| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.25248 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.137956 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.135205 |
| HMGA2 | high mobility group AT-hook 2 | 0.134535 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0940496 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0756939 |
| GSE1 | Gse1 coiled-coil protein | 0.0733566 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0711146 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.064307 |
| PDE10A | phosphodiesterase 10A | 0.0642128 |
| H1-4 | H1.4 linker histone, cluster member | 0.0642119 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0636423 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0624771 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0586313 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0571445 |
| MEST | mesoderm specific transcript | 0.0569166 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0557353 |
| CENPF | centromere protein F, 350/400kDa | 0.0547646 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0544965 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0543889 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0518617 |
| RAD51B | RAD51 paralog B | 0.0515413 |
| ACTG1 | actin gamma 1 | 0.0514836 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0509531 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0502866 |
| FNIP1 | folliculin interacting protein 1 | 0.0484568 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.048133 |
| CTBP2 | C-terminal binding protein 2 | 0.0477654 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0471998 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0470367 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0467983 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0455727 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.045342 |
| TPI1 | triosephosphate isomerase 1 | 0.0451834 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0443589 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0442306 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.043817 |
| NSD3 | nuclear receptor binding SET domain protein 3 | 0.0434874 |
| FLNA | filamin A, alpha | 0.0429827 |
| ATP11A | ATPase, class VI, type 11A | 0.0426124 |
| RPL3 | ribosomal protein L3 | 0.0418323 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0404699 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0402211 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0393675 |
| EXOC6B | exocyst complex component 6B | 0.0392662 |
| PRELID2 | PRELI domain containing 2 | 0.039235 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0387298 |
| CADM2 | cell adhesion molecule 2 | 0.0386572 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0375608 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0373741 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.037271 |
| USP34 | ubiquitin specific peptidase 34 | 0.0365068 |
| BRD2 | bromodomain containing 2 | 0.0363415 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0361055 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0357677 |
| ZNF608 | zinc finger protein 608 | 0.035301 |
| CCNG2 | cyclin G2 | 0.0352221 |
| TOP1 | topoisomerase (DNA) I | 0.0348907 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0341734 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0337805 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0335216 |
| ZNF516 | zinc finger protein 516 | 0.0334034 |
| UST | uronyl-2-sulfotransferase | 0.0333488 |
| EGFR | epidermal growth factor receptor | 0.033242 |
| GTF2I | general transcription factor IIi | 0.033011 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.032614 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0322642 |
| WWC2 | WW and C2 domain containing 2 | 0.0320942 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.032001 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0316937 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0314184 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0313103 |
| EZR | ezrin | 0.0311564 |
| HDLBP | high density lipoprotein binding protein | 0.0308828 |
| RPS18 | ribosomal protein S18 | 0.0307737 |
| MYOF | myoferlin | 0.0302826 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0301578 |
| BCOR | BCL6 corepressor | 0.0300106 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.029962 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.029948 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0297607 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0295147 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0294078 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0294043 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0290891 |
| PANK3 | pantothenate kinase 3 | 0.0290688 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0289407 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0287224 |
| CENPE | centromere protein E, 312kDa | 0.0285239 |
| RPS4X | ribosomal protein S4, X-linked | 0.0284802 |
| RPS11 | ribosomal protein S11 | 0.028422 |
| ERBIN | erbb2 interacting protein | 0.0281585 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0281207 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0279169 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0277349 |
| PCDH7 | protocadherin 7 | 0.0277279 |
| KIAA0232 | KIAA0232 | 0.0274301 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0273011 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0272667 |
| FUS | FUS RNA binding protein | 0.0270945 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.0914349 |
| MGP | matrix Gla protein | -0.0640832 |
| MT2A | metallothionein 2A | -0.0596573 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0564648 |
| RPL35A | ribosomal protein L35a | -0.0529063 |
| COL1A2 | collagen, type I, alpha 2 | -0.0515785 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.049176 |
| TMSB10 | thymosin beta 10 | -0.0476172 |
| ZNF292 | zinc finger protein 292 | -0.0473172 |
| RBM39 | RNA binding motif protein 39 | -0.0429469 |
| RPLP1 | ribosomal protein, large, P1 | -0.0424238 |
| MATR3 | matrin 3 | -0.0416382 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0366139 |
| YBX1 | Y box binding protein 1 | -0.0344876 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0338232 |
| RPL34 | ribosomal protein L34 | -0.0322631 |
| RPLP2 | ribosomal protein, large, P2 | -0.0311519 |
| CLINT1 | clathrin interactor 1 | -0.0302351 |
| SRPK2 | SRSF protein kinase 2 | -0.0301725 |
| RPS8 | ribosomal protein S8 | -0.0299931 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0297398 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.02945 |
| RPS19 | ribosomal protein S19 | -0.0292833 |
| NDRG1 | N-myc downstream regulated 1 | -0.0289833 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0288452 |
| RPS6 | ribosomal protein S6 | -0.0283336 |
| MEOX2 | mesenchyme homeobox 2 | -0.0283025 |
| RNF145 | ring finger protein 145 | -0.028115 |
| TPM4 | tropomyosin 4 | -0.0279777 |
| HMGB1 | high mobility group box 1 | -0.0265718 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0252278 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.025029 |
| CANX | calnexin | -0.0249441 |
| RPL37A | ribosomal protein L37a | -0.0247171 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0246879 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | -0.0244676 |
| WDR43 | WD repeat domain 43 | -0.0244362 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0241214 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0241122 |
| MAP1B | microtubule-associated protein 1B | -0.024023 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0237565 |
| RPS29 | ribosomal protein S29 | -0.0236989 |
| ZFR | zinc finger RNA binding protein | -0.0236477 |
| RPL31 | ribosomal protein L31 | -0.0235993 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0230647 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0227448 |
| NOP58 | NOP58 ribonucleoprotein | -0.0226985 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0223696 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0223618 |
| SREK1IP1 | SREK1-interacting protein 1 | -0.0218255 |
| USP24 | ubiquitin specific peptidase 24 | -0.0216825 |
| MORF4L1 | mortality factor 4 like 1 | -0.0215721 |
| WDR45B | WD repeat domain 45B | -0.0215566 |
| HMGA1 | high mobility group AT-hook 1 | -0.0213418 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0212515 |
| CBX1 | chromobox homolog 1 | -0.02113 |
| USP33 | ubiquitin specific peptidase 33 | -0.0210427 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | -0.0209619 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0209081 |
| POMP | proteasome maturation protein | -0.0209042 |
| HLA-B | major histocompatibility complex, class I, B | -0.020604 |
| FAM168A | family with sequence similarity 168, member A | -0.0204784 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0204375 |
| RPS14 | ribosomal protein S14 | -0.0203596 |
| HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | -0.0202352 |
| RPL27 | ribosomal protein L27 | -0.0200535 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0199434 |
| ANXA5 | annexin A5 | -0.0199411 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0198576 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0197044 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0195031 |
| CCNL1 | cyclin L1 | -0.0194317 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0194039 |
| RPL12 | ribosomal protein L12 | -0.0193079 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0192459 |
| USP3 | ubiquitin specific peptidase 3 | -0.0192293 |
| KIF2A | kinesin heavy chain member 2A | -0.0190425 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0190148 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0189757 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.0189516 |
| CBX3 | chromobox homolog 3 | -0.0189085 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0189014 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0188722 |
| NBAS | neuroblastoma amplified sequence | -0.0187998 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0187063 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0181799 |
| TBC1D12 | TBC1 domain family, member 12 | -0.0181579 |
| TPD52 | tumor protein D52 | -0.0181265 |
| FTL | ferritin, light polypeptide | -0.0179921 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | -0.0179497 |
| NUP58 | nucleoporin 58 | -0.0178845 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0178369 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0177659 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0175142 |
| SHISA3 | shisa family member 3 | -0.0175083 |
| RPS2 | ribosomal protein S2 | -0.0173745 |
| RTN4 | reticulon 4 | -0.0172359 |
| INSIG2 | insulin induced gene 2 | -0.0171159 |
| CD63 | CD63 molecule | -0.0170177 |
| NDC1 | NDC1 transmembrane nucleoporin | -0.016851 |
