| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.12214 |
| AHNAK | AHNAK nucleoprotein | 0.118348 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.107408 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0956772 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0894583 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0878233 |
| VCL | vinculin | 0.0836898 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0743628 |
| CD44 | CD44 molecule (Indian blood group) | 0.067973 |
| HMGA2 | high mobility group AT-hook 2 | 0.0665419 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0659625 |
| EFNA5 | ephrin-A5 | 0.0587785 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0586985 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0586178 |
| DST | dystonin | 0.0565998 |
| PLEC | plectin | 0.0557504 |
| NAV1 | neuron navigator 1 | 0.0556246 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0537827 |
| FLNA | filamin A, alpha | 0.0519944 |
| CAVIN1 | caveolae associated protein 1 | 0.0515848 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0501412 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0490197 |
| HDAC9 | histone deacetylase 9 | 0.0483279 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0474774 |
| USP34 | ubiquitin specific peptidase 34 | 0.0446149 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0445775 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0433662 |
| H1-4 | H1.4 linker histone, cluster member | 0.0427514 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0421174 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.041713 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.041373 |
| RPL4 | ribosomal protein L4 | 0.0403141 |
| PGK1 | phosphoglycerate kinase 1 | 0.0396473 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0375953 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0370474 |
| RPL38 | ribosomal protein L38 | 0.0363925 |
| PRKCE | protein kinase C, epsilon | 0.0360145 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0360104 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0348704 |
| HAS2 | hyaluronan synthase 2 | 0.0335806 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0327375 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0326831 |
| RPL6 | ribosomal protein L6 | 0.0320179 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0318015 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0316436 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0316147 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0313757 |
| ACTG1 | actin gamma 1 | 0.031364 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0311601 |
| RPL3 | ribosomal protein L3 | 0.0307737 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0307425 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0302881 |
| RPLP0 | ribosomal protein, large, P0 | 0.0302423 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0302348 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0302007 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0301362 |
| RPS24 | ribosomal protein S24 | 0.0298044 |
| RACK1 | receptor for activated C kinase 1 | 0.0297835 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0296919 |
| FRMD6 | FERM domain containing 6 | 0.0296352 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0290228 |
| KLF6 | Kruppel-like factor 6 | 0.0290014 |
| RAB1A | RAB1A, member RAS oncogene family | 0.028326 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.02776 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | 0.0274183 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0272505 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0269953 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0265712 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0261711 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.026144 |
| CFAP251 | cilia and flagella associated protein 251 | 0.0260839 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0260648 |
| CTTN | cortactin | 0.0258756 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0258107 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0257207 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0255127 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0252968 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0252881 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0252025 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0251715 |
| RNF213 | ring finger protein 213 | 0.0250422 |
| TOP1 | topoisomerase (DNA) I | 0.0249915 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0247842 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0242684 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0242068 |
| RPL37A | ribosomal protein L37a | 0.0240647 |
| NLK | nemo-like kinase | 0.0239889 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0239608 |
| MYO10 | myosin X | 0.0239338 |
| HLA-E | major histocompatibility complex, class I, E | 0.0238354 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.023747 |
| INHBA | inhibin, beta A | 0.0236553 |
| ENO1 | enolase 1, (alpha) | 0.023536 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.023391 |
| INTS6 | integrator complex subunit 6 | 0.0233604 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0233585 |
| AEBP2 | AE binding protein 2 | 0.0233541 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.0232292 |
| RPL37 | ribosomal protein L37 | 0.0231724 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0231625 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.131049 |
| POTEF | POTE ankyrin domain family, member F | -0.11376 |
| MMP12 | matrix metallopeptidase 12 | -0.100105 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0834752 |
| RPS6 | ribosomal protein S6 | -0.0731726 |
| PTMA | prothymosin, alpha | -0.0688709 |
| HMGA1 | high mobility group AT-hook 1 | -0.0656902 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.060453 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.057758 |
| NDRG1 | N-myc downstream regulated 1 | -0.0574644 |
| VIM | vimentin | -0.0565642 |
| PFN1 | profilin 1 | -0.0445193 |
| RPS19 | ribosomal protein S19 | -0.0444151 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.043767 |
| RPL21 | ribosomal protein L21 | -0.0432814 |
| EGR1 | early growth response 1 | -0.0431039 |
| MSN | moesin | -0.041953 |
| PCBP2 | poly(rC) binding protein 2 | -0.0393647 |
| RPL35A | ribosomal protein L35a | -0.0359907 |
| DTNA | dystrobrevin, alpha | -0.0359268 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0354112 |
| RPLP2 | ribosomal protein, large, P2 | -0.0339576 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0321349 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0317263 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0315123 |
| RNF145 | ring finger protein 145 | -0.0308293 |
| FTL | ferritin, light polypeptide | -0.0307819 |
| RPS23 | ribosomal protein S23 | -0.0305049 |
| NUP58 | nucleoporin 58 | -0.030404 |
| GPC6 | glypican 6 | -0.0303504 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0302366 |
| ZNF292 | zinc finger protein 292 | -0.0300121 |
| FOSL1 | FOS-like antigen 1 | -0.0290655 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0286503 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.028414 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0278763 |
| FNDC3B | fibronectin type III domain containing 3B | -0.027653 |
| NRP2 | neuropilin 2 | -0.0271838 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0265231 |
| TXNIP | thioredoxin interacting protein | -0.0262105 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0260169 |
| PTK2 | protein tyrosine kinase 2 | -0.0247696 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.024618 |
| RPS14 | ribosomal protein S14 | -0.0245839 |
| RPS16 | ribosomal protein S16 | -0.0238621 |
| YBX1 | Y box binding protein 1 | -0.0237842 |
| SBF2 | SET binding factor 2 | -0.0234794 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0226142 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0225628 |
| MSR1 | macrophage scavenger receptor 1 | -0.0224788 |
| TFG | TRK-fused gene | -0.0223839 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0223696 |
| MT2A | metallothionein 2A | -0.0219275 |
| RPL36 | ribosomal protein L36 | -0.0219235 |
| TMPRSS15 | transmembrane protease, serine 15 | -0.0218103 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0217384 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0216204 |
| RDX | radixin | -0.0212604 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0212493 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0209113 |
| PKM | pyruvate kinase, muscle | -0.0207898 |
| RPL8 | ribosomal protein L8 | -0.020781 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0206271 |
| PTMS | parathymosin | -0.0202744 |
| ATP11B | ATPase, class VI, type 11B | -0.0200396 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0193293 |
| DEK | DEK proto-oncogene | -0.0192394 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0191938 |
| TAOK3 | TAO kinase 3 | -0.019052 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0190187 |
| AXL | AXL receptor tyrosine kinase | -0.0189081 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.018825 |
| PARD3 | par-3 family cell polarity regulator | -0.0186944 |
| RPS11 | ribosomal protein S11 | -0.0186808 |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 | -0.01856 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0185017 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0182485 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0182189 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0182042 |
| MYADM | myeloid-associated differentiation marker | -0.0180525 |
| HELZ | helicase with zinc finger | -0.0180121 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0180006 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0176937 |
| RPS21 | ribosomal protein S21 | -0.0176517 |
| DNER | delta/notch-like EGF repeat containing | -0.0175566 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0174423 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0174102 |
| RPS25 | ribosomal protein S25 | -0.0173217 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0172538 |
| QKI | QKI, KH domain containing, RNA binding | -0.0172491 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.017212 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.017069 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0168794 |
| CDK19 | cyclin-dependent kinase 19 | -0.0168723 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0167359 |
| CSRP1 | cysteine and glycine-rich protein 1 | -0.0166037 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | -0.0165806 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0165709 |
| KMT2D | lysine (K)-specific methyltransferase 2D | -0.0165273 |
| RYBP | RING1 and YY1 binding protein | -0.0163186 |
