| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.125152 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.121256 |
| ITGB8 | integrin, beta 8 | 0.120782 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.111216 |
| ACTG1 | actin gamma 1 | 0.0957539 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0851289 |
| SVIL | supervillin | 0.0764631 |
| SMAD3 | SMAD family member 3 | 0.0746479 |
| TXNRD1 | thioredoxin reductase 1 | 0.0724335 |
| ASPH | aspartate beta-hydroxylase | 0.0719442 |
| APP | amyloid beta (A4) precursor protein | 0.0707697 |
| ENO1 | enolase 1, (alpha) | 0.0701647 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0699331 |
| KRT7 | keratin 7, type II | 0.0680949 |
| PAX8 | paired box 8 | 0.0677257 |
| TMSB4X | thymosin beta 4, X-linked | 0.0645313 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.063846 |
| SNX9 | sorting nexin 9 | 0.0638001 |
| MKI67 | marker of proliferation Ki-67 | 0.0613822 |
| WWC1 | WW and C2 domain containing 1 | 0.0610967 |
| FLNA | filamin A, alpha | 0.0603424 |
| ANLN | anillin, actin binding protein | 0.0596437 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0589555 |
| SQSTM1 | sequestosome 1 | 0.0587203 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0577787 |
| ANXA1 | annexin A1 | 0.0573029 |
| VCL | vinculin | 0.0572877 |
| ACTN4 | actinin, alpha 4 | 0.0572207 |
| ECT2 | epithelial cell transforming 2 | 0.0567134 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0556986 |
| FLNB | filamin B, beta | 0.0546896 |
| H1-4 | H1.4 linker histone, cluster member | 0.0531745 |
| PKM | pyruvate kinase, muscle | 0.0517539 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0510139 |
| FTL | ferritin, light polypeptide | 0.0502242 |
| TJP1 | tight junction protein 1 | 0.0495124 |
| LDHA | lactate dehydrogenase A | 0.0495071 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0495013 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0489135 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0486088 |
| AHNAK | AHNAK nucleoprotein | 0.0482982 |
| ANXA2 | annexin A2 | 0.0482879 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0481919 |
| H1-0 | H1.0 linker histone | 0.0471752 |
| RUNX1 | runt-related transcription factor 1 | 0.0471526 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0469915 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0447031 |
| DSG2 | desmoglein 2 | 0.0443785 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0437808 |
| CCND1 | cyclin D1 | 0.0437151 |
| MACROD2 | MACRO domain containing 2 | 0.0436785 |
| SSH2 | slingshot protein phosphatase 2 | 0.0435424 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0434463 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0433261 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0431412 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0428874 |
| YBX1 | Y box binding protein 1 | 0.0418815 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.041688 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0411477 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0408112 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0401048 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0397314 |
| PLEC | plectin | 0.0390309 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0382317 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0382268 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0378274 |
| MYOF | myoferlin | 0.0377469 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0368516 |
| RPL19 | ribosomal protein L19 | 0.0367684 |
| RNF213 | ring finger protein 213 | 0.0366385 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.036573 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0365394 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.036266 |
| DPP4 | dipeptidyl-peptidase 4 | 0.035985 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0359125 |
| UBC | ubiquitin C | 0.0354086 |
| RHOA | ras homolog family member A | 0.0348075 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0347784 |
| EREG | epiregulin | 0.0343764 |
| CLTC | clathrin, heavy chain (Hc) | 0.0343526 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0342121 |
| B2M | beta-2-microglobulin | 0.0339961 |
| TKT | transketolase | 0.0339939 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0337266 |
| UPP1 | uridine phosphorylase 1 | 0.0336775 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0336555 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0333995 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0332552 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0332392 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0330682 |
| ATXN1 | ataxin 1 | 0.0329339 |
| TPM4 | tropomyosin 4 | 0.0328759 |
| CENPF | centromere protein F, 350/400kDa | 0.0322098 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0321622 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.031651 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0315978 |
| DSPP | dentin sialophosphoprotein | 0.0315634 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0315181 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0314688 |
| TUBB4B | tubulin, beta 4B class IVb | 0.031233 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.0966804 |
| TMSB10 | thymosin beta 10 | -0.0712003 |
| NDRG1 | N-myc downstream regulated 1 | -0.0547998 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0427752 |
| RPLP2 | ribosomal protein, large, P2 | -0.0243823 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0236189 |
| HMGA1 | high mobility group AT-hook 1 | -0.0220894 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0218763 |
| RPL31 | ribosomal protein L31 | -0.0216347 |
| RAD51B | RAD51 paralog B | -0.0202343 |
| RPS12 | ribosomal protein S12 | -0.0192276 |
| RPL9 | ribosomal protein L9 | -0.0189888 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0188628 |
| COX6C | cytochrome c oxidase subunit VIc | -0.0182939 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0182411 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0172735 |
| RPS21 | ribosomal protein S21 | -0.0162913 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.016032 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0159848 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0155325 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0145108 |
| FNIP1 | folliculin interacting protein 1 | -0.0136918 |
| TBCA | tubulin folding cofactor A | -0.0135551 |
| RBM25 | RNA binding motif protein 25 | -0.0135545 |
| PTMA | prothymosin, alpha | -0.0135181 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0135038 |
| ANK2 | ankyrin 2, neuronal | -0.0132485 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | -0.0131873 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0130508 |
| WDR43 | WD repeat domain 43 | -0.0130459 |
| TMX3 | thioredoxin-related transmembrane protein 3 | -0.0126875 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | -0.0122079 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0117112 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | -0.0117031 |
| PRKCE | protein kinase C, epsilon | -0.0114675 |
| TCAIM | T cell activation inhibitor, mitochondrial | -0.0113286 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0112365 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0112353 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0111305 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0108845 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0108414 |
| ENOSF1 | enolase superfamily member 1 | -0.0107451 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.010683 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0106487 |
| RPS17 | ribosomal protein S17 | -0.0105519 |
| PTEN | phosphatase and tensin homolog | -0.0104931 |
| RPL36AL | ribosomal protein L36a-like | -0.0104295 |
| RPS3 | ribosomal protein S3 | -0.0103954 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | -0.0103949 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | -0.0103608 |
| SEC24D | SEC24 family member D | -0.010304 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0102441 |
| BEX3 | brain expressed X-linked 3 | -0.0101544 |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 | -0.010109 |
| RAB10 | RAB10, member RAS oncogene family | -0.0100957 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | -0.00991238 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.00990843 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.00985632 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0098522 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 | -0.00976297 |
| NABP1 | nucleic acid binding protein 1 | -0.00973082 |
| THSD7A | thrombospondin, type I, domain containing 7A | -0.00968366 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | -0.00961178 |
| TAPBP | TAP binding protein (tapasin) | -0.00957699 |
| UBL5 | ubiquitin-like 5 | -0.00956996 |
| NCOR2 | nuclear receptor corepressor 2 | -0.00955032 |
| SURF4 | surfeit 4 | -0.00952997 |
| GPC5 | glypican 5 | -0.0094533 |
| MALT1 | MALT1 paracaspase | -0.00933638 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.00933298 |
| RPS19 | ribosomal protein S19 | -0.00923243 |
| TMEM165 | transmembrane protein 165 | -0.00917935 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial | -0.00917239 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.00913412 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0089189 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.00882762 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | -0.0087934 |
| ZNF248 | zinc finger protein 248 | -0.00876233 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0087242 |
| PGM3 | phosphoglucomutase 3 | -0.00866861 |
| RPS29 | ribosomal protein S29 | -0.00861902 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.00861862 |
| RPL21 | ribosomal protein L21 | -0.00859426 |
| INSIG2 | insulin induced gene 2 | -0.00856439 |
| UBL3 | ubiquitin-like 3 | -0.00856182 |
| DMGDH | dimethylglycine dehydrogenase | -0.00851019 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.00844196 |
| RPS14 | ribosomal protein S14 | -0.00844179 |
| NAV3 | neuron navigator 3 | -0.00842123 |
| DTWD2 | DTW domain containing 2 | -0.00841651 |
| VEGFA | vascular endothelial growth factor A | -0.00841283 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0084035 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.00837283 |
| RRBP1 | ribosome binding protein 1 | -0.00836743 |
| TMEM144 | transmembrane protein 144 | -0.00833041 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.00831969 |
| STC2 | stanniocalcin 2 | -0.00828928 |
| CENPK | centromere protein K | -0.00828408 |
| SRSF6 | serine/arginine-rich splicing factor 6 | -0.00826686 |
| ZNF841 | zinc finger protein 841 | -0.00823511 |
