| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.14032 |
| RNF213 | ring finger protein 213 | 0.124234 |
| LCN2 | lipocalin 2 | 0.10914 |
| B2M | beta-2-microglobulin | 0.107871 |
| SMAD3 | SMAD family member 3 | 0.106335 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0951017 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0931577 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0921391 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0828839 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0786527 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0779972 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0778855 |
| ANXA2 | annexin A2 | 0.0752905 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0702665 |
| EFNB2 | ephrin-B2 | 0.068809 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0679158 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0671058 |
| VCL | vinculin | 0.0645289 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0630217 |
| PKM | pyruvate kinase, muscle | 0.0595065 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0584755 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0581366 |
| MYO1E | myosin IE | 0.0577639 |
| MSI2 | musashi RNA-binding protein 2 | 0.0575775 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.057133 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0568008 |
| AREG | amphiregulin | 0.0550269 |
| RUNX1 | runt-related transcription factor 1 | 0.0537657 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0536817 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0525755 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0522479 |
| PRKCA | protein kinase C, alpha | 0.0516725 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0511576 |
| SQSTM1 | sequestosome 1 | 0.0507215 |
| PERP | PERP, TP53 apoptosis effector | 0.0477713 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0474908 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0474449 |
| ASPH | aspartate beta-hydroxylase | 0.0459284 |
| HLA-B | major histocompatibility complex, class I, B | 0.0452535 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0452123 |
| INTS6 | integrator complex subunit 6 | 0.0451014 |
| ITGA6 | integrin, alpha 6 | 0.0450339 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0435091 |
| ACTG1 | actin gamma 1 | 0.0419256 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.041315 |
| SP100 | SP100 nuclear antigen | 0.0411561 |
| ETV6 | ets variant 6 | 0.0406621 |
| TRERF1 | transcriptional regulating factor 1 | 0.0390663 |
| MX2 | MX dynamin-like GTPase 2 | 0.0388763 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0386186 |
| TMC5 | transmembrane channel-like 5 | 0.0375556 |
| TJP1 | tight junction protein 1 | 0.0367041 |
| HKDC1 | hexokinase domain containing 1 | 0.0359244 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0357517 |
| LAMA4 | laminin, alpha 4 | 0.0356368 |
| ERBIN | erbb2 interacting protein | 0.0355524 |
| MED13 | mediator complex subunit 13 | 0.0354774 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0353301 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.035063 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.034991 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0346737 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0345027 |
| PLSCR2 | phospholipid scramblase 2 | 0.0339248 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0338225 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0331369 |
| EPHB2 | EPH receptor B2 | 0.0331293 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0330811 |
| ACTN4 | actinin, alpha 4 | 0.0327886 |
| CTBP2 | C-terminal binding protein 2 | 0.032761 |
| EZR | ezrin | 0.0327352 |
| MAP7 | microtubule-associated protein 7 | 0.0325801 |
| DSCAM | Down syndrome cell adhesion molecule | 0.032214 |
| ENO1 | enolase 1, (alpha) | 0.0322072 |
| MX1 | MX dynamin-like GTPase 1 | 0.0320204 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0318775 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0318724 |
| MUC13 | mucin 13, cell surface associated | 0.0317198 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0314985 |
| ATP11A | ATPase, class VI, type 11A | 0.0312641 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0309737 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0308601 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0308059 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0302187 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.029624 |
| FTL | ferritin, light polypeptide | 0.0293295 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0293032 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0292805 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0292678 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.028928 |
| MYO5B | myosin VB | 0.0289216 |
| KYNU | kynureninase | 0.0289003 |
| DST | dystonin | 0.0288999 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0286066 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0285977 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0284219 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0282609 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0282523 |
| EPCAM | epithelial cell adhesion molecule | 0.0282116 |
| PGK1 | phosphoglycerate kinase 1 | 0.0281907 |
| SEPTIN9 | septin 9 | 0.0279847 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0466227 |
| COG6 | component of oligomeric golgi complex 6 | -0.0251199 |
| GOLGB1 | golgin B1 | -0.0247712 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0200987 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0200191 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0193789 |
| PTEN | phosphatase and tensin homolog | -0.0182796 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0177149 |
| TMEM39A | transmembrane protein 39A | -0.0177123 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0173259 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0172111 |
| NDRG1 | N-myc downstream regulated 1 | -0.0160122 |
| COPA | coatomer protein complex, subunit alpha | -0.0159084 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0157893 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0154591 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0140988 |
| SEC24D | SEC24 family member D | -0.0137465 |
| CANX | calnexin | -0.0128767 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0123173 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0121724 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0117684 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0115556 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0114648 |
| TMEM263 | transmembrane protein 263 | -0.0113601 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | -0.0112108 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0110827 |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 | -0.0110277 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0108472 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0106264 |
| HM13 | histocompatibility (minor) 13 | -0.0102826 |
| RAB2A | RAB2A, member RAS oncogene family | -0.010178 |
| SRP54 | signal recognition particle 54kDa | -0.0101156 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.00998941 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.00998511 |
| SLC10A7 | solute carrier family 10, member 7 | -0.00987366 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.00986372 |
| TRAM1 | translocation associated membrane protein 1 | -0.00986012 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00981894 |
| LYZ | lysozyme | -0.00956289 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.00954096 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.00938969 |
| MTREX | Mtr4 exosome RNA helicase | -0.0093767 |
| LMAN1 | lectin, mannose-binding, 1 | -0.00936073 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.00929479 |
| SRBD1 | S1 RNA binding domain 1 | -0.00919271 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.00906897 |
| GOLGA4 | golgin A4 | -0.0090476 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.00891625 |
| KLHL24 | kelch-like family member 24 | -0.00886977 |
| TXNDC11 | thioredoxin domain containing 11 | -0.0088615 |
| FKBP9 | FK506 binding protein 9, 63 kDa | -0.0088294 |
| A1CF | APOBEC1 complementation factor | -0.00879857 |
| GRK3 | G protein-coupled receptor kinase 3 | -0.0087177 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.00871574 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.00865292 |
| WDR26 | WD repeat domain 26 | -0.00862999 |
| RAB6A | RAB6A, member RAS oncogene family | -0.00861482 |
| NUCB2 | nucleobindin 2 | -0.00859151 |
| CENPF | centromere protein F, 350/400kDa | -0.00858298 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.00855099 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.00848276 |
| COG3 | component of oligomeric golgi complex 3 | -0.00836659 |
| PGM3 | phosphoglucomutase 3 | -0.00833152 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.00822326 |
| ARF4 | ADP-ribosylation factor 4 | -0.00821646 |
| TFG | TRK-fused gene | -0.00816493 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | -0.00812426 |
| LYSMD3 | LysM, putative peptidoglycan-binding, domain containing 3 | -0.00811868 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.00811697 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.00789341 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.00788171 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.00787207 |
| GOSR2 | golgi SNAP receptor complex member 2 | -0.00787144 |
| INSIG1 | insulin induced gene 1 | -0.00786844 |
| SCARB1 | scavenger receptor class B, member 1 | -0.00785947 |
| TMF1 | TATA element modulatory factor 1 | -0.00783032 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.00780913 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.00772632 |
| MSMO1 | methylsterol monooxygenase 1 | -0.00767066 |
| USO1 | USO1 vesicle transport factor | -0.00766362 |
| SUCO | SUN domain containing ossification factor | -0.00764648 |
| ZNF652 | zinc finger protein 652 | -0.00764628 |
| ATOSA | atos homolog A | -0.00761214 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.00760873 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0075309 |
| SEC24A | SEC24 family member A | -0.00749364 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.00742582 |
| TMEM165 | transmembrane protein 165 | -0.00737287 |
| MCEE | methylmalonyl CoA epimerase | -0.00734795 |
| ZNF841 | zinc finger protein 841 | -0.00731133 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | -0.00729382 |
| USP3 | ubiquitin specific peptidase 3 | -0.00726409 |
| CALU | calumenin | -0.00724928 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.00723083 |
| JMY | junction mediating and regulatory protein, p53 cofactor | -0.00716225 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.00713617 |
| HELZ | helicase with zinc finger | -0.00710611 |
| ALPK1 | alpha-kinase 1 | -0.00710336 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | -0.00710291 |
| FOSL2 | FOS-like antigen 2 | -0.00709898 |
