| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | 0.131042 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.110297 |
| LOX | lysyl oxidase | 0.104486 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0890318 |
| SMAD3 | SMAD family member 3 | 0.0809027 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.079367 |
| HMGA2 | high mobility group AT-hook 2 | 0.0764659 |
| VIM | vimentin | 0.0740441 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0722454 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0710032 |
| STC1 | stanniocalcin 1 | 0.0703432 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0695004 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.065877 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0639733 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0628216 |
| FN1 | fibronectin 1 | 0.0626124 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0606008 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0600476 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0551991 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0549667 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.051943 |
| NTN4 | netrin 4 | 0.0517239 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0508225 |
| CA12 | carbonic anhydrase XII | 0.0502907 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0497828 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0478971 |
| KYNU | kynureninase | 0.047017 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0462928 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0460089 |
| LDHA | lactate dehydrogenase A | 0.0447918 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0442271 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0437861 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0435793 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0434874 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0420514 |
| OSMR | oncostatin M receptor | 0.0416171 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0398533 |
| ATXN1 | ataxin 1 | 0.0397028 |
| ECE1 | endothelin converting enzyme 1 | 0.0396267 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0395671 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0394255 |
| PFKP | phosphofructokinase, platelet | 0.0385787 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0378156 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0375327 |
| BPTF | bromodomain PHD finger transcription factor | 0.0361773 |
| PKM | pyruvate kinase, muscle | 0.0359924 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0356657 |
| IL6ST | interleukin 6 signal transducer | 0.0352095 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0350623 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.034909 |
| TGM2 | transglutaminase 2 | 0.0334448 |
| SYNJ2 | synaptojanin 2 | 0.0330083 |
| DST | dystonin | 0.0329514 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0328459 |
| LOXL2 | lysyl oxidase-like 2 | 0.0328244 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0328002 |
| UBC | ubiquitin C | 0.0323064 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0322201 |
| ANXA2 | annexin A2 | 0.0318793 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0317796 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0317503 |
| HIP1 | huntingtin interacting protein 1 | 0.0316862 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.031221 |
| GLCCI1 | glucocorticoid induced 1 | 0.0311019 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0306128 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0305055 |
| RAI14 | retinoic acid induced 14 | 0.0304169 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0300106 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0298618 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0297978 |
| FLNB | filamin B, beta | 0.0292781 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0284662 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0282797 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0281558 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0279487 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0276586 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0275179 |
| CDCP1 | CUB domain containing protein 1 | 0.0275162 |
| SEPTIN9 | septin 9 | 0.0272528 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0267675 |
| EGFR | epidermal growth factor receptor | 0.0267628 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.026459 |
| USP34 | ubiquitin specific peptidase 34 | 0.0264541 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0262891 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0258725 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0251345 |
| ARFGEF3 | ARFGEF family member 3 | 0.0249003 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0248607 |
| MX2 | MX dynamin-like GTPase 2 | 0.0248518 |
| PGK1 | phosphoglycerate kinase 1 | 0.0247955 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0246433 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0246148 |
| SVIL | supervillin | 0.024498 |
| SP100 | SP100 nuclear antigen | 0.0243434 |
| MEF2A | myocyte enhancer factor 2A | 0.0242652 |
| RPL3 | ribosomal protein L3 | 0.024241 |
| ANO6 | anoctamin 6 | 0.0242132 |
| TMSB4X | thymosin beta 4, X-linked | 0.024172 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0241154 |
| TPI1 | triosephosphate isomerase 1 | 0.0239311 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.152828 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0686378 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.042822 |
| EGR1 | early growth response 1 | -0.0416766 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0372195 |
| VEGFA | vascular endothelial growth factor A | -0.0371488 |
| HMGA1 | high mobility group AT-hook 1 | -0.034666 |
| RPS19 | ribosomal protein S19 | -0.0343253 |
| NDRG1 | N-myc downstream regulated 1 | -0.034275 |
| PTMA | prothymosin, alpha | -0.0327581 |
| PCBP2 | poly(rC) binding protein 2 | -0.0318883 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0317135 |
| GOLGA4 | golgin A4 | -0.0313789 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0301371 |
| RPS21 | ribosomal protein S21 | -0.029882 |
| RPLP2 | ribosomal protein, large, P2 | -0.0290669 |
| SIK3 | SIK family kinase 3 | -0.0290658 |
| RPL36 | ribosomal protein L36 | -0.0289978 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0268669 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | -0.0258103 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0254433 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0253503 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0250294 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0242206 |
| EFNA5 | ephrin-A5 | -0.023254 |
| ARF4 | ADP-ribosylation factor 4 | -0.0231814 |
| RBM39 | RNA binding motif protein 39 | -0.023114 |
| HLA-B | major histocompatibility complex, class I, B | -0.0225245 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0222515 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.021106 |
| RSF1 | remodeling and spacing factor 1 | -0.020778 |
| RPL34 | ribosomal protein L34 | -0.0197408 |
| THOC2 | THO complex 2 | -0.0193605 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0191386 |
| MIDN | midnolin | -0.0188982 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0186011 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0185666 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0184863 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0184854 |
| RPS29 | ribosomal protein S29 | -0.0184353 |
| RPL35A | ribosomal protein L35a | -0.0182008 |
| MT2A | metallothionein 2A | -0.0181213 |
| MORF4L2 | mortality factor 4 like 2 | -0.0180648 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0180523 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0179575 |
| CLMP | CXADR-like membrane protein | -0.0176665 |
| COL7A1 | collagen, type VII, alpha 1 | -0.017624 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0172809 |
| WASF2 | WAS protein family, member 2 | -0.0165559 |
| LRRC49 | leucine rich repeat containing 49 | -0.0165534 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0164872 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.0164661 |
| LRRC8C | leucine rich repeat containing 8 family, member C | -0.0163598 |
| FAM193A | family with sequence similarity 193, member A | -0.0159798 |
| TMEM165 | transmembrane protein 165 | -0.0159527 |
| KIF1B | kinesin family member 1B | -0.0157731 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.0155976 |
| MTSS1 | metastasis suppressor 1 | -0.0155405 |
| TMEM263 | transmembrane protein 263 | -0.0154594 |
| RPS23 | ribosomal protein S23 | -0.0151971 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0151342 |
| NLRP1 | NLR family, pyrin domain containing 1 | -0.0148649 |
| RAI1 | retinoic acid induced 1 | -0.0148516 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0146215 |
| NUCB2 | nucleobindin 2 | -0.0146018 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.014591 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0145691 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0145627 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0141834 |
| LINC02798 | long intergenic non-protein coding RNA 2798 | -0.0141101 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0141046 |
| RPS6 | ribosomal protein S6 | -0.0140793 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0139437 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0139333 |
| MMP24OS | MMP24 opposite strand | -0.0138059 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0137832 |
| FTL | ferritin, light polypeptide | -0.0137816 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.0137144 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0135996 |
| S100A9 | S100 calcium binding protein A9 | -0.0135917 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0133526 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0132455 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0132147 |
| ZNF407 | zinc finger protein 407 | -0.0131346 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.013088 |
| MYADM | myeloid-associated differentiation marker | -0.0130663 |
| ATP5MC2 | ATP synthase membrane subunit c locus 2 | -0.012855 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | -0.0127824 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0127553 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0126136 |
| METTL15 | methyltransferase like 15 | -0.0125962 |
| SEM1 | SEM1 26S proteasome subunit | -0.0123615 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0122799 |
| OXSR1 | oxidative stress responsive 1 | -0.0122776 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0122139 |
| RPL23 | ribosomal protein L23 | -0.0122121 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0120878 |
| COMMD1 | copper metabolism (Murr1) domain containing 1 | -0.0120334 |
| ZNF438 | zinc finger protein 438 | -0.0119663 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.011919 |
