| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Levobupivacaine (hydrochloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.137978 |
| FN1 | fibronectin 1 | 0.114184 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.105318 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0919825 |
| NDRG1 | N-myc downstream regulated 1 | 0.088171 |
| RACK1 | receptor for activated C kinase 1 | 0.0803649 |
| COL6A1 | collagen, type VI, alpha 1 | 0.062868 |
| CALR | calreticulin | 0.0595261 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.059333 |
| RPS12 | ribosomal protein S12 | 0.0571631 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0553179 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0547565 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0538697 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0537451 |
| GOLGA4 | golgin A4 | 0.0523268 |
| VIM | vimentin | 0.0521354 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0493389 |
| DST | dystonin | 0.0490886 |
| ADM | adrenomedullin | 0.0480406 |
| ENO1 | enolase 1, (alpha) | 0.0468982 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0465261 |
| FTL | ferritin, light polypeptide | 0.0437211 |
| RPL23 | ribosomal protein L23 | 0.0432879 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0425867 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0417163 |
| STC2 | stanniocalcin 2 | 0.0393308 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0390236 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0387759 |
| MT2A | metallothionein 2A | 0.037757 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0373938 |
| YBX1 | Y box binding protein 1 | 0.0371398 |
| VEGFA | vascular endothelial growth factor A | 0.036477 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0356692 |
| TPM3 | tropomyosin 3 | 0.0355466 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0354287 |
| RPL11 | ribosomal protein L11 | 0.0352366 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0347861 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0346773 |
| FMNL2 | formin-like 2 | 0.0344587 |
| RPL37A | ribosomal protein L37a | 0.0331782 |
| PTMA | prothymosin, alpha | 0.0328905 |
| RPL3 | ribosomal protein L3 | 0.032447 |
| DSPP | dentin sialophosphoprotein | 0.0323281 |
| RPS6 | ribosomal protein S6 | 0.0317098 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0315906 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0301169 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.029628 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0295057 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0276933 |
| MMP12 | matrix metallopeptidase 12 | 0.0276243 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0275543 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0275431 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0274407 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0273722 |
| FAM13A | family with sequence similarity 13, member A | 0.0272869 |
| PCBP2 | poly(rC) binding protein 2 | 0.0271947 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0265095 |
| RPS3 | ribosomal protein S3 | 0.0265048 |
| PRELID2 | PRELI domain containing 2 | 0.0263722 |
| TPI1 | triosephosphate isomerase 1 | 0.0263375 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0260526 |
| HLA-A | major histocompatibility complex, class I, A | 0.025917 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0258564 |
| NBAS | neuroblastoma amplified sequence | 0.0256863 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0256853 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.025506 |
| FLNA | filamin A, alpha | 0.0253617 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0250694 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0245862 |
| RPS19 | ribosomal protein S19 | 0.0241791 |
| SERF2 | small EDRK-rich factor 2 | 0.0240591 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0236963 |
| NUP58 | nucleoporin 58 | 0.0233446 |
| G0S2 | G0/G1 switch 2 | 0.0231037 |
| RPL5 | ribosomal protein L5 | 0.0230556 |
| GOLGB1 | golgin B1 | 0.0224608 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0223484 |
| NAV2 | neuron navigator 2 | 0.022269 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0222195 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0222079 |
| TMF1 | TATA element modulatory factor 1 | 0.0221226 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0218152 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.021815 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0217472 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0217108 |
| MYO10 | myosin X | 0.0215898 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0214335 |
| RPL7 | ribosomal protein L7 | 0.0213672 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0212977 |
| RAI1 | retinoic acid induced 1 | 0.021096 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0209031 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0208843 |
| RPLP1 | ribosomal protein, large, P1 | 0.0208754 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0207773 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0207437 |
| RPS4X | ribosomal protein S4, X-linked | 0.0206557 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.020632 |
| CD63 | CD63 molecule | 0.0206297 |
| RPL35A | ribosomal protein L35a | 0.0205253 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0204802 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.209323 |
| CD44 | CD44 molecule (Indian blood group) | -0.0678548 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0611696 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0480541 |
| COL1A1 | collagen, type I, alpha 1 | -0.0478179 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0449124 |
| OSMR | oncostatin M receptor | -0.0442985 |
| INHBA | inhibin, beta A | -0.0415828 |
| HMGA2 | high mobility group AT-hook 2 | -0.0403941 |
| PLPP3 | phospholipid phosphatase 3 | -0.0395383 |
| ANKRD28 | ankyrin repeat domain 28 | -0.037408 |
| ATP13A3 | ATPase type 13A3 | -0.0369909 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0369739 |
| LOXL2 | lysyl oxidase-like 2 | -0.0363256 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.032925 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0326849 |
| MMP1 | matrix metallopeptidase 1 | -0.0313936 |
| EMP1 | epithelial membrane protein 1 | -0.0312237 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0302754 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0302016 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.028915 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0288549 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0286883 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0284339 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0279835 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.027337 |
| IER3 | immediate early response 3 | -0.027217 |
| RAI14 | retinoic acid induced 14 | -0.026569 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0261414 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0260183 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0256946 |
| CCND1 | cyclin D1 | -0.0251298 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0248409 |
| ACTG1 | actin gamma 1 | -0.0248176 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0242165 |
| FRMD4A | FERM domain containing 4A | -0.024165 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.02382 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.023727 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.023553 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0232291 |
| EGFR | epidermal growth factor receptor | -0.0229379 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0223007 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0219119 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0207312 |
| CDK17 | cyclin-dependent kinase 17 | -0.0204342 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0203769 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0203706 |
| TSHZ3 | teashirt zinc finger homeobox 3 | -0.019984 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0192138 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0191751 |
| RTN4 | reticulon 4 | -0.0189731 |
| AHNAK | AHNAK nucleoprotein | -0.0184582 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0183634 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.018329 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | -0.0180143 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0179524 |
| VCL | vinculin | -0.0175991 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0175104 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0174895 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0170684 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0168798 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0164409 |
| STC1 | stanniocalcin 1 | -0.0162877 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0160433 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0157729 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0156057 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.015166 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0150944 |
| FOXP1 | forkhead box P1 | -0.0150922 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0150687 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0149389 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0149136 |
| PALLD | palladin, cytoskeletal associated protein | -0.0148775 |
| NRP1 | neuropilin 1 | -0.0144743 |
| SMAD3 | SMAD family member 3 | -0.01444 |
| CCDC102B | coiled-coil domain containing 102B | -0.0144145 |
| ARF1 | ADP-ribosylation factor 1 | -0.0143193 |
| JMJD1C | jumonji domain containing 1C | -0.0143092 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.014269 |
| PARVA | parvin, alpha | -0.0141855 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0140032 |
| RPS24 | ribosomal protein S24 | -0.0138171 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.013703 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0134088 |
| TNPO1 | transportin 1 | -0.0133907 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0133772 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0133648 |
| RUNX1 | runt-related transcription factor 1 | -0.0133346 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0132306 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0131474 |
| SOCS5 | suppressor of cytokine signaling 5 | -0.0130967 |
| ASPH | aspartate beta-hydroxylase | -0.0130838 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | -0.0130276 |
| TMEM263 | transmembrane protein 263 | -0.0129592 |
| RHOQ | ras homolog family member Q | -0.0129462 |
| ANXA2 | annexin A2 | -0.0129452 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0129161 |
| JAK1 | Janus kinase 1 | -0.0127167 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0125047 |
| HAS2 | hyaluronan synthase 2 | -0.0123519 |
