| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lidocaine (hydrochloride)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.208593 |
| CD44 | CD44 molecule (Indian blood group) | 0.165403 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.148381 |
| HMGA2 | high mobility group AT-hook 2 | 0.144297 |
| COL5A1 | collagen, type V, alpha 1 | 0.141091 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.103565 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.101905 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0999933 |
| MT2A | metallothionein 2A | 0.0977978 |
| SEPTIN9 | septin 9 | 0.0900664 |
| NAV1 | neuron navigator 1 | 0.0895777 |
| ASPH | aspartate beta-hydroxylase | 0.0873336 |
| PLEC | plectin | 0.0857447 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0838184 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0824315 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.082221 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0813784 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0769956 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0753693 |
| AHNAK | AHNAK nucleoprotein | 0.0746945 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0746033 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.074435 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0740355 |
| MYO10 | myosin X | 0.05945 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0573494 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0566754 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0565527 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0545685 |
| FN1 | fibronectin 1 | 0.0540701 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.052881 |
| DST | dystonin | 0.052061 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.051991 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0518508 |
| STC1 | stanniocalcin 1 | 0.0512809 |
| COL6A1 | collagen, type VI, alpha 1 | 0.051135 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0502472 |
| CDCP1 | CUB domain containing protein 1 | 0.0485431 |
| CDH13 | cadherin 13 | 0.048065 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0476564 |
| ENO1 | enolase 1, (alpha) | 0.0467366 |
| GLIS3 | GLIS family zinc finger 3 | 0.0466308 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0455895 |
| LDHA | lactate dehydrogenase A | 0.0452411 |
| TUBB6 | tubulin, beta 6 class V | 0.0448767 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0434443 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0421727 |
| EGFR | epidermal growth factor receptor | 0.0420306 |
| RAI14 | retinoic acid induced 14 | 0.0420079 |
| SMAD3 | SMAD family member 3 | 0.0418763 |
| ANXA2 | annexin A2 | 0.0393356 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0393231 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0372787 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0371316 |
| VCL | vinculin | 0.0359565 |
| LOX | lysyl oxidase | 0.0358337 |
| FLNB | filamin B, beta | 0.0354139 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0354045 |
| LAMB3 | laminin, beta 3 | 0.0349174 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0348622 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0343349 |
| FLNA | filamin A, alpha | 0.0342157 |
| ACTG1 | actin gamma 1 | 0.0339077 |
| LOXL2 | lysyl oxidase-like 2 | 0.0331727 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0328272 |
| PCBP3 | poly(rC) binding protein 3 | 0.032597 |
| USP34 | ubiquitin specific peptidase 34 | 0.0319616 |
| OSMR | oncostatin M receptor | 0.0317323 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.03149 |
| ACTN1 | actinin, alpha 1 | 0.031389 |
| ATXN1 | ataxin 1 | 0.0313887 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0309854 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0309673 |
| CCND1 | cyclin D1 | 0.0303073 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0298265 |
| NAV2 | neuron navigator 2 | 0.0295157 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0292334 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0290274 |
| SMYD3 | SET and MYND domain containing 3 | 0.0288802 |
| FRMD4A | FERM domain containing 4A | 0.0285317 |
| DIAPH2 | diaphanous-related formin 2 | 0.0282065 |
| PRELID2 | PRELI domain containing 2 | 0.0278789 |
| RRM2 | ribonucleotide reductase M2 | 0.0278006 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0277861 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0277124 |
| PTK2 | protein tyrosine kinase 2 | 0.0276965 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0276271 |
| PRKCA | protein kinase C, alpha | 0.0269532 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0264226 |
| CCDC91 | coiled-coil domain containing 91 | 0.0263948 |
| BPTF | bromodomain PHD finger transcription factor | 0.0263444 |
| PKM | pyruvate kinase, muscle | 0.0261139 |
| CAVIN1 | caveolae associated protein 1 | 0.0259508 |
| TPM4 | tropomyosin 4 | 0.0259127 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0258966 |
| TPI1 | triosephosphate isomerase 1 | 0.0258178 |
| CLMP | CXADR-like membrane protein | 0.0257315 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0257061 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0256894 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0256808 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0256639 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | -0.0397394 |
| TMSB10 | thymosin beta 10 | -0.0391783 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0327652 |
| ZNF292 | zinc finger protein 292 | -0.0303756 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0290874 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0281768 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0276398 |
| TFG | TRK-fused gene | -0.0246212 |
| SPAG9 | sperm associated antigen 9 | -0.02434 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0224955 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.0220496 |
| RNF145 | ring finger protein 145 | -0.0219423 |
| RLF | rearranged L-myc fusion | -0.0215932 |
| USP3 | ubiquitin specific peptidase 3 | -0.0213889 |
| QKI | QKI, KH domain containing, RNA binding | -0.0213552 |
| CD109 | CD109 molecule | -0.0205294 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0196088 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0194437 |
| GOLGA4 | golgin A4 | -0.0188873 |
| ADM | adrenomedullin | -0.0186932 |
| FAM162A | family with sequence similarity 162, member A | -0.0183383 |
| NUP58 | nucleoporin 58 | -0.0181748 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0181124 |
| HELZ | helicase with zinc finger | -0.0179554 |
| NOP58 | NOP58 ribonucleoprotein | -0.0176015 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0173038 |
| JUN | jun proto-oncogene | -0.0172444 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0162096 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0160506 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0156446 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0151479 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | -0.0149499 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0148601 |
| RBM39 | RNA binding motif protein 39 | -0.0146721 |
| ZNF148 | zinc finger protein 148 | -0.0144521 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.014106 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0140592 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0139582 |
| SQSTM1 | sequestosome 1 | -0.0136757 |
| SRP54 | signal recognition particle 54kDa | -0.0136273 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0132735 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0132167 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0131758 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0131682 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0131612 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0131514 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0128523 |
| WDR43 | WD repeat domain 43 | -0.0128289 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0126913 |
| PCBP2 | poly(rC) binding protein 2 | -0.0126482 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0125217 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0124128 |
| GNAS | GNAS complex locus | -0.0121498 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -0.0120617 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0120291 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.011966 |
| ZNF207 | zinc finger protein 207 | -0.0116971 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0115413 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0113559 |
| MORF4L2 | mortality factor 4 like 2 | -0.0112768 |
| PER1 | period circadian clock 1 | -0.0111406 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0111275 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0109682 |
| HBP1 | HMG-box transcription factor 1 | -0.0108854 |
| CLINT1 | clathrin interactor 1 | -0.010851 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0107232 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0105954 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0104407 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0102852 |
| IGF2 | insulin-like growth factor 2 | -0.0102773 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0102312 |
| CCNL1 | cyclin L1 | -0.0102311 |
| CRY1 | cryptochrome circadian clock 1 | -0.0101242 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0101147 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.00987727 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.00984234 |
| YBX3 | Y box binding protein 3 | -0.00958043 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.00944093 |
| B2M | beta-2-microglobulin | -0.00940634 |
| FOXO3 | forkhead box O3 | -0.00934081 |
| YBX1 | Y box binding protein 1 | -0.00924873 |
| UBAP1 | ubiquitin associated protein 1 | -0.00920946 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | -0.00911843 |
| COLEC11 | collectin sub-family member 11 | -0.00911373 |
| PFN1 | profilin 1 | -0.00909942 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.00909286 |
| HDAC3 | histone deacetylase 3 | -0.00908092 |
| RYBP | RING1 and YY1 binding protein | -0.00906646 |
| SEC24A | SEC24 family member A | -0.00906603 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0090257 |
| RND3 | Rho family GTPase 3 | -0.00887597 |
| ANLN | anillin, actin binding protein | -0.00880614 |
| EWSR1 | EWS RNA-binding protein 1 | -0.00879042 |
| IER3 | immediate early response 3 | -0.00866529 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0086536 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.00862636 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.00858436 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00857796 |
| USP37 | ubiquitin specific peptidase 37 | -0.00850081 |
| FTL | ferritin, light polypeptide | -0.00846756 |
