| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.154452 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.148434 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.140745 |
| FAT1 | FAT atypical cadherin 1 | 0.133004 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.115031 |
| MYO1E | myosin IE | 0.092026 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0853279 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0833997 |
| ACTG1 | actin gamma 1 | 0.0827965 |
| AHNAK | AHNAK nucleoprotein | 0.0818376 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0785758 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0778329 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0733015 |
| ONECUT3 | one cut homeobox 3 | 0.0712444 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0674712 |
| KRT8 | keratin 8, type II | 0.0647375 |
| VCL | vinculin | 0.0641712 |
| FHIT | fragile histidine triad | 0.0624317 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0611432 |
| H1-4 | H1.4 linker histone, cluster member | 0.0597783 |
| KRT18 | keratin 18, type I | 0.0590038 |
| EGFR | epidermal growth factor receptor | 0.0585586 |
| MUC13 | mucin 13, cell surface associated | 0.0570149 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0532276 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0531858 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0522596 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0516427 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0505373 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0475491 |
| H1-0 | H1.0 linker histone | 0.0474772 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0472802 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0469643 |
| PLEC | plectin | 0.0461992 |
| LMO7 | LIM domain 7 | 0.0456877 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0453693 |
| SMYD3 | SET and MYND domain containing 3 | 0.0452817 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0448171 |
| ASPH | aspartate beta-hydroxylase | 0.0442708 |
| DSPP | dentin sialophosphoprotein | 0.0428772 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0423804 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0413497 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0411465 |
| MYO5B | myosin VB | 0.0400365 |
| RPL3 | ribosomal protein L3 | 0.039035 |
| CD44 | CD44 molecule (Indian blood group) | 0.0386789 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0382116 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0380512 |
| SVIL | supervillin | 0.0378052 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0371295 |
| APP | amyloid beta (A4) precursor protein | 0.0370637 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0362488 |
| ACTN4 | actinin, alpha 4 | 0.0361032 |
| PKM | pyruvate kinase, muscle | 0.035994 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0359381 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0353475 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.03507 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0346994 |
| NRXN3 | neurexin 3 | 0.0346829 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0343391 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.034325 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0342735 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0341222 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0339067 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0337739 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.032837 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0327196 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0327136 |
| MED13 | mediator complex subunit 13 | 0.0322284 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0320216 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0318587 |
| RPS8 | ribosomal protein S8 | 0.0317972 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0317453 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0314254 |
| SEPTIN9 | septin 9 | 0.0312594 |
| ABR | active BCR-related | 0.0311707 |
| PDZD8 | PDZ domain containing 8 | 0.0308937 |
| RPS12 | ribosomal protein S12 | 0.0308476 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0307533 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0305326 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0303846 |
| H1-2 | H1.2 linker histone, cluster member | 0.0303565 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.030037 |
| CADPS | Ca++-dependent secretion activator | 0.0298649 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0298447 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.0298006 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0296263 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0290668 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0290242 |
| RPLP1 | ribosomal protein, large, P1 | 0.0286723 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.028308 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0282893 |
| FLNA | filamin A, alpha | 0.0281409 |
| SQSTM1 | sequestosome 1 | 0.0279935 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0278077 |
| CTBP2 | C-terminal binding protein 2 | 0.027763 |
| ECT2 | epithelial cell transforming 2 | 0.0273214 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0273145 |
| SMAD3 | SMAD family member 3 | 0.0273141 |
| SMAD2 | SMAD family member 2 | 0.0270259 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0268332 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.208967 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0979013 |
| NDRG1 | N-myc downstream regulated 1 | -0.0876543 |
| PTMA | prothymosin, alpha | -0.0782609 |
| TMSB10 | thymosin beta 10 | -0.0774932 |
| GOLGA4 | golgin A4 | -0.0729293 |
| NPSR1 | neuropeptide S receptor 1 | -0.0581037 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0559216 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0538801 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0536282 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0524821 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0515898 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0495373 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.048261 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0473795 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0461499 |
| CALB1 | calbindin 1, 28kDa | -0.045844 |
| TNS4 | tensin 4 | -0.044561 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0444848 |
| FAM13A | family with sequence similarity 13, member A | -0.0405022 |
| RNF145 | ring finger protein 145 | -0.0405003 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0401312 |
| ITGB4 | integrin, beta 4 | -0.0386323 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0381839 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0345784 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0336745 |
| HMGA1 | high mobility group AT-hook 1 | -0.0336713 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0318367 |
| MUC17 | mucin 17, cell surface associated | -0.0317116 |
| PTEN | phosphatase and tensin homolog | -0.0314087 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0313508 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.030733 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0304892 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0304506 |
| ANXA2 | annexin A2 | -0.0300178 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0299911 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.029343 |
| EXOC1 | exocyst complex component 1 | -0.0291985 |
| VEGFA | vascular endothelial growth factor A | -0.0290534 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0289359 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0288019 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0282587 |
| CCNY | cyclin Y | -0.0280856 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0277462 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0276012 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0273923 |
| ZNF292 | zinc finger protein 292 | -0.0271715 |
| GPHN | gephyrin | -0.0271398 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0269225 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0260853 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0255706 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0255155 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0254748 |
| SBF2 | SET binding factor 2 | -0.0248563 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0246323 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0241716 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0240212 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0236303 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0232068 |
| INSIG1 | insulin induced gene 1 | -0.0229469 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.022676 |
| TMF1 | TATA element modulatory factor 1 | -0.0225136 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.02244 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0224205 |
| PCBP2 | poly(rC) binding protein 2 | -0.0223033 |
| WASF2 | WAS protein family, member 2 | -0.022291 |
| USP3 | ubiquitin specific peptidase 3 | -0.0221141 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0219294 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0219282 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0218855 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0218369 |
| COG5 | component of oligomeric golgi complex 5 | -0.0217509 |
| NBAS | neuroblastoma amplified sequence | -0.0212931 |
| SETD5 | SET domain containing 5 | -0.0211466 |
| THOC2 | THO complex 2 | -0.0210916 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0210828 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0209772 |
| METTL15 | methyltransferase like 15 | -0.0208511 |
| ARF4 | ADP-ribosylation factor 4 | -0.0205085 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.0204537 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0204073 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.0202553 |
| PHKB | phosphorylase kinase, beta | -0.0201525 |
| TMEM41B | transmembrane protein 41B | -0.0201345 |
| SRP54 | signal recognition particle 54kDa | -0.0199851 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0199386 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0199261 |
| COPA | coatomer protein complex, subunit alpha | -0.0198753 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0197428 |
| FERMT1 | fermitin family member 1 | -0.0196664 |
| TMEM165 | transmembrane protein 165 | -0.0195655 |
| PRSS3 | protease, serine, 3 | -0.0194723 |
| MED13L | mediator complex subunit 13-like | -0.0193602 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0191963 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0191916 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0191905 |
| FNBP1L | formin binding protein 1-like | -0.0190246 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0189836 |
| SCFD1 | sec1 family domain containing 1 | -0.0189158 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0188228 |
