| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.148714 |
| GDA | guanine deaminase | 0.139803 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.123634 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.115358 |
| COL5A2 | collagen, type V, alpha 2 | 0.105759 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0970455 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0933274 |
| PDE10A | phosphodiesterase 10A | 0.085538 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0811901 |
| KYNU | kynureninase | 0.0767177 |
| FMNL2 | formin-like 2 | 0.074605 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0736885 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0721229 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0703098 |
| MYOF | myoferlin | 0.0675979 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0664895 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0656198 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0649424 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0648305 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0644947 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0623727 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0620493 |
| GRAMD1B | GRAM domain containing 1B | 0.0606463 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0605495 |
| CD109 | CD109 molecule | 0.0588385 |
| DST | dystonin | 0.0588227 |
| NEK7 | NIMA-related kinase 7 | 0.0586576 |
| ASPH | aspartate beta-hydroxylase | 0.0569341 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0559033 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0552243 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0547944 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0540626 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.053878 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0533714 |
| MCL1 | myeloid cell leukemia 1 | 0.0533015 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0515809 |
| EZR | ezrin | 0.0512042 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0505514 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0498543 |
| NRCAM | neuronal cell adhesion molecule | 0.0496733 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0496619 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0492464 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0492068 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0480499 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0471046 |
| SPAG9 | sperm associated antigen 9 | 0.0450585 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0437396 |
| FLNB | filamin B, beta | 0.041702 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0409198 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0407901 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0406591 |
| SMYD3 | SET and MYND domain containing 3 | 0.0405278 |
| PCBP3 | poly(rC) binding protein 3 | 0.0403584 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.039899 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0397802 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0396351 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0392757 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0387145 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0386756 |
| SMAD2 | SMAD family member 2 | 0.03776 |
| OGA | O-GlcNAcase | 0.0369797 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0369204 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0361888 |
| RPL3 | ribosomal protein L3 | 0.0361608 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0360501 |
| CDH13 | cadherin 13 | 0.0357306 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0355174 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0352997 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0352899 |
| ENAH | enabled homolog (Drosophila) | 0.0350823 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0350805 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0348545 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0342645 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0340761 |
| VCL | vinculin | 0.0333926 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0333925 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0330855 |
| TNPO1 | transportin 1 | 0.0329018 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.03284 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0327414 |
| RTN4 | reticulon 4 | 0.0325047 |
| NCKAP1 | NCK-associated protein 1 | 0.0315763 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0315551 |
| BMERB1 | bMERB domain containing 1 | 0.0307737 |
| RPS4X | ribosomal protein S4, X-linked | 0.0304479 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0304438 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0303576 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0302431 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0302194 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0300463 |
| RBM39 | RNA binding motif protein 39 | 0.0299884 |
| ALPK2 | alpha-kinase 2 | 0.0298537 |
| LAMA1 | laminin, alpha 1 | 0.0298156 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.029613 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0295354 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0293825 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0292406 |
| PGK1 | phosphoglycerate kinase 1 | 0.0290274 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0288235 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0286879 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.127097 |
| TMSB10 | thymosin beta 10 | -0.117308 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.107744 |
| VIM | vimentin | -0.097741 |
| RPS6 | ribosomal protein S6 | -0.0663723 |
| RPLP1 | ribosomal protein, large, P1 | -0.0636888 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0595703 |
| RPS19 | ribosomal protein S19 | -0.0560252 |
| FTL | ferritin, light polypeptide | -0.0546225 |
| RPL35A | ribosomal protein L35a | -0.0522886 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0518722 |
| RPS23 | ribosomal protein S23 | -0.0466941 |
| FN1 | fibronectin 1 | -0.0462095 |
| RPL34 | ribosomal protein L34 | -0.0451427 |
| RPL12 | ribosomal protein L12 | -0.044596 |
| RPS27 | ribosomal protein S27 | -0.0381485 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0361318 |
| RPL31 | ribosomal protein L31 | -0.0360607 |
| RPS8 | ribosomal protein S8 | -0.0350771 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0350002 |
| RPS29 | ribosomal protein S29 | -0.034864 |
| MT2A | metallothionein 2A | -0.0337947 |
| PTMA | prothymosin, alpha | -0.031164 |
| RPL23 | ribosomal protein L23 | -0.0308997 |
| RPS14 | ribosomal protein S14 | -0.0299385 |
| RPS13 | ribosomal protein S13 | -0.0297424 |
| CANX | calnexin | -0.0294891 |
| EGR1 | early growth response 1 | -0.0282965 |
| RPL35 | ribosomal protein L35 | -0.0271985 |
| RPL32 | ribosomal protein L32 | -0.0268624 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0265474 |
| RPL37A | ribosomal protein L37a | -0.0256383 |
| RPL36 | ribosomal protein L36 | -0.0249863 |
| ASTN2 | astrotactin 2 | -0.0246447 |
| ENO1 | enolase 1, (alpha) | -0.0240186 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0234173 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0222482 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0218348 |
| RPS17 | ribosomal protein S17 | -0.0214576 |
| IL6 | interleukin 6 | -0.0213934 |
| RPLP2 | ribosomal protein, large, P2 | -0.0211823 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0208138 |
| RPS2 | ribosomal protein S2 | -0.02017 |
| POTEF | POTE ankyrin domain family, member F | -0.0193714 |
| RPS16 | ribosomal protein S16 | -0.0190895 |
| CXXC1 | CXXC finger protein 1 | -0.0188944 |
| RPL28 | ribosomal protein L28 | -0.0187614 |
| ATF4 | activating transcription factor 4 | -0.0182677 |
| LSAMP | limbic system-associated membrane protein | -0.0180928 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0170754 |
| RPL27 | ribosomal protein L27 | -0.016871 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0167607 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0167583 |
| HMGB1 | high mobility group box 1 | -0.016438 |
| RPS21 | ribosomal protein S21 | -0.016304 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.01599 |
| CALR | calreticulin | -0.0158023 |
| RPL26 | ribosomal protein L26 | -0.0156446 |
| RPL21 | ribosomal protein L21 | -0.0154353 |
| CLU | clusterin | -0.0152572 |
| RPS26 | ribosomal protein S26 | -0.0150372 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0146255 |
| RPS15 | ribosomal protein S15 | -0.0145638 |
| HMGA1 | high mobility group AT-hook 1 | -0.0142841 |
| RPS28 | ribosomal protein S28 | -0.0141383 |
| RPL13A | ribosomal protein L13a | -0.0140408 |
| AGR2 | anterior gradient 2 | -0.0138741 |
| TBCA | tubulin folding cofactor A | -0.013755 |
| RPL5 | ribosomal protein L5 | -0.0134873 |
| RPS5 | ribosomal protein S5 | -0.0133371 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0132562 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0132162 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0132105 |
| CST3 | cystatin C | -0.0128216 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0126915 |
| PRELID2 | PRELI domain containing 2 | -0.0125343 |
| GOLGB1 | golgin B1 | -0.0124594 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0124433 |
| RPS25 | ribosomal protein S25 | -0.0124126 |
| RPS20 | ribosomal protein S20 | -0.0123244 |
| GLRX | glutaredoxin (thioltransferase) | -0.0123163 |
| KRT19 | keratin 19, type I | -0.0121757 |
| SSR4 | signal sequence receptor, delta | -0.0119023 |
| PCDH15 | protocadherin-related 15 | -0.0116902 |
| S100A9 | S100 calcium binding protein A9 | -0.0115903 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0115249 |
| AUTS2 | autism susceptibility candidate 2 | -0.0114688 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0113961 |
| VEGFA | vascular endothelial growth factor A | -0.0112468 |
| RPL7 | ribosomal protein L7 | -0.0112455 |
| RPL9 | ribosomal protein L9 | -0.0110992 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0108724 |
| MRPS2 | mitochondrial ribosomal protein S2 | -0.0108567 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -0.0108519 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0107471 |
| PAPPA2 | pappalysin 2 | -0.010682 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.010524 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0104438 |
| ICE2 | interactor of little elongation complex ELL subunit 2 | -0.0103539 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0103182 |
