Lichen Planus Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A lichen disease that is located_in skin, located_in tongue or located_in oral mucosa, which presents itself in the form of papules, lesions or rashes. The cause is not known. (Human Disease Ontology, DOID_9201)
External Link https://www.disgenet.org/browser/0/1/0/C0023645
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Genes

281 genes associated with the disease Lichen Planus in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AANAT aralkylamine N-acetyltransferase
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACTB actin, beta
ACVRL1 activin A receptor type II-like 1
ADM adrenomedullin
AGER advanced glycosylation end product-specific receptor
AIM2 absent in melanoma 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
APOB apolipoprotein B
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOL2 apolipoprotein L, 2
ATG9B autophagy related 9B
AWAT2 acyl-CoA wax alcohol acyltransferase 2
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BCL9L B-cell CLL/lymphoma 9-like
BGN biglycan
BSG basigin (Ok blood group)
BUB3 BUB3 mitotic checkpoint protein
C5AR1 complement component 5a receptor 1
CALML3 calmodulin-like 3
CAMP cathelicidin antimicrobial peptide
CARD18 caspase recruitment domain family, member 18
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL17 chemokine (C-C motif) ligand 17
CCL2 chemokine (C-C motif) ligand 2
CCL27 chemokine (C-C motif) ligand 27
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD1A CD1a molecule
CD274 CD274 molecule
CD34 CD34 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CD68 CD68 molecule
CD86 CD86 molecule
CDA cytidine deaminase
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CIITA class II, major histocompatibility complex, transactivator
CKAP4 cytoskeleton-associated protein 4
CLDN1 claudin 1
CLDN4 claudin 4
CLDN7 claudin 7
CLEC4C C-type lectin domain family 4, member C
COL17A1 collagen, type XVII, alpha 1
COTL1 coactosin-like F-actin binding protein 1
COX2
COX5A cytochrome c oxidase subunit Va
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CPOX coproporphyrinogen oxidase
CRH corticotropin releasing hormone
CRHR1 corticotropin releasing hormone receptor 1
CRP C-reactive protein, pentraxin-related
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CST2 cystatin SA
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTRL chymotrypsin-like
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR3 chemokine (C-X-C motif) receptor 3
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DCD dermcidin
DDIT4 DNA-damage-inducible transcript 4
DEFB1 defensin, beta 1
DEFB4A defensin, beta 4A
DEFB4B defensin, beta 4B
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DSC1 desmocollin 1
DSG1 desmoglein 1
DSG3 desmoglein 3
DUOX1 dual oxidase 1
EBI3 Epstein-Barr virus induced 3
EGFR epidermal growth factor receptor
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELANE elastase, neutrophil expressed
ERBB2 erb-b2 receptor tyrosine kinase 2
ERVW-1 endogenous retrovirus group W, member 1
F11R F11 receptor
FLG filaggrin
FLT4 fms-related tyrosine kinase 4
FOXP3 forkhead box P3
GATA3 GATA binding protein 3
GEM GTP binding protein overexpressed in skeletal muscle
GMPS guanine monphosphate synthase
GNLY granulysin
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAVCR2 hepatitis A virus cellular receptor 2
HDAC7 histone deacetylase 7
HES1 hes family bHLH transcription factor 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-C major histocompatibility complex, class I, C
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HMGB4 high mobility group box 4
HNMT histamine N-methyltransferase
HOPX HOP homeobox
HP haptoglobin
HRH4 histamine receptor H4
HTN1 histatin 1
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP4 insulin-like growth factor binding protein 4
IL10 interleukin 10
IL12A interleukin 12A
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL21 interleukin 21
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL25 interleukin 25
IL2RA interleukin 2 receptor, alpha
IL31 interleukin 31
IL33 interleukin 33
IL4 interleukin 4
IL6 interleukin 6
IL9 interleukin 9
IRF7 interferon regulatory factor 7
ISG20 interferon stimulated exonuclease gene 20kDa
ITGA11 integrin, alpha 11
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
IVL involucrin
JAK1 Janus kinase 1
JAK2 Janus kinase 2
KDR kinase insert domain receptor
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KRT15 keratin 15, type I
KRT19 keratin 19, type I
KRT20 keratin 20, type I
LAMP1 lysosomal-associated membrane protein 1
LBR lamin B receptor
LCN2 lipocalin 2
LGALS3 lectin, galactoside-binding, soluble, 3
LTA lymphotoxin alpha
LUM lumican
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAPK3 mitogen-activated protein kinase 3
MARCKSL1 MARCKS-like 1
MBL2 mannose-binding lectin (protein C) 2, soluble
MCAM melanoma cell adhesion molecule
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MGC57346-CRHR1 MGC57346-CRHR1 readthrough
MGMT O-6-methylguanine-DNA methyltransferase
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MOK MOK protein kinase
MPO myeloperoxidase
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYDGF myeloid-derived growth factor
NCAM1 neural cell adhesion molecule 1
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NLRP3 NLR family, pyrin domain containing 3
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NR5A1 nuclear receptor subfamily 5, group A, member 1
NRP2 neuropilin 2
NT5C2 5'-nucleotidase, cytosolic II
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
PCNA proliferating cell nuclear antigen
PDC phosducin
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PDE4B phosphodiesterase 4B, cAMP-specific
PDPN podoplanin
PECAM1 platelet/endothelial cell adhesion molecule 1
PER2 period circadian clock 2
PLD2 phospholipase D2
PLK2 polo-like kinase 2
POSTN periostin, osteoblast specific factor
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPIG peptidylprolyl isomerase G (cyclophilin G)
PRL prolactin
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAD51 RAD51 recombinase
RBM45 RNA binding motif protein 45
RHO rhodopsin
RPE65 retinal pigment epithelium-specific protein 65kDa
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SDC1 syndecan 1
SELE selectin E
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SLC12A9 solute carrier family 12, member 9
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLPI secretory leukocyte peptidase inhibitor
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX4 SRY (sex determining region Y)-box 4
SPP1 secreted phosphoprotein 1
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIM1 stromal interaction molecule 1
SUMO1 small ubiquitin-like modifier 1
SYNE1 spectrin repeat containing, nuclear envelope 1
TAS2R13 taste receptor, type 2, member 13
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TCHHL1 trichohyalin-like 1
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
TGM1 transglutaminase 1
TGM2 transglutaminase 2
TGM3 transglutaminase 3
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR8 toll-like receptor 8
TNC tenascin C
TNF tumor necrosis factor
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNNC1 troponin C type 1 (slow)
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP63 tumor protein p63
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIB3 tribbles pseudokinase 3
TRIM21 tripartite motif containing 21
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSHR thyroid stimulating hormone receptor
TSLP thymic stromal lymphopoietin
TSPAN33 tetraspanin 33
TWIST1 twist family bHLH transcription factor 1
ULK1 unc-51 like autophagy activating kinase 1
UVRAG UV radiation resistance associated
VAMP4 vesicle-associated membrane protein 4
VASH1 vasohibin 1
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIM vimentin
WLS wntless Wnt ligand secretion mediator
WNT5A wingless-type MMTV integration site family, member 5A
YME1L1 YME1-like 1 ATPase
ZEB1 zinc finger E-box binding homeobox 1