| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.33303 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.124199 |
| LAMC2 | laminin, gamma 2 | 0.123455 |
| PLEC | plectin | 0.122837 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.113807 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.111865 |
| AHNAK | AHNAK nucleoprotein | 0.111303 |
| LAMB3 | laminin, beta 3 | 0.104553 |
| TMSB4X | thymosin beta 4, X-linked | 0.0919372 |
| DSPP | dentin sialophosphoprotein | 0.0918407 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0890731 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.085893 |
| LOC112694756 | uncharaterized LOC112694756 | 0.080711 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.078538 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0742812 |
| EFNA5 | ephrin-A5 | 0.0710664 |
| FBXO32 | F-box protein 32 | 0.0703376 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0699488 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0689769 |
| UBC | ubiquitin C | 0.0683913 |
| KRT7 | keratin 7, type II | 0.0679652 |
| LMO7 | LIM domain 7 | 0.0671437 |
| NAV2 | neuron navigator 2 | 0.0643281 |
| ACTG1 | actin gamma 1 | 0.0611254 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0598816 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0552154 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0551526 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.053871 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0525033 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0517323 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0509467 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0503179 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0500231 |
| MYO6 | myosin VI | 0.0493439 |
| FN1 | fibronectin 1 | 0.0488797 |
| ERBIN | erbb2 interacting protein | 0.0487334 |
| DSG2 | desmoglein 2 | 0.0484824 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0483624 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0482313 |
| MYO5B | myosin VB | 0.0467982 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0462915 |
| EGFR | epidermal growth factor receptor | 0.0457062 |
| FLNB | filamin B, beta | 0.0451671 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0443432 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.043513 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0426038 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0425837 |
| MYO10 | myosin X | 0.0424476 |
| MSN | moesin | 0.0420875 |
| VGLL3 | vestigial-like family member 3 | 0.0419 |
| FLNA | filamin A, alpha | 0.0415642 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0414375 |
| MAP1B | microtubule-associated protein 1B | 0.0413137 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0412547 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.041192 |
| SMAD3 | SMAD family member 3 | 0.0407283 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0400807 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0396713 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0391155 |
| EZR | ezrin | 0.0390905 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0389302 |
| H1-0 | H1.0 linker histone | 0.0387691 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0382826 |
| PTK2 | protein tyrosine kinase 2 | 0.0381994 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0380505 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.037988 |
| SDC4 | syndecan 4 | 0.0376655 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0374752 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0372742 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0371233 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.037119 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0370557 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0369607 |
| CD44 | CD44 molecule (Indian blood group) | 0.0367741 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0367131 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0364318 |
| RNF213 | ring finger protein 213 | 0.0363597 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0362971 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0360967 |
| OSMR | oncostatin M receptor | 0.0358541 |
| RHOA | ras homolog family member A | 0.0358413 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0357897 |
| ATXN1 | ataxin 1 | 0.0354221 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0352598 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0350684 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0349611 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0348607 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0344956 |
| KRT18 | keratin 18, type I | 0.0343118 |
| MX1 | MX dynamin-like GTPase 1 | 0.0340617 |
| TPI1 | triosephosphate isomerase 1 | 0.0339901 |
| RPL3 | ribosomal protein L3 | 0.0338783 |
| TPM3 | tropomyosin 3 | 0.0336586 |
| RCOR1 | REST corepressor 1 | 0.0334519 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0334114 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0333541 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0333471 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.0333423 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0333083 |
| HDLBP | high density lipoprotein binding protein | 0.0333057 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.124743 |
| FTL | ferritin, light polypeptide | -0.0817108 |
| RPL35A | ribosomal protein L35a | -0.0704256 |
| RPS23 | ribosomal protein S23 | -0.038223 |
| HMGA1 | high mobility group AT-hook 1 | -0.03736 |
| RPL9 | ribosomal protein L9 | -0.0363373 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0345368 |
| RPS29 | ribosomal protein S29 | -0.0327544 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0307607 |
| RPLP1 | ribosomal protein, large, P1 | -0.0299618 |
| RNF145 | ring finger protein 145 | -0.0274806 |
| RPS13 | ribosomal protein S13 | -0.0273785 |
| TMSB10 | thymosin beta 10 | -0.0266803 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0266512 |
| RPL31 | ribosomal protein L31 | -0.0262604 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0254222 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0252601 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0229336 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0229265 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0222733 |
| RPL37A | ribosomal protein L37a | -0.0220403 |
| TFG | TRK-fused gene | -0.0216743 |
| RPS8 | ribosomal protein S8 | -0.0211135 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0201471 |
| CCNL1 | cyclin L1 | -0.0195236 |
| RPS25 | ribosomal protein S25 | -0.0192967 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0192138 |
| RPL34 | ribosomal protein L34 | -0.0190422 |
| RPS27 | ribosomal protein S27 | -0.0185909 |
| NUP58 | nucleoporin 58 | -0.0177834 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.017647 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0175481 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0168307 |
| RPS10 | ribosomal protein S10 | -0.0167283 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0163654 |
| QKI | QKI, KH domain containing, RNA binding | -0.0161125 |
| USP3 | ubiquitin specific peptidase 3 | -0.0160239 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.0148896 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0143463 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0140731 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0140537 |
| MXD1 | MAX dimerization protein 1 | -0.014036 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0140238 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0136957 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0129604 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0128454 |
| RPS19 | ribosomal protein S19 | -0.0127779 |
| RPS27A | ribosomal protein S27a | -0.012744 |
| RPL28 | ribosomal protein L28 | -0.0125093 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0125006 |
| RPS17 | ribosomal protein S17 | -0.0123537 |
| RPS14 | ribosomal protein S14 | -0.0122817 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0122126 |
| SELENOK | selenoprotein K | -0.0121163 |
| RPLP2 | ribosomal protein, large, P2 | -0.012112 |
| IER3 | immediate early response 3 | -0.0121039 |
| FOSL1 | FOS-like antigen 1 | -0.0120467 |
| RHEB | Ras homolog enriched in brain | -0.0119898 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0119335 |
| RPL36 | ribosomal protein L36 | -0.0119264 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.0118547 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0117596 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0117532 |
| RPS16 | ribosomal protein S16 | -0.0116784 |
| FAM162A | family with sequence similarity 162, member A | -0.0112628 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0112294 |
| RPS24 | ribosomal protein S24 | -0.0112251 |
| RPL38 | ribosomal protein L38 | -0.0112192 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.011116 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0109656 |
| RPL36A | ribosomal protein L36a | -0.0107884 |
| RPL11 | ribosomal protein L11 | -0.0107738 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.0106801 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0106334 |
| RPS15 | ribosomal protein S15 | -0.0105789 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0105419 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0105003 |
| TMEM131L | transmembrane 131 like | -0.0104796 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0104451 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0104118 |
| RYK | receptor-like tyrosine kinase | -0.0103738 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0102799 |
| RPS20 | ribosomal protein S20 | -0.0102039 |
| OLA1 | Obg-like ATPase 1 | -0.0101091 |
| PUM2 | pumilio RNA-binding family member 2 | -0.00997218 |
| PDS5B | PDS5 cohesin associated factor B | -0.0099463 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.00982317 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | -0.00978253 |
| RPL12 | ribosomal protein L12 | -0.00977526 |
| RPS2 | ribosomal protein S2 | -0.00966148 |
| SFTPA1 | surfactant protein A1 | -0.00963225 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.00961128 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0094817 |
| B2M | beta-2-microglobulin | -0.00945533 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0094352 |
| CD83 | CD83 molecule | -0.00941687 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.00939315 |
| DENND4A | DENN/MADD domain containing 4A | -0.00925451 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.00920745 |
| HMGB1 | high mobility group box 1 | -0.0092005 |
