| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.135245 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.126322 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.120481 |
| EZR | ezrin | 0.112917 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.102272 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0886473 |
| LAMB3 | laminin, beta 3 | 0.0857861 |
| LAMA4 | laminin, alpha 4 | 0.0789489 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0778544 |
| LAMC2 | laminin, gamma 2 | 0.0738702 |
| SMAD3 | SMAD family member 3 | 0.0718334 |
| TMSB4X | thymosin beta 4, X-linked | 0.0702672 |
| DSPP | dentin sialophosphoprotein | 0.0691922 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0674401 |
| KRT18 | keratin 18, type I | 0.0638129 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.05959 |
| PLEC | plectin | 0.0574935 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0572246 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.057038 |
| RUNX1 | runt-related transcription factor 1 | 0.0567433 |
| DSG2 | desmoglein 2 | 0.0517414 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0514237 |
| H1-0 | H1.0 linker histone | 0.0495315 |
| SEPTIN9 | septin 9 | 0.0494011 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0480457 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0458191 |
| WWC1 | WW and C2 domain containing 1 | 0.0450125 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0447223 |
| MYOF | myoferlin | 0.0445912 |
| CANX | calnexin | 0.0444976 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0438798 |
| RNF213 | ring finger protein 213 | 0.0436258 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0432478 |
| EMP1 | epithelial membrane protein 1 | 0.0430979 |
| SVIL | supervillin | 0.0419305 |
| CD44 | CD44 molecule (Indian blood group) | 0.0417796 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0414352 |
| FLNB | filamin B, beta | 0.0413072 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0406952 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0405228 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0404041 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0388019 |
| TGM2 | transglutaminase 2 | 0.0386442 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.038565 |
| OSMR | oncostatin M receptor | 0.0380193 |
| MKI67 | marker of proliferation Ki-67 | 0.0375712 |
| PGK1 | phosphoglycerate kinase 1 | 0.0375469 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0375004 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0374585 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0372095 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0369627 |
| SMYD3 | SET and MYND domain containing 3 | 0.0368042 |
| LMO7 | LIM domain 7 | 0.0367043 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0366711 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0361475 |
| AFDN | afadin, adherens junction formation factor | 0.0357216 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0356888 |
| FAM3C | family with sequence similarity 3, member C | 0.0355074 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0354494 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0353917 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0353761 |
| EFNA5 | ephrin-A5 | 0.0350628 |
| APP | amyloid beta (A4) precursor protein | 0.0350145 |
| EHF | ets homologous factor | 0.0349157 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0348843 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0345402 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0339523 |
| HDLBP | high density lipoprotein binding protein | 0.0336068 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0334796 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0329891 |
| NAV2 | neuron navigator 2 | 0.0329286 |
| TXNIP | thioredoxin interacting protein | 0.0328264 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.032731 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0326846 |
| EGFR | epidermal growth factor receptor | 0.0323023 |
| KRT8 | keratin 8, type II | 0.0320435 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.031836 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0318161 |
| ACTN4 | actinin, alpha 4 | 0.0316898 |
| H1-10 | H1.10 linker histone | 0.0315593 |
| EPCAM | epithelial cell adhesion molecule | 0.0314677 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0313292 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0312338 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.031047 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0308156 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0306062 |
| CD2AP | CD2-associated protein | 0.0305927 |
| RPL3 | ribosomal protein L3 | 0.0301148 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0301126 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0300351 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0298183 |
| JMJD1C | jumonji domain containing 1C | 0.0298069 |
| DST | dystonin | 0.0296658 |
| H1-4 | H1.4 linker histone, cluster member | 0.0296076 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0289311 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0288267 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0287045 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0286991 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0284406 |
| ATP11A | ATPase, class VI, type 11A | 0.028429 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL35A | ribosomal protein L35a | -0.119605 |
| HMGA1 | high mobility group AT-hook 1 | -0.0876454 |
| FTL | ferritin, light polypeptide | -0.0702861 |
| PTMA | prothymosin, alpha | -0.0684142 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.062761 |
| TMSB10 | thymosin beta 10 | -0.0611298 |
| RPL31 | ribosomal protein L31 | -0.0555754 |
| RPS6 | ribosomal protein S6 | -0.0543072 |
| RPS8 | ribosomal protein S8 | -0.0506662 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0482786 |
| RPS13 | ribosomal protein S13 | -0.0445825 |
| RPL37A | ribosomal protein L37a | -0.0402966 |
| RPS23 | ribosomal protein S23 | -0.0396471 |
| POTEF | POTE ankyrin domain family, member F | -0.0365008 |
| RPS19 | ribosomal protein S19 | -0.0354425 |
| RPS29 | ribosomal protein S29 | -0.0352134 |
| RPL9 | ribosomal protein L9 | -0.0344918 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.0334161 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0307454 |
| INTS6 | integrator complex subunit 6 | -0.0299568 |
| RPS10 | ribosomal protein S10 | -0.0295767 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0290322 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0272038 |
| RPS25 | ribosomal protein S25 | -0.0268914 |
| RPS14 | ribosomal protein S14 | -0.0268644 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0242274 |
| HLA-A | major histocompatibility complex, class I, A | -0.0241819 |
| RPLP1 | ribosomal protein, large, P1 | -0.0239955 |
| RPS20 | ribosomal protein S20 | -0.0236632 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0236195 |
| RPS27 | ribosomal protein S27 | -0.0234205 |
| RPL34 | ribosomal protein L34 | -0.0233205 |
| RPS15 | ribosomal protein S15 | -0.0228272 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.022273 |
| RPL11 | ribosomal protein L11 | -0.0222015 |
| RPS16 | ribosomal protein S16 | -0.0220614 |
| CLDN4 | claudin 4 | -0.0206741 |
| ACTG1 | actin gamma 1 | -0.0205335 |
| SYT14 | synaptotagmin XIV | -0.0196002 |
| RPS17 | ribosomal protein S17 | -0.0190316 |
| ABHD3 | abhydrolase domain containing 3 | -0.0189541 |
| HLA-B | major histocompatibility complex, class I, B | -0.0189481 |
| EGR1 | early growth response 1 | -0.0186201 |
| RPL30 | ribosomal protein L30 | -0.0185289 |
| RPL28 | ribosomal protein L28 | -0.0181039 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0179708 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0177456 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0175854 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0174866 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0172819 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0166308 |
| RPS27A | ribosomal protein S27a | -0.0165987 |
| RPL27 | ribosomal protein L27 | -0.0160029 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.015623 |
| RPS11 | ribosomal protein S11 | -0.015193 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0145833 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0142847 |
| RPLP2 | ribosomal protein, large, P2 | -0.0140541 |
| RPL15 | ribosomal protein L15 | -0.0140426 |
| RPL12 | ribosomal protein L12 | -0.013807 |
| VEGFA | vascular endothelial growth factor A | -0.0134327 |
| TPM4 | tropomyosin 4 | -0.0131633 |
| S100A11 | S100 calcium binding protein A11 | -0.0131483 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0131453 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | -0.0131029 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | -0.0130893 |
| ATF4 | activating transcription factor 4 | -0.0129113 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0126981 |
| IGF2 | insulin-like growth factor 2 | -0.0124482 |
| SQSTM1 | sequestosome 1 | -0.0124317 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0123033 |
| RPL36A | ribosomal protein L36a | -0.0122574 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0121681 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0121208 |
| RPL39 | ribosomal protein L39 | -0.0117595 |
| RPL7A | ribosomal protein L7a | -0.0117375 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0116827 |
| LRRC23 | leucine rich repeat containing 23 | -0.0116222 |
| MMP7 | matrix metallopeptidase 7 | -0.0115994 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.011573 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0115655 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.011542 |
| DAPK1 | death-associated protein kinase 1 | -0.0114917 |
| RPS28 | ribosomal protein S28 | -0.0113556 |
| RPL10A | ribosomal protein L10a | -0.0113343 |
| COX7C | cytochrome c oxidase subunit VIIc | -0.0113245 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0112707 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0112539 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0111432 |
| HMGB1 | high mobility group box 1 | -0.0111311 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0110762 |
| SHISA5 | shisa family member 5 | -0.0107514 |
| CTSD | cathepsin D | -0.0107241 |
| ATP6V0C | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | -0.0106196 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0104723 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0104153 |
| RPL37 | ribosomal protein L37 | -0.0103542 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0103481 |
| JUP | junction plakoglobin | -0.0103185 |
| TBCA | tubulin folding cofactor A | -0.010275 |
