| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLEC | plectin | 0.194517 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.194141 |
| FLNB | filamin B, beta | 0.178742 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.125481 |
| LAMC2 | laminin, gamma 2 | 0.117591 |
| AHNAK | AHNAK nucleoprotein | 0.115957 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.100526 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0964934 |
| POTEF | POTE ankyrin domain family, member F | 0.0873473 |
| UBC | ubiquitin C | 0.0825298 |
| LAMA4 | laminin, alpha 4 | 0.082177 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0797602 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0778419 |
| HMGA2 | high mobility group AT-hook 2 | 0.0764436 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.075658 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0721793 |
| KLK10 | kallikrein-related peptidase 10 | 0.0704904 |
| MUC17 | mucin 17, cell surface associated | 0.0694934 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0684613 |
| DSPP | dentin sialophosphoprotein | 0.0680411 |
| RASAL2 | RAS protein activator like 2 | 0.0649848 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0647296 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0646355 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0638123 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0631688 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0629091 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0608009 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0604732 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.059746 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0592285 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0589706 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0587248 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0586554 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0569234 |
| CD44 | CD44 molecule (Indian blood group) | 0.0544278 |
| TXNIP | thioredoxin interacting protein | 0.0536374 |
| MYOF | myoferlin | 0.0522477 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0513335 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.051102 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0507889 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0472739 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0472724 |
| CORO1C | coronin, actin binding protein, 1C | 0.0472449 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0471255 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0470833 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0469489 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0453724 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0445335 |
| NDRG1 | N-myc downstream regulated 1 | 0.0439227 |
| HDAC9 | histone deacetylase 9 | 0.042311 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0411206 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0400816 |
| MSN | moesin | 0.038591 |
| ACTN4 | actinin, alpha 4 | 0.0384254 |
| FLNA | filamin A, alpha | 0.0382598 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0369819 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0369235 |
| ANXA2 | annexin A2 | 0.0365539 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0364561 |
| NPSR1 | neuropeptide S receptor 1 | 0.0363359 |
| ITGA6 | integrin, alpha 6 | 0.036196 |
| RPL3 | ribosomal protein L3 | 0.0354673 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.035198 |
| SEPTIN9 | septin 9 | 0.034867 |
| ERBIN | erbb2 interacting protein | 0.0344625 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0331114 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0329343 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.032602 |
| LDHA | lactate dehydrogenase A | 0.0323351 |
| TGM2 | transglutaminase 2 | 0.0316713 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0314616 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0314384 |
| HDLBP | high density lipoprotein binding protein | 0.0309244 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0306615 |
| PARD6B | par-6 family cell polarity regulator beta | 0.0306491 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.030625 |
| TMEM164 | transmembrane protein 164 | 0.029674 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.029616 |
| CAB39 | calcium binding protein 39 | 0.0295306 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0292172 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0286391 |
| EGFR | epidermal growth factor receptor | 0.0285767 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0285211 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.028409 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0283629 |
| DSG2 | desmoglein 2 | 0.0280521 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0279765 |
| RCOR1 | REST corepressor 1 | 0.0278515 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0278097 |
| INTS6 | integrator complex subunit 6 | 0.027773 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0275318 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0267041 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0266202 |
| SDC1 | syndecan 1 | 0.0265395 |
| SGMS2 | sphingomyelin synthase 2 | 0.0264947 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0263245 |
| EFNB2 | ephrin-B2 | 0.0263057 |
| GOLGA3 | golgin A3 | 0.0262318 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0259482 |
| S100A10 | S100 calcium binding protein A10 | 0.0258155 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.143202 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.141105 |
| FTL | ferritin, light polypeptide | -0.0913319 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0803191 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.071703 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0660047 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0619244 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0595564 |
| LMO7 | LIM domain 7 | -0.0591552 |
| HMGA1 | high mobility group AT-hook 1 | -0.0574818 |
| B2M | beta-2-microglobulin | -0.0555848 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0538847 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0527074 |
| RPL35A | ribosomal protein L35a | -0.0507581 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0441483 |
| TPM4 | tropomyosin 4 | -0.0426414 |
| PTMA | prothymosin, alpha | -0.0419769 |
| STK39 | serine threonine kinase 39 | -0.0400103 |
| ARF4 | ADP-ribosylation factor 4 | -0.0387274 |
| MTDH | metadherin | -0.0379514 |
| CLMP | CXADR-like membrane protein | -0.0376893 |
| RPS27 | ribosomal protein S27 | -0.0373062 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0368994 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0359255 |
| HLA-A | major histocompatibility complex, class I, A | -0.0359157 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0352489 |
| RPLP1 | ribosomal protein, large, P1 | -0.0350509 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0349776 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0348526 |
| RPS13 | ribosomal protein S13 | -0.0346931 |
| RPL34 | ribosomal protein L34 | -0.0339954 |
| SLMAP | sarcolemma associated protein | -0.0339423 |
| RPS8 | ribosomal protein S8 | -0.0315235 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0312832 |
| GNAS | GNAS complex locus | -0.0312351 |
| FAM107B | family with sequence similarity 107, member B | -0.0308312 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0303927 |
| TXNRD1 | thioredoxin reductase 1 | -0.0301701 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0299692 |
| KIF5B | kinesin family member 5B | -0.0295859 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0295406 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0290791 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0288134 |
| JMJD1C | jumonji domain containing 1C | -0.0284483 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0281394 |
| RPS6 | ribosomal protein S6 | -0.0280839 |
| FNBP4 | formin binding protein 4 | -0.0279561 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0279336 |
| RPL37A | ribosomal protein L37a | -0.0278876 |
| S100A6 | S100 calcium binding protein A6 | -0.0275705 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.027323 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0269767 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0267365 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0266397 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0263605 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.026349 |
| RPL27A | ribosomal protein L27a | -0.0261319 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.025714 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0254274 |
| OXR1 | oxidation resistance 1 | -0.0249065 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0247488 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0245269 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0244395 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.024229 |
| SEPTIN7 | septin 7 | -0.024105 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.023865 |
| TXNDC11 | thioredoxin domain containing 11 | -0.0238176 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.023775 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.023712 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0234521 |
| LUC7L | LUC7-like (S. cerevisiae) | -0.0234304 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0233708 |
| NCOA3 | nuclear receptor coactivator 3 | -0.023348 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0233396 |
| RPS21 | ribosomal protein S21 | -0.0228695 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0224542 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0224531 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0223095 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0221834 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0221118 |
| TMC5 | transmembrane channel-like 5 | -0.0218456 |
| MACO1 | macoilin 1 | -0.0217309 |
| CANX | calnexin | -0.0215928 |
| TAOK3 | TAO kinase 3 | -0.0211636 |
| GOLGA4 | golgin A4 | -0.0211292 |
| THOC2 | THO complex 2 | -0.0209928 |
| CDCP1 | CUB domain containing protein 1 | -0.0208689 |
| NEK7 | NIMA-related kinase 7 | -0.020753 |
| WASF2 | WAS protein family, member 2 | -0.020432 |
| RPL31 | ribosomal protein L31 | -0.0203742 |
| USP3 | ubiquitin specific peptidase 3 | -0.0202728 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0202685 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0200712 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0200345 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0200344 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | -0.02001 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0199971 |
| RESF1 | retroelement silencing factor 1 | -0.0199509 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0198383 |
| YME1L1 | YME1-like 1 ATPase | -0.0198058 |
