| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lidocaine (hydrochloride)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.157788 |
| EXT1 | exostosin glycosyltransferase 1 | 0.129043 |
| ASPH | aspartate beta-hydroxylase | 0.115935 |
| SMAD3 | SMAD family member 3 | 0.0983932 |
| CD44 | CD44 molecule (Indian blood group) | 0.0905718 |
| GPC6 | glypican 6 | 0.0888273 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0737618 |
| RNF213 | ring finger protein 213 | 0.0693757 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0602184 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0600275 |
| GLIS3 | GLIS family zinc finger 3 | 0.0579658 |
| SEPTIN9 | septin 9 | 0.0571372 |
| NAV2 | neuron navigator 2 | 0.0551747 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0545474 |
| TXNRD1 | thioredoxin reductase 1 | 0.0530457 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0526384 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0517869 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0516207 |
| KYNU | kynureninase | 0.0508237 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0477665 |
| APOL1 | apolipoprotein L, 1 | 0.0471299 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0462463 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0458649 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0445993 |
| PLEC | plectin | 0.0427497 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0426304 |
| NRP2 | neuropilin 2 | 0.0423522 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0419338 |
| MSN | moesin | 0.0387077 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0379066 |
| PDLIM5 | PDZ and LIM domain 5 | 0.037774 |
| FAT1 | FAT atypical cadherin 1 | 0.0373099 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.037186 |
| FRMD4A | FERM domain containing 4A | 0.0359555 |
| VCL | vinculin | 0.0359397 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0355548 |
| APP | amyloid beta (A4) precursor protein | 0.0349542 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0349068 |
| EGFR | epidermal growth factor receptor | 0.034721 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0337224 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0330905 |
| CA12 | carbonic anhydrase XII | 0.0326572 |
| OSMR | oncostatin M receptor | 0.032297 |
| MX1 | MX dynamin-like GTPase 1 | 0.0322485 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0320815 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0320043 |
| RPL3 | ribosomal protein L3 | 0.0314103 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0313641 |
| RRM2 | ribonucleotide reductase M2 | 0.0310019 |
| HPS3 | Hermansky-Pudlak syndrome 3 | 0.0304142 |
| CMIP | c-Maf inducing protein | 0.0301225 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0297908 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0295643 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0294227 |
| JAK1 | Janus kinase 1 | 0.0293422 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0290592 |
| ADAR | adenosine deaminase, RNA-specific | 0.0289378 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0289354 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0288889 |
| EXOC4 | exocyst complex component 4 | 0.0286382 |
| ACTN4 | actinin, alpha 4 | 0.0280172 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0279055 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.027821 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.027409 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0269332 |
| FLNB | filamin B, beta | 0.0267657 |
| FLNA | filamin A, alpha | 0.0263902 |
| MYOF | myoferlin | 0.0262308 |
| TGM2 | transglutaminase 2 | 0.0261876 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0261253 |
| HDAC9 | histone deacetylase 9 | 0.0259006 |
| RPS4X | ribosomal protein S4, X-linked | 0.0257792 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0257621 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0251752 |
| NRP1 | neuropilin 1 | 0.0251287 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.025048 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0248905 |
| EFNA5 | ephrin-A5 | 0.0248747 |
| AHNAK | AHNAK nucleoprotein | 0.0247299 |
| MYO1E | myosin IE | 0.0247255 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0247251 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0246504 |
| BPTF | bromodomain PHD finger transcription factor | 0.0244791 |
| INTS6 | integrator complex subunit 6 | 0.0241115 |
| CTBP2 | C-terminal binding protein 2 | 0.0240678 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.023936 |
| MRTFA | myocardin related transcription factor A | 0.0236749 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0236052 |
| RUNX1 | runt-related transcription factor 1 | 0.0235651 |
| LOXL2 | lysyl oxidase-like 2 | 0.0233962 |
| C1S | complement component 1, s subcomponent | 0.0231073 |
| NFIB | nuclear factor I/B | 0.0230471 |
| ARRDC3 | arrestin domain containing 3 | 0.0230193 |
| CUX1 | cut-like homeobox 1 | 0.0225791 |
| CENPF | centromere protein F, 350/400kDa | 0.0224266 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0222538 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0221836 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0220811 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0220136 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0219873 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.251255 |
| VIM | vimentin | -0.109237 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0834015 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0801543 |
| TMSB10 | thymosin beta 10 | -0.0753872 |
| RPL35A | ribosomal protein L35a | -0.059083 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0567359 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0516456 |
| FTL | ferritin, light polypeptide | -0.0471303 |
| NDRG1 | N-myc downstream regulated 1 | -0.0439401 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0428222 |
| CP | ceruloplasmin (ferroxidase) | -0.0414915 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0381696 |
| PLIN2 | perilipin 2 | -0.03772 |
| PTMA | prothymosin, alpha | -0.0357234 |
| RPS6 | ribosomal protein S6 | -0.0350177 |
| CADM1 | cell adhesion molecule 1 | -0.0332432 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0330732 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0310858 |
| HMGB1 | high mobility group box 1 | -0.0309899 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0308013 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0307025 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0289095 |
| GOLGA4 | golgin A4 | -0.0285585 |
| CANX | calnexin | -0.0285141 |
| GDF15 | growth differentiation factor 15 | -0.0284483 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0268929 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.025881 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0254841 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0241494 |
| ANXA5 | annexin A5 | -0.0239722 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0239202 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0235504 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0234493 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0231834 |
| SDCBP | syndecan binding protein (syntenin) | -0.0228007 |
| POTEF | POTE ankyrin domain family, member F | -0.0219921 |
| HMGA1 | high mobility group AT-hook 1 | -0.0218448 |
| TMEM263 | transmembrane protein 263 | -0.0216078 |
| RPL34 | ribosomal protein L34 | -0.0215134 |
| TPM4 | tropomyosin 4 | -0.0214654 |
| NOP58 | NOP58 ribonucleoprotein | -0.021396 |
| USP3 | ubiquitin specific peptidase 3 | -0.0213803 |
| INSIG1 | insulin induced gene 1 | -0.0213394 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0212909 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0212159 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0206974 |
| RND3 | Rho family GTPase 3 | -0.0206665 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0203624 |
| RAB2A | RAB2A, member RAS oncogene family | -0.020307 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | -0.0200467 |
| TFG | TRK-fused gene | -0.0200299 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0196142 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0194511 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0194431 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0190424 |
| SCFD2 | sec1 family domain containing 2 | -0.0187754 |
| SEPTIN7 | septin 7 | -0.0187043 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0185951 |
| PFN1 | profilin 1 | -0.0184827 |
| LAMB3 | laminin, beta 3 | -0.0184597 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0184469 |
| HBP1 | HMG-box transcription factor 1 | -0.0182479 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0182346 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0182131 |
| RBM39 | RNA binding motif protein 39 | -0.0180883 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0180214 |
| S100A6 | S100 calcium binding protein A6 | -0.0178609 |
| TRAM1 | translocation associated membrane protein 1 | -0.0176214 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0175107 |
| ATP13A3 | ATPase type 13A3 | -0.0174464 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0173754 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0172677 |
| MATR3 | matrin 3 | -0.0172642 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0172096 |
| RPS19 | ribosomal protein S19 | -0.0171491 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0171035 |
| DENND4C | DENN/MADD domain containing 4C | -0.0170303 |
| RPLP1 | ribosomal protein, large, P1 | -0.0169072 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0168491 |
| FBXO32 | F-box protein 32 | -0.0167406 |
| SPAG9 | sperm associated antigen 9 | -0.016733 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0167188 |
| TPM1 | tropomyosin 1 (alpha) | -0.0161774 |
| ADM | adrenomedullin | -0.0161652 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0161076 |
| GNAS | GNAS complex locus | -0.0160999 |
| FN1 | fibronectin 1 | -0.0158716 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0158323 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0158109 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0156373 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -0.0154881 |
| MORF4L2 | mortality factor 4 like 2 | -0.0152562 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0150486 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0149123 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0149066 |
| JMJD1C | jumonji domain containing 1C | -0.0148678 |
| WDR43 | WD repeat domain 43 | -0.014854 |
| MTDH | metadherin | -0.014805 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0146217 |
