| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.138788 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.131229 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.103618 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0857567 |
| ACTN4 | actinin, alpha 4 | 0.0821605 |
| DST | dystonin | 0.0811382 |
| SEPTIN9 | septin 9 | 0.0804 |
| RPS16 | ribosomal protein S16 | 0.0803809 |
| SMAD3 | SMAD family member 3 | 0.0785604 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0678763 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0671993 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0659117 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0646336 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0625823 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0592159 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0589485 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0582356 |
| AHNAK | AHNAK nucleoprotein | 0.057084 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0563375 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.054446 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0543421 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0533806 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0533633 |
| NUP98 | nucleoporin 98kDa | 0.0524273 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0523131 |
| PTK2 | protein tyrosine kinase 2 | 0.0502956 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0500309 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0500263 |
| INTS6 | integrator complex subunit 6 | 0.0498977 |
| CD44 | CD44 molecule (Indian blood group) | 0.0497918 |
| HMGA2 | high mobility group AT-hook 2 | 0.0492344 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0491119 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0476401 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0462362 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0455565 |
| MT2A | metallothionein 2A | 0.0451368 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0450449 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0435585 |
| ASPH | aspartate beta-hydroxylase | 0.0433624 |
| PLEC | plectin | 0.0432134 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0427033 |
| ANO6 | anoctamin 6 | 0.0422898 |
| MYO10 | myosin X | 0.0421775 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0408776 |
| SMYD3 | SET and MYND domain containing 3 | 0.0406219 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0405558 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0405474 |
| NAV2 | neuron navigator 2 | 0.0401671 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0396184 |
| MYOF | myoferlin | 0.0390838 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0382698 |
| ACTG1 | actin gamma 1 | 0.0381921 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0380519 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0371896 |
| PKM | pyruvate kinase, muscle | 0.0368407 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0365492 |
| NF1 | neurofibromin 1 | 0.0363844 |
| ATXN1 | ataxin 1 | 0.0363151 |
| RNF213 | ring finger protein 213 | 0.0362036 |
| RASAL2 | RAS protein activator like 2 | 0.0353856 |
| MED13L | mediator complex subunit 13-like | 0.0353493 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.03478 |
| RPS24 | ribosomal protein S24 | 0.0347175 |
| RPLP2 | ribosomal protein, large, P2 | 0.0346934 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0336547 |
| RPS12 | ribosomal protein S12 | 0.0324043 |
| CARD18 | caspase recruitment domain family, member 18 | 0.0324015 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0323588 |
| APP | amyloid beta (A4) precursor protein | 0.032237 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.032095 |
| FLNA | filamin A, alpha | 0.0320165 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0319184 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0316493 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0315696 |
| RPL11 | ribosomal protein L11 | 0.0315554 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0314382 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0313842 |
| TPX2 | TPX2, microtubule-associated | 0.0313347 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0311877 |
| SATB2 | SATB homeobox 2 | 0.031132 |
| RPS3 | ribosomal protein S3 | 0.0311211 |
| MCL1 | myeloid cell leukemia 1 | 0.0311111 |
| CTBP2 | C-terminal binding protein 2 | 0.0309654 |
| ATG7 | autophagy related 7 | 0.0307924 |
| TMSB10 | thymosin beta 10 | 0.0306962 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0301023 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0298671 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0293226 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0292522 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0292404 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0292194 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.029126 |
| EFNA5 | ephrin-A5 | 0.0290929 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0289551 |
| KRT8 | keratin 8, type II | 0.028923 |
| USP34 | ubiquitin specific peptidase 34 | 0.028603 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0285407 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0283812 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0283629 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0282292 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.156161 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.120595 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0833791 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0488223 |
| VIM | vimentin | -0.04478 |
| S100A6 | S100 calcium binding protein A6 | -0.0248684 |
| CANX | calnexin | -0.0247268 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0178807 |
| GOLGA4 | golgin A4 | -0.0174345 |
| FOSL1 | FOS-like antigen 1 | -0.0173343 |
| ZNF292 | zinc finger protein 292 | -0.0164053 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0163056 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.016304 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0154316 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0151178 |
| ZFP36 | ZFP36 ring finger protein | -0.0148643 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0144343 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0132583 |
| TMEM41B | transmembrane protein 41B | -0.0129468 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0126223 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0126102 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.012549 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0124179 |
| CDCP1 | CUB domain containing protein 1 | -0.0122718 |
| WDR45B | WD repeat domain 45B | -0.0119998 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0119383 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0116629 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0113297 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0108645 |
| TMEM263 | transmembrane protein 263 | -0.0103745 |
| RLF | rearranged L-myc fusion | -0.0103334 |
| TMEM165 | transmembrane protein 165 | -0.0103306 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0102843 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.0101777 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.00998333 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0099592 |
| USP3 | ubiquitin specific peptidase 3 | -0.00978062 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.00961429 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.00955341 |
| SEC24A | SEC24 family member A | -0.00945292 |
| TPM4 | tropomyosin 4 | -0.0092282 |
| NDRG1 | N-myc downstream regulated 1 | -0.00892809 |
| LMAN1 | lectin, mannose-binding, 1 | -0.00865329 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00863598 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.00844091 |
| MTDH | metadherin | -0.00843575 |
| NUCB2 | nucleobindin 2 | -0.00835904 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.00831668 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.00824215 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00816373 |
| CDK19 | cyclin-dependent kinase 19 | -0.00811312 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00810738 |
| TPD52 | tumor protein D52 | -0.00809188 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.00771424 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.00768971 |
| SRP54 | signal recognition particle 54kDa | -0.00761344 |
| NUS1 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) | -0.00756521 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.00750076 |
| ELP2 | elongator acetyltransferase complex subunit 2 | -0.00742213 |
| RNF149 | ring finger protein 149 | -0.00734043 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.00721022 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | -0.00717949 |
| PRRC1 | proline-rich coiled-coil 1 | -0.00712614 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.00710308 |
| WASF2 | WAS protein family, member 2 | -0.00707849 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.00707218 |
| RIOK3 | RIO kinase 3 | -0.00705384 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.00699302 |
| H1-0 | H1.0 linker histone | -0.00697614 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0069703 |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) | -0.00692939 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.00692479 |
| GOLT1B | golgi transport 1B | -0.00688977 |
| FAM13A | family with sequence similarity 13, member A | -0.00688783 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.00686526 |
| NCK1 | NCK adaptor protein 1 | -0.00684773 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.00676884 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00676527 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0067209 |
| ARRDC3 | arrestin domain containing 3 | -0.00671015 |
| TMEM39A | transmembrane protein 39A | -0.00670849 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.00669725 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.00669422 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.00668173 |
| CLINT1 | clathrin interactor 1 | -0.00666307 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | -0.00665405 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) | -0.00660088 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0065873 |
| ADM | adrenomedullin | -0.00657559 |
| SEC24D | SEC24 family member D | -0.00657084 |
| HELB | helicase (DNA) B | -0.00652886 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 | -0.0065247 |
| SELENOS | selenoprotein S | -0.00645329 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00643121 |
| NKTR | natural killer cell triggering receptor | -0.00638651 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -0.00638188 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.00637668 |
| UFL1 | UFM1-specific ligase 1 | -0.00637297 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | -0.00636847 |
| NIPSNAP2 | nipsnap homolog 2 | -0.00633707 |
