP56 | NOP56 ribonucleoprotein | -0.023408 |
| CUX1 | cut-like homeobox 1 | -0.023339 |
| RPL36A | ribosomal protein L36a | -0.0233068 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.023224 |
| ACTN4 | actinin, alpha 4 | -0.0232154 |
| RCOR1 | REST corepressor 1 | -0.0231092 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0230579 |
| RPS5 | ribosomal protein S5 | -0.0229769 |
| FHIT | fragile histidine triad | -0.0225348 |
| ACTN1 | actinin, alpha 1 | -0.0222843 |
| PTMS | parathymosin | -0.022257 |
| EGFR | epidermal growth factor receptor | -0.0220844 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0218446 |
| HSPE1 | heat shock 10kDa protein 1 | -0.0215917 |
| COBL | cordon-bleu WH2 repeat protein | -0.0215517 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.02152 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0211035 |
