| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.222914 |
| ZNF608 | zinc finger protein 608 | 0.174369 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.160544 |
| VCL | vinculin | 0.147285 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.115909 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.114135 |
| TOX | thymocyte selection-associated high mobility group box | 0.108954 |
| DST | dystonin | 0.106685 |
| RPL3 | ribosomal protein L3 | 0.0912962 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0870013 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0853071 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0833735 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0832184 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0774756 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0770996 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0739436 |
| NFIA | nuclear factor I/A | 0.0708143 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0682678 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.066867 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0627371 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0607629 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0602891 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0580015 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0577489 |
| JMJD1C | jumonji domain containing 1C | 0.0566799 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0564325 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0553628 |
| ATP9A | ATPase, class II, type 9A | 0.0546282 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0538797 |
| USP34 | ubiquitin specific peptidase 34 | 0.0532487 |
| VMP1 | vacuole membrane protein 1 | 0.0530025 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0527737 |
| RCC1 | regulator of chromosome condensation 1 | 0.0517992 |
| BNC2 | basonuclin 2 | 0.0516481 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0514878 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0477917 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0467889 |
| MLIP | muscular LMNA-interacting protein | 0.0465354 |
| H1-4 | H1.4 linker histone, cluster member | 0.0462231 |
| CNN2 | calponin 2 | 0.0453175 |
| MED13 | mediator complex subunit 13 | 0.0449018 |
| SIK3 | SIK family kinase 3 | 0.0439794 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.043767 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0432495 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0426736 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0423004 |
| CREBBP | CREB binding protein | 0.0414834 |
| PCM1 | pericentriolar material 1 | 0.0414711 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0413433 |
| WLS | wntless Wnt ligand secretion mediator | 0.0412592 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0411318 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0409405 |
| ATP11A | ATPase, class VI, type 11A | 0.0404983 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0403989 |
| UBAP2 | ubiquitin associated protein 2 | 0.0397584 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0396753 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0395771 |
| FERMT2 | fermitin family member 2 | 0.0386806 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0386415 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0378893 |
| SETD5 | SET domain containing 5 | 0.0378726 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0375029 |
| RPS4X | ribosomal protein S4, X-linked | 0.0373853 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0373714 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0370356 |
| TENM3 | teneurin transmembrane protein 3 | 0.0368014 |
| FLNA | filamin A, alpha | 0.0367758 |
| BRD2 | bromodomain containing 2 | 0.0367156 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0366696 |
| SNX14 | sorting nexin 14 | 0.0363894 |
| HDLBP | high density lipoprotein binding protein | 0.0362964 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0360339 |
| PHF21A | PHD finger protein 21A | 0.0356531 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0353146 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0348909 |
| GNAS | GNAS complex locus | 0.0348379 |
| RPL13A | ribosomal protein L13a | 0.0347568 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.03472 |
| ARMH4 | armadillo like helical domain containing 4 | 0.0343879 |
| EFNA5 | ephrin-A5 | 0.0339071 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0336538 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0335915 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0333886 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0332369 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0330193 |
| H1-0 | H1.0 linker histone | 0.032506 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0324581 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0323276 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0319246 |
| CCDC88A | coiled-coil domain containing 88A | 0.0317859 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0316035 |
| UBC | ubiquitin C | 0.0315476 |
| PCBP2 | poly(rC) binding protein 2 | 0.0313118 |
| NFIB | nuclear factor I/B | 0.0312352 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0311955 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0305347 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0304466 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0302609 |
| NBEAL1 | neurobeachin-like 1 | 0.0300539 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.02989 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.113521 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.113294 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0458432 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0389343 |
| HMGA1 | high mobility group AT-hook 1 | -0.0372916 |
| RPS21 | ribosomal protein S21 | -0.0349802 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0341314 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.033061 |
| ACACA | acetyl-CoA carboxylase alpha | -0.031985 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0296601 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0269746 |
| PTMA | prothymosin, alpha | -0.0267883 |
| RIGI | RNA sensor RIG-I | -0.0264702 |
| RPL12 | ribosomal protein L12 | -0.0264136 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0263695 |
| TMX3 | thioredoxin-related transmembrane protein 3 | -0.0262274 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0261337 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0252469 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0249669 |
| ACTG1 | actin gamma 1 | -0.0235487 |
| TMSB10 | thymosin beta 10 | -0.0230304 |
| RPLP1 | ribosomal protein, large, P1 | -0.0224314 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0221695 |
| SMYD3 | SET and MYND domain containing 3 | -0.0215377 |
| NEBL | nebulette | -0.0214993 |
| EMP1 | epithelial membrane protein 1 | -0.0207031 |
| FNBP4 | formin binding protein 4 | -0.0199081 |
| ZFP64 | ZFP64 zinc finger protein | -0.0192987 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.018703 |
| FAM117B | family with sequence similarity 117, member B | -0.0181772 |
| TXNRD1 | thioredoxin reductase 1 | -0.0179765 |
| RPL35A | ribosomal protein L35a | -0.0177707 |
| RANBP17 | RAN binding protein 17 | -0.0175823 |
| RPL22 | ribosomal protein L22 | -0.0175146 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0168527 |
| MTAP | methylthioadenosine phosphorylase | -0.0167757 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0167301 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.016689 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0166145 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0165699 |
| CPA6 | carboxypeptidase A6 | -0.0162877 |
| RPL30 | ribosomal protein L30 | -0.0162768 |
| ZFR | zinc finger RNA binding protein | -0.0162356 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0161824 |
| YEATS2 | YEATS domain containing 2 | -0.0161323 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0160862 |
| CDV3 | CDV3 homolog (mouse) | -0.0160075 |
| CBX3 | chromobox homolog 3 | -0.0158333 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0158204 |
| TMEM117 | transmembrane protein 117 | -0.0158061 |
| WDR43 | WD repeat domain 43 | -0.015795 |
| BRI3BP | BRI3 binding protein | -0.015724 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0155932 |
| EWSR1 | EWS RNA-binding protein 1 | -0.0154733 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0152733 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0149463 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0148679 |
| MAP4 | microtubule-associated protein 4 | -0.0146341 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) | -0.0146184 |
| CA5B | carbonic anhydrase VB, mitochondrial | -0.0145449 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0145014 |
| CFAP97 | cilia and flagella associated protein 97 | -0.0143415 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0142272 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0139546 |
| MRPS27 | mitochondrial ribosomal protein S27 | -0.0138735 |
| WDR27 | WD repeat domain 27 | -0.0138668 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0138395 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0137812 |
| ANXA2 | annexin A2 | -0.0137781 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | -0.0136272 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0136108 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.01357 |
| TUBA1C | tubulin, alpha 1c | -0.0134702 |
| R3HDM1 | R3H domain containing 1 | -0.0133316 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0132966 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0132327 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.013202 |
| KIAA1671 | KIAA1671 | -0.0131286 |
| RPL11 | ribosomal protein L11 | -0.0131271 |
| FBXO17 | F-box protein 17 | -0.0130331 |
| MRPL42 | mitochondrial ribosomal protein L42 | -0.0129998 |
| SRSF2 | serine/arginine-rich splicing factor 2 | -0.0129733 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0129713 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0129397 |
| MSH5 | mutS homolog 5 | -0.0128668 |
| HDAC9 | histone deacetylase 9 | -0.0128154 |
| RAI14 | retinoic acid induced 14 | -0.0127729 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0126891 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.0126495 |
| IGF2 | insulin-like growth factor 2 | -0.0126347 |
| RPL39 | ribosomal protein L39 | -0.0125846 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0124767 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.0124729 |
| ZNF217 | zinc finger protein 217 | -0.0124359 |
| ATF4 | activating transcription factor 4 | -0.012424 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0124137 |
| VMA21 | VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) | -0.0123311 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0122841 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0122826 |
| OLA1 | Obg-like ATPase 1 | -0.0122724 |
