| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0962947 |
| DST | dystonin | 0.0948409 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0824262 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0696123 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0688832 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0646064 |
| FMNL2 | formin-like 2 | 0.0643888 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0635702 |
| RUNX1 | runt-related transcription factor 1 | 0.0631429 |
| CAPRIN2 | caprin family member 2 | 0.0602181 |
| EZR | ezrin | 0.0567168 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0516194 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0507407 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0506746 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0490436 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.047774 |
| PLEC | plectin | 0.0469292 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0435324 |
| RCOR1 | REST corepressor 1 | 0.0421106 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0419395 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0403542 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0401693 |
| RPL3 | ribosomal protein L3 | 0.0400475 |
| USP34 | ubiquitin specific peptidase 34 | 0.0384936 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0383667 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.037267 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0368056 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.036621 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0362387 |
| MYOF | myoferlin | 0.0354507 |
| MB21D2 | Mab-21 domain containing 2 | 0.0338684 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0333365 |
| SMAD3 | SMAD family member 3 | 0.0322435 |
| CMIP | c-Maf inducing protein | 0.0321452 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0318277 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0311963 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0311766 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0299565 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0296265 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0293948 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0291722 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0287531 |
| RPS18 | ribosomal protein S18 | 0.0287178 |
| PLK2 | polo-like kinase 2 | 0.0273734 |
| HOMER1 | homer scaffolding protein 1 | 0.026739 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0262793 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0259104 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0259074 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0258792 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0252701 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0249262 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0246897 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0241651 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0240556 |
| SPAG9 | sperm associated antigen 9 | 0.0235854 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0235848 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0235097 |
| KRT18 | keratin 18, type I | 0.023423 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0232803 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0230399 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0229396 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0225416 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0224429 |
| NAV2 | neuron navigator 2 | 0.0224361 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0224114 |
| TOP1 | topoisomerase (DNA) I | 0.0223261 |
| PYGB | phosphorylase, glycogen; brain | 0.0221827 |
| LYST | lysosomal trafficking regulator | 0.0219346 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0218028 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0217192 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0216968 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0214764 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0214614 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0212564 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0209736 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0207646 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0207297 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0206877 |
| USP11 | ubiquitin specific peptidase 11 | 0.020589 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0205289 |
| LOXL2 | lysyl oxidase-like 2 | 0.020428 |
| DNER | delta/notch-like EGF repeat containing | 0.0204037 |
| MOK | MOK protein kinase | 0.0201491 |
| HDLBP | high density lipoprotein binding protein | 0.0199895 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0199642 |
| AHNAK | AHNAK nucleoprotein | 0.0198661 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0196789 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0196719 |
| RGS4 | regulator of G-protein signaling 4 | 0.019603 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0195734 |
| AREG | amphiregulin | 0.019421 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0194133 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0193887 |
| BRD2 | bromodomain containing 2 | 0.0191174 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0191163 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0189777 |
| VEGFC | vascular endothelial growth factor C | 0.0187428 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0184841 |
| INTS6 | integrator complex subunit 6 | 0.0184835 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0182052 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.115129 |
| PTMA | prothymosin, alpha | -0.109333 |
| TMSB10 | thymosin beta 10 | -0.0764585 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0668915 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0609539 |
| HLA-B | major histocompatibility complex, class I, B | -0.0573852 |
| CANX | calnexin | -0.0502328 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0472083 |
| RIGI | RNA sensor RIG-I | -0.0471772 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0381818 |
| RPL35A | ribosomal protein L35a | -0.0362195 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0360675 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0358585 |
| UBC | ubiquitin C | -0.0357781 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0357191 |
| RPL12 | ribosomal protein L12 | -0.0336623 |
| RPS27A | ribosomal protein S27a | -0.0336487 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0327537 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.031234 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.031031 |
| HMGA1 | high mobility group AT-hook 1 | -0.0306213 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.030427 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0297249 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0296889 |
| FTL | ferritin, light polypeptide | -0.0290978 |
| MT1E | metallothionein 1E | -0.0289235 |
| ENO1 | enolase 1, (alpha) | -0.0265685 |
| B2M | beta-2-microglobulin | -0.0262643 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0255279 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0254775 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0250518 |
| PMP22 | peripheral myelin protein 22 | -0.0242221 |
| TP63 | tumor protein p63 | -0.0235777 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.02338 |
| RPS8 | ribosomal protein S8 | -0.0230472 |
| DPH6 | diphthamine biosynthesis 6 | -0.0229912 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.02278 |
| SP100 | SP100 nuclear antigen | -0.0219072 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0210798 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0206569 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0205269 |
| RPL26 | ribosomal protein L26 | -0.0204059 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0204026 |
| LDHA | lactate dehydrogenase A | -0.0202455 |
| RACK1 | receptor for activated C kinase 1 | -0.0201569 |
| CALR | calreticulin | -0.0198669 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0196262 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0195443 |
| S100A6 | S100 calcium binding protein A6 | -0.0194656 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0181279 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0181263 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0178318 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0177351 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0175847 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0174974 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.017491 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0171376 |
| RPS21 | ribosomal protein S21 | -0.0168689 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0168433 |
| HLA-A | major histocompatibility complex, class I, A | -0.0167171 |
| RPL34 | ribosomal protein L34 | -0.0166303 |
| RPL9 | ribosomal protein L9 | -0.0165274 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0164645 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0163857 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0163237 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0162661 |
| HLA-E | major histocompatibility complex, class I, E | -0.016208 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0159335 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | -0.0156655 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.0154042 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0153781 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0152379 |
| RPS28 | ribosomal protein S28 | -0.0152273 |
| CFDP1 | craniofacial development protein 1 | -0.0150906 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0150753 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0150538 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0149911 |
| RPS14 | ribosomal protein S14 | -0.0149193 |
| RPL36A | ribosomal protein L36a | -0.0146972 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0146735 |
| CCDC91 | coiled-coil domain containing 91 | -0.0145907 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0144615 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0143953 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0143892 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0142835 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0141855 |
| VPS35 | vacuolar protein sorting 35 homolog (S. cerevisiae) | -0.0140428 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0139413 |
| PGK1 | phosphoglycerate kinase 1 | -0.0138106 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.013549 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0134202 |
| WDR43 | WD repeat domain 43 | -0.0132992 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0132132 |
| GOLGA4 | golgin A4 | -0.0131512 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0129858 |
| WDR45B | WD repeat domain 45B | -0.0129164 |
| THOC2 | THO complex 2 | -0.0127634 |
| XPO1 | exportin 1 | -0.0127261 |
| S100A9 | S100 calcium binding protein A9 | -0.0126415 |
| SNX6 | sorting nexin 6 | -0.0126238 |
