| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.186702 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.123105 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.109791 |
| EXT1 | exostosin glycosyltransferase 1 | 0.102568 |
| TLE4 | transducin-like enhancer of split 4 | 0.100697 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0966489 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0852906 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0719284 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0679334 |
| FMN1 | formin 1 | 0.061926 |
| CENPF | centromere protein F, 350/400kDa | 0.0591116 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0569128 |
| FERMT2 | fermitin family member 2 | 0.0562718 |
| DPH6 | diphthamine biosynthesis 6 | 0.0550427 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0532904 |
| ACTG1 | actin gamma 1 | 0.0496793 |
| RPL3 | ribosomal protein L3 | 0.0480447 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0476717 |
| SEPTIN9 | septin 9 | 0.0468781 |
| GLCCI1 | glucocorticoid induced 1 | 0.0454091 |
| FAM107B | family with sequence similarity 107, member B | 0.0448148 |
| ACTN1 | actinin, alpha 1 | 0.0444553 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0442994 |
| APP | amyloid beta (A4) precursor protein | 0.0428778 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0427467 |
| THBS1 | thrombospondin 1 | 0.0422277 |
| TPM1 | tropomyosin 1 (alpha) | 0.0414885 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0412372 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0401124 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0386729 |
| DNMBP | dynamin binding protein | 0.0382214 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0381683 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0380944 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.038062 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0375131 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0370569 |
| FNBP1 | formin binding protein 1 | 0.0369509 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0365338 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0364586 |
| PRKCA | protein kinase C, alpha | 0.0355742 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0353221 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.035204 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0351355 |
| ENAH | enabled homolog (Drosophila) | 0.0344676 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0342679 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0338447 |
| AEBP2 | AE binding protein 2 | 0.0338151 |
| RPS6 | ribosomal protein S6 | 0.0334566 |
| VMP1 | vacuole membrane protein 1 | 0.0331897 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0326208 |
| SIK2 | salt-inducible kinase 2 | 0.0322855 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0322819 |
| DSTN | destrin (actin depolymerizing factor) | 0.0321815 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0316956 |
| AUTS2 | autism susceptibility candidate 2 | 0.0316707 |
| RPL23 | ribosomal protein L23 | 0.0314979 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0313666 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0309575 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.030807 |
| SMAD3 | SMAD family member 3 | 0.030746 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.030507 |
| MYO6 | myosin VI | 0.0304316 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0303685 |
| HOMER1 | homer scaffolding protein 1 | 0.0301233 |
| MEIS2 | Meis homeobox 2 | 0.0299285 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0296919 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.029247 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0291793 |
| TOP1 | topoisomerase (DNA) I | 0.0290199 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.028831 |
| ASPH | aspartate beta-hydroxylase | 0.0287076 |
| CRH | corticotropin releasing hormone | 0.0287044 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0285507 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0285151 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0281871 |
| AMOTL1 | angiomotin like 1 | 0.0281252 |
| NDRG1 | N-myc downstream regulated 1 | 0.0280427 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0280072 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0279204 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.027702 |
| GNAS | GNAS complex locus | 0.0276604 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0274508 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0274 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0273461 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0273225 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.027057 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0268897 |
| MYO1E | myosin IE | 0.0268376 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0267824 |
| RGS4 | regulator of G-protein signaling 4 | 0.0267662 |
| MED13 | mediator complex subunit 13 | 0.026758 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0264999 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0264855 |
| ACTN4 | actinin, alpha 4 | 0.0264102 |
| SSBP3 | single stranded DNA binding protein 3 | 0.026373 |
| IRS1 | insulin receptor substrate 1 | 0.0262943 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0258266 |
| RPL37 | ribosomal protein L37 | 0.0257161 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0256019 |
| GSE1 | Gse1 coiled-coil protein | 0.0255636 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.083508 |
| LSAMP | limbic system-associated membrane protein | -0.0754517 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0618725 |
| HIP1 | huntingtin interacting protein 1 | -0.043635 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0372919 |
| EGFR | epidermal growth factor receptor | -0.0351024 |
| COL1A1 | collagen, type I, alpha 1 | -0.0343583 |
| RAI14 | retinoic acid induced 14 | -0.0331351 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0320486 |
| NBEA | neurobeachin | -0.0319031 |
| ATXN10 | ataxin 10 | -0.030709 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0304042 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0290362 |
| CADM2 | cell adhesion molecule 2 | -0.0288523 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0275329 |
| SH3PXD2B | SH3 and PX domains 2B | -0.0256791 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0255712 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0240873 |
| RPL35A | ribosomal protein L35a | -0.0231752 |
| FRMD4A | FERM domain containing 4A | -0.0230924 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0229815 |
| COL3A1 | collagen, type III, alpha 1 | -0.0225434 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0218057 |
| ADAMTS19 | ADAM metallopeptidase with thrombospondin type 1 motif, 19 | -0.0217974 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0215916 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0212562 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.021193 |
| KIF5B | kinesin family member 5B | -0.0210292 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0209201 |
| PTEN | phosphatase and tensin homolog | -0.0208091 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0207004 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0204682 |
| YEATS2 | YEATS domain containing 2 | -0.0204088 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0203401 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0202894 |
| KLHL5 | kelch-like family member 5 | -0.0196698 |
| KCNIP4 | Kv channel interacting protein 4 | -0.0196692 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.019624 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0194719 |
| RPS2 | ribosomal protein S2 | -0.0192514 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0191182 |
| CALU | calumenin | -0.0189827 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0186492 |
| GPC5 | glypican 5 | -0.0185841 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | -0.0185436 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0184951 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0182938 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0182124 |
| EVL | Enah/Vasp-like | -0.0182089 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0180487 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0180429 |
| YLPM1 | YLP motif containing 1 | -0.0175406 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0170897 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | -0.0170032 |
| SENP7 | SUMO1/sentrin specific peptidase 7 | -0.0169511 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0167722 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0167679 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0167476 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0166914 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.016555 |
| NREP | neuronal regeneration related protein | -0.0164119 |
| ANGPT1 | angiopoietin 1 | -0.0163441 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.0161974 |
| HLA-A | major histocompatibility complex, class I, A | -0.0161547 |
| HMGA2 | high mobility group AT-hook 2 | -0.0161485 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0160257 |
| TMSB10 | thymosin beta 10 | -0.0159619 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0158943 |
| NVL | nuclear VCP-like | -0.0158925 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0158081 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0157694 |
| ZC3H7A | zinc finger CCCH-type containing 7A | -0.0156783 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0155828 |
| TBCK | TBC1 domain containing kinase | -0.0155538 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0154553 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0154004 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | -0.015397 |
| RBM27 | RNA binding motif protein 27 | -0.0152718 |
| NCK1 | NCK adaptor protein 1 | -0.0152601 |
| PRRX1 | paired related homeobox 1 | -0.0152559 |
| GOLGA4 | golgin A4 | -0.0152197 |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 | -0.0150041 |
| NKTR | natural killer cell triggering receptor | -0.0150021 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0148402 |
| ZNF292 | zinc finger protein 292 | -0.014767 |
| MEF2A | myocyte enhancer factor 2A | -0.0147554 |
| FGF13 | fibroblast growth factor 13 | -0.0147316 |
| SPAG16 | sperm associated antigen 16 | -0.0147084 |
| FTO | fat mass and obesity associated | -0.0146979 |
| EPHA3 | EPH receptor A3 | -0.0146518 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0144664 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.0143567 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0143449 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0143052 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | -0.0142897 |
| COPS2 | COP9 signalosome subunit 2 | -0.0142422 |
| ZNF814 | zinc finger protein 814 | -0.0142252 |
| RPLP1 | ribosomal protein, large, P1 | -0.0141918 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N | -0.0141321 |
| FOXK2 | forkhead box K2 | -0.0141021 |
