| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.19916 |
| MYO1E | myosin IE | 0.160584 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.130679 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.114946 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.110532 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.10619 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.10429 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0935352 |
| EFNA5 | ephrin-A5 | 0.0888554 |
| AHNAK | AHNAK nucleoprotein | 0.0839451 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0802755 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0785821 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0772137 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0763038 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0737688 |
| LAMC2 | laminin, gamma 2 | 0.072695 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.072278 |
| S100A9 | S100 calcium binding protein A9 | 0.0711738 |
| LOC112694756 | uncharaterized LOC112694756 | 0.069822 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0694377 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0671678 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0652784 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0646036 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0629615 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0613147 |
| DSPP | dentin sialophosphoprotein | 0.0588404 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0579616 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0572472 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0560108 |
| EZR | ezrin | 0.0558378 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0557109 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0541596 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0529454 |
| RPS6 | ribosomal protein S6 | 0.0524102 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0522238 |
| RPS3 | ribosomal protein S3 | 0.0504751 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0499828 |
| SVIL | supervillin | 0.0496527 |
| FLNB | filamin B, beta | 0.0496205 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0494206 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0493852 |
| EGFR | epidermal growth factor receptor | 0.0493224 |
| MUC16 | mucin 16, cell surface associated | 0.0491329 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0485957 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0483362 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0479266 |
| MUC13 | mucin 13, cell surface associated | 0.0475329 |
| PERP | PERP, TP53 apoptosis effector | 0.0471986 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0467242 |
| ABHD17C | abhydrolase domain containing 17C | 0.0463296 |
| LAMA4 | laminin, alpha 4 | 0.0462749 |
| WWC1 | WW and C2 domain containing 1 | 0.0453062 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0449687 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0449251 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0447835 |
| MYOF | myoferlin | 0.0446819 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0439033 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0434938 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0431476 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0422881 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0421871 |
| RPL23 | ribosomal protein L23 | 0.0420908 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0418462 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0412195 |
| ATXN1 | ataxin 1 | 0.0411058 |
| RPLP1 | ribosomal protein, large, P1 | 0.0410713 |
| CMIP | c-Maf inducing protein | 0.0405581 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0404588 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0397238 |
| RPS12 | ribosomal protein S12 | 0.0396953 |
| NPTN | neuroplastin | 0.0389955 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0388609 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0381294 |
| TOP1 | topoisomerase (DNA) I | 0.038089 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0380777 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0377778 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0376988 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0376482 |
| LAMB3 | laminin, beta 3 | 0.0372619 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0366955 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0364216 |
| USP6NL | USP6 N-terminal like | 0.0363444 |
| ATOSA | atos homolog A | 0.0362559 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0359121 |
| ANXA1 | annexin A1 | 0.0358551 |
| SMAD3 | SMAD family member 3 | 0.0357827 |
| NABP1 | nucleic acid binding protein 1 | 0.0352219 |
| KRT17 | keratin 17, type I | 0.0347767 |
| PTK2 | protein tyrosine kinase 2 | 0.0343476 |
| H3-3B | H3.3 histone B | 0.0338929 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0336605 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0335135 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0329335 |
| NEBL | nebulette | 0.0327433 |
| DUSP5 | dual specificity phosphatase 5 | 0.0324345 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.032204 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0312491 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0310731 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.030422 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.0302308 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPAG9 | sperm associated antigen 9 | -0.0910074 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0805023 |
| GPC6 | glypican 6 | -0.0791783 |
| RIGI | RNA sensor RIG-I | -0.0790565 |
| LSAMP | limbic system-associated membrane protein | -0.075785 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0751872 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0744803 |
| RNF145 | ring finger protein 145 | -0.0708233 |
| NRG1 | neuregulin 1 | -0.066386 |
| RTN4 | reticulon 4 | -0.06606 |
| VIM | vimentin | -0.0656157 |
| ENO1 | enolase 1, (alpha) | -0.0618819 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0600634 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.058254 |
| SMYD3 | SET and MYND domain containing 3 | -0.0535462 |
| EGR1 | early growth response 1 | -0.0520144 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0518617 |
| COPA | coatomer protein complex, subunit alpha | -0.0492315 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0487796 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.047979 |
| NBAS | neuroblastoma amplified sequence | -0.0474684 |
| TXNRD1 | thioredoxin reductase 1 | -0.0467879 |
| B2M | beta-2-microglobulin | -0.0450244 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.044528 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.042994 |
| PDE10A | phosphodiesterase 10A | -0.0419363 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0414188 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0412457 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0405469 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0403017 |
| ZNF292 | zinc finger protein 292 | -0.0401345 |
| LDHA | lactate dehydrogenase A | -0.0400721 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0398078 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0392388 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0390473 |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) | -0.0388161 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0387591 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0382598 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0373041 |
| NEDD1 | neural precursor cell expressed, developmentally down-regulated 1 | -0.0370222 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0368749 |
| USP33 | ubiquitin specific peptidase 33 | -0.0368065 |
| VGF | VGF nerve growth factor inducible | -0.0367668 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | -0.0364584 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0359744 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0355137 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0349047 |
| BBX | bobby sox homolog (Drosophila) | -0.0345909 |
| FMNL2 | formin-like 2 | -0.0343875 |
| VMP1 | vacuole membrane protein 1 | -0.0343303 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0338434 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0338154 |
| USP3 | ubiquitin specific peptidase 3 | -0.0336382 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0335651 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0333915 |
| MATR3 | matrin 3 | -0.0332908 |
| NUP58 | nucleoporin 58 | -0.0326647 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0323455 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0322634 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0321401 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0321148 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.032008 |
| SRP54 | signal recognition particle 54kDa | -0.0317238 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0317088 |
| CDC27 | cell division cycle 27 | -0.0314458 |
| VGLL4 | vestigial-like family member 4 | -0.0313178 |
| VEGFA | vascular endothelial growth factor A | -0.0310058 |
| TET2 | tet methylcytosine dioxygenase 2 | -0.0308562 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0307898 |
| MED13 | mediator complex subunit 13 | -0.030584 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0304428 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.030369 |
| MORF4L2 | mortality factor 4 like 2 | -0.0303243 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0300359 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0299154 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0298799 |
| RFX7 | regulatory factor X, 7 | -0.0298648 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0298044 |
| TCF12 | transcription factor 12 | -0.0296558 |
| GPHN | gephyrin | -0.0295966 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | -0.0295722 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0295339 |
| RORA | RAR-related orphan receptor A | -0.0295217 |
| KLHL24 | kelch-like family member 24 | -0.0294991 |
| INHBA | inhibin, beta A | -0.0294414 |
| TNPO3 | transportin 3 | -0.0292507 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0291027 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0290885 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0287728 |
| STK17A | serine/threonine kinase 17a | -0.0287284 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0287052 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0286016 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0284678 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0284439 |
| MORC3 | MORC family CW-type zinc finger 3 | -0.0284354 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0284229 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0283202 |
| DST | dystonin | -0.0282699 |
| MCL1 | myeloid cell leukemia 1 | -0.0281754 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0279985 |
