| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SAMD4A | sterile alpha motif domain containing 4A | 0.124617 |
| FNDC3B | fibronectin type III domain containing 3B | 0.104865 |
| MT2A | metallothionein 2A | 0.0947894 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.093833 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0928169 |
| SMAD3 | SMAD family member 3 | 0.0802944 |
| LAMC2 | laminin, gamma 2 | 0.0787836 |
| RAD51B | RAD51 paralog B | 0.0760201 |
| EFNA5 | ephrin-A5 | 0.0759141 |
| ASPH | aspartate beta-hydroxylase | 0.0679685 |
| CP | ceruloplasmin (ferroxidase) | 0.0658294 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0647118 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.061967 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0618504 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0597429 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0594504 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0591245 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.0555001 |
| RNF213 | ring finger protein 213 | 0.0552086 |
| TMSB4X | thymosin beta 4, X-linked | 0.0549852 |
| APOL1 | apolipoprotein L, 1 | 0.0541889 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0540899 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0527632 |
| AHNAK | AHNAK nucleoprotein | 0.0496899 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0490685 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0484121 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0482871 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0476151 |
| EGFR | epidermal growth factor receptor | 0.0471245 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0466679 |
| APP | amyloid beta (A4) precursor protein | 0.0465801 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0456754 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0450117 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0447921 |
| KIAA1217 | KIAA1217 | 0.0444845 |
| SEPTIN9 | septin 9 | 0.0441145 |
| MMP7 | matrix metallopeptidase 7 | 0.0436865 |
| LAMB3 | laminin, beta 3 | 0.043282 |
| PLEC | plectin | 0.0429341 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0426273 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.042292 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0406357 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0398039 |
| ITGA6 | integrin, alpha 6 | 0.0397075 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0391089 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0385891 |
| ANXA4 | annexin A4 | 0.0383647 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0383287 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0381032 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0377229 |
| TGM2 | transglutaminase 2 | 0.0375229 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0373603 |
| NRG3 | neuregulin 3 | 0.0369056 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0368263 |
| ATXN1 | ataxin 1 | 0.0367704 |
| PLAT | plasminogen activator, tissue | 0.0357631 |
| PARD3 | par-3 family cell polarity regulator | 0.0352861 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.035229 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0351974 |
| USP34 | ubiquitin specific peptidase 34 | 0.0347154 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0346045 |
| PRELID2 | PRELI domain containing 2 | 0.0343272 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0337763 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0336219 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.033307 |
| CMIP | c-Maf inducing protein | 0.03305 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.032799 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0322124 |
| CDCP1 | CUB domain containing protein 1 | 0.031646 |
| TMC5 | transmembrane channel-like 5 | 0.0306456 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0299407 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0297784 |
| MYOF | myoferlin | 0.0297285 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.029693 |
| NUMB | numb homolog (Drosophila) | 0.0296892 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0289058 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0288052 |
| ECE1 | endothelin converting enzyme 1 | 0.0287915 |
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | 0.0286476 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0283278 |
| LCN2 | lipocalin 2 | 0.028155 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0275031 |
| EXOC4 | exocyst complex component 4 | 0.0274691 |
| RPS8 | ribosomal protein S8 | 0.0274015 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0273551 |
| RPL19 | ribosomal protein L19 | 0.0272495 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0272056 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0271476 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0269006 |
| MT1E | metallothionein 1E | 0.0267839 |
| NRP1 | neuropilin 1 | 0.0267417 |
| AFAP1 | actin filament associated protein 1 | 0.0266701 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0264681 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0263862 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0263368 |
| BBX | bobby sox homolog (Drosophila) | 0.0262222 |
| BPTF | bromodomain PHD finger transcription factor | 0.0257152 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0256638 |
| OSMR | oncostatin M receptor | 0.0255121 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0251593 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.153149 |
| TSC22D2 | TSC22 domain family, member 2 | -0.127168 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.125704 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.117358 |
| SPAG9 | sperm associated antigen 9 | -0.0889144 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0746752 |
| HLA-A | major histocompatibility complex, class I, A | -0.0744585 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0714358 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0701015 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0667558 |
| NDRG1 | N-myc downstream regulated 1 | -0.0579359 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0575995 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0556147 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0554972 |
| PTMA | prothymosin, alpha | -0.0542378 |
| HMGA1 | high mobility group AT-hook 1 | -0.05329 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0527167 |
| RBM39 | RNA binding motif protein 39 | -0.0517832 |
| POTEF | POTE ankyrin domain family, member F | -0.0516267 |
| RAB7A | RAB7A, member RAS oncogene family | -0.048481 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0454816 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0454436 |
| RCOR1 | REST corepressor 1 | -0.0452021 |
| CCNL1 | cyclin L1 | -0.0446797 |
| S100A6 | S100 calcium binding protein A6 | -0.043829 |
| UBC | ubiquitin C | -0.0405349 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0367448 |
| LDHA | lactate dehydrogenase A | -0.0361312 |
| HELZ | helicase with zinc finger | -0.0359378 |
| PCBP2 | poly(rC) binding protein 2 | -0.0331318 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0327934 |
| TFG | TRK-fused gene | -0.0326137 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0325183 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.031895 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0318932 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0318411 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0315599 |
| ACTG1 | actin gamma 1 | -0.031445 |
| FTL | ferritin, light polypeptide | -0.0308861 |
| TJP1 | tight junction protein 1 | -0.0307887 |
| NPTN | neuroplastin | -0.0304354 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0303452 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0299879 |
| CLDN4 | claudin 4 | -0.0297226 |
| PAPOLA | poly(A) polymerase alpha | -0.0293495 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0288085 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0286697 |
| EGR1 | early growth response 1 | -0.0285205 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0281608 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0279866 |
| NUP58 | nucleoporin 58 | -0.0275874 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0274672 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.027217 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0270097 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0265187 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0264051 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0255142 |
| MCU | mitochondrial calcium uniporter | -0.0253405 |
| JUP | junction plakoglobin | -0.0250206 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0249726 |
| WASF2 | WAS protein family, member 2 | -0.0248061 |
| PLAU | plasminogen activator, urokinase | -0.0246152 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0245373 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0244631 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0244045 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0242206 |
| CDC73 | cell division cycle 73 | -0.0241679 |
| TAGLN2 | transgelin 2 | -0.0240742 |
| MUC1 | mucin 1, cell surface associated | -0.0238509 |
| IFRD1 | interferon-related developmental regulator 1 | -0.023636 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.023538 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0235374 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.023519 |
| ABI1 | abl-interactor 1 | -0.0234402 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0231763 |
| LMO7 | LIM domain 7 | -0.0230562 |
| NOP58 | NOP58 ribonucleoprotein | -0.0230244 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0229784 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0229663 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0229173 |
| SGMS2 | sphingomyelin synthase 2 | -0.0228011 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0226478 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0226466 |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 | -0.0225667 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0224052 |
| SIK3 | SIK family kinase 3 | -0.0223918 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0223452 |
| TUFT1 | tuftelin 1 | -0.0220487 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.022019 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -0.0219718 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0216405 |
| ZNF292 | zinc finger protein 292 | -0.0215839 |
| BRD2 | bromodomain containing 2 | -0.0212931 |
| RLF | rearranged L-myc fusion | -0.0208552 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0208318 |
| SEC24A | SEC24 family member A | -0.0207965 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0207175 |
| RNASEH2A | ribonuclease H2, subunit A | -0.0205694 |
| ZNF207 | zinc finger protein 207 | -0.0205368 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0203883 |
