| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL3 | ribosomal protein L3 | 0.143658 |
| FRMD6 | FERM domain containing 6 | 0.118009 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0840055 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0762605 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0731029 |
| EXT1 | exostosin glycosyltransferase 1 | 0.067243 |
| H1-4 | H1.4 linker histone, cluster member | 0.0663667 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0661933 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0636268 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0629137 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0617633 |
| SGMS2 | sphingomyelin synthase 2 | 0.0606725 |
| FLNB | filamin B, beta | 0.0590609 |
| HMGA2 | high mobility group AT-hook 2 | 0.0577794 |
| NAV2 | neuron navigator 2 | 0.054019 |
| CAPRIN2 | caprin family member 2 | 0.0521701 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0518743 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.049411 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0484588 |
| UPP1 | uridine phosphorylase 1 | 0.0474708 |
| RPS12 | ribosomal protein S12 | 0.0471582 |
| RPS18 | ribosomal protein S18 | 0.046476 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0456628 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0447444 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0442408 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.043444 |
| RCOR1 | REST corepressor 1 | 0.0430891 |
| MKI67 | marker of proliferation Ki-67 | 0.042159 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0419134 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0416439 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0402522 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0391123 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0379378 |
| RPL4 | ribosomal protein L4 | 0.0377075 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0361053 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 0.0358823 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0350198 |
| FLNA | filamin A, alpha | 0.0346793 |
| TPI1 | triosephosphate isomerase 1 | 0.0340274 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.0339958 |
| RUNX1 | runt-related transcription factor 1 | 0.0334992 |
| CORO1C | coronin, actin binding protein, 1C | 0.0334101 |
| FRMD4A | FERM domain containing 4A | 0.033363 |
| NCKAP1 | NCK-associated protein 1 | 0.0332666 |
| RRBP1 | ribosome binding protein 1 | 0.0329441 |
| MCL1 | myeloid cell leukemia 1 | 0.0322596 |
| RPL38 | ribosomal protein L38 | 0.0322528 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0320499 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0318777 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0316707 |
| SLC38A2 | solute carrier family 38, member 2 | 0.03112 |
| SMTN | smoothelin | 0.0307328 |
| STX3 | syntaxin 3 | 0.0303987 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0302441 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0292409 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0291397 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0290602 |
| RPL14 | ribosomal protein L14 | 0.028926 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0286729 |
| PLEC | plectin | 0.0285867 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0284999 |
| GSE1 | Gse1 coiled-coil protein | 0.0284856 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0284004 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | 0.0283418 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0283193 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0280558 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0279386 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0271734 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0267886 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0264114 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0263711 |
| MYO10 | myosin X | 0.0263171 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0262495 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0262338 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0260015 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0258863 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0258296 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0258281 |
| CLTC | clathrin, heavy chain (Hc) | 0.0255708 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0255461 |
| HDLBP | high density lipoprotein binding protein | 0.0255389 |
| EZR | ezrin | 0.0252393 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0250953 |
| TPM3 | tropomyosin 3 | 0.0250821 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0250248 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0249929 |
| RPL5 | ribosomal protein L5 | 0.0246426 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0245671 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0245502 |
| NUDC | nudC nuclear distribution protein | 0.0245145 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.024495 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0243613 |
| GPHN | gephyrin | 0.02421 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0242077 |
| STK4 | serine/threonine kinase 4 | 0.0241293 |
| USP34 | ubiquitin specific peptidase 34 | 0.0241186 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0238725 |
| PTK2 | protein tyrosine kinase 2 | 0.0237972 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0236631 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0236498 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.108338 |
| MT2A | metallothionein 2A | -0.0977898 |
| RPL35A | ribosomal protein L35a | -0.091333 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0884019 |
| HMGA1 | high mobility group AT-hook 1 | -0.0834731 |
| UBC | ubiquitin C | -0.0802905 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0753957 |
| RPL9 | ribosomal protein L9 | -0.0747223 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.066677 |
| RPS27A | ribosomal protein S27a | -0.0620858 |
| TPM4 | tropomyosin 4 | -0.0615069 |
| TMSB10 | thymosin beta 10 | -0.0592465 |
| RPLP1 | ribosomal protein, large, P1 | -0.0547687 |
| POTEF | POTE ankyrin domain family, member F | -0.0541307 |
| RPL12 | ribosomal protein L12 | -0.0530635 |
| ENO1 | enolase 1, (alpha) | -0.0499004 |
| MTDH | metadherin | -0.0474084 |
| RPL30 | ribosomal protein L30 | -0.0467561 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0457385 |
| RPS8 | ribosomal protein S8 | -0.0438946 |
| PCBP2 | poly(rC) binding protein 2 | -0.0395929 |
| LDHA | lactate dehydrogenase A | -0.0392943 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0380562 |
| LDHB | lactate dehydrogenase B | -0.0379437 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0356623 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0353302 |
| FTL | ferritin, light polypeptide | -0.0350296 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0335256 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0329219 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0301856 |
| RIGI | RNA sensor RIG-I | -0.0289681 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0287378 |
| RAB3IP | RAB3A interacting protein | -0.0285506 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0284103 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0282106 |
| PFN1 | profilin 1 | -0.0279395 |
| CALD1 | caldesmon 1 | -0.0278993 |
| HMGB1 | high mobility group box 1 | -0.0278254 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0273291 |
| S100A6 | S100 calcium binding protein A6 | -0.0263586 |
| JUN | jun proto-oncogene | -0.0263143 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0262189 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0261422 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0260582 |
| CANX | calnexin | -0.0259277 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0254964 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0253356 |
| ASPH | aspartate beta-hydroxylase | -0.025193 |
| STC1 | stanniocalcin 1 | -0.0250236 |
| RPS19 | ribosomal protein S19 | -0.0245115 |
| GNAS | GNAS complex locus | -0.0242292 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0237553 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0236953 |
| RPS13 | ribosomal protein S13 | -0.0231978 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.023157 |
| HLA-A | major histocompatibility complex, class I, A | -0.0231446 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.0231306 |
| ZNF148 | zinc finger protein 148 | -0.0229105 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0222283 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0215979 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0215573 |
| RPL34 | ribosomal protein L34 | -0.0215188 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.021403 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0213231 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.021172 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0208674 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0207221 |
| PCNX4 | pecanex 4 | -0.0207054 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.020462 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0204452 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.020285 |
| TUBA1C | tubulin, alpha 1c | -0.0202265 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0194738 |
| MX2 | MX dynamin-like GTPase 2 | -0.019433 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0193483 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0192554 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0191145 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.019102 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0190777 |
| ATF4 | activating transcription factor 4 | -0.0189662 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0189247 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0189217 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0188567 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0187882 |
| RPL39 | ribosomal protein L39 | -0.0185619 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.018544 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0184321 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0184007 |
| MT1X | metallothionein 1X | -0.0181945 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0181898 |
| TMEM263 | transmembrane protein 263 | -0.0181274 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.0180257 |
| RPLP0 | ribosomal protein, large, P0 | -0.0178232 |
| CBX3 | chromobox homolog 3 | -0.0176343 |
| RNF169 | ring finger protein 169 | -0.017428 |
| RPS16 | ribosomal protein S16 | -0.0172118 |
| RPS20 | ribosomal protein S20 | -0.0170516 |
| VIM | vimentin | -0.0170482 |
| ANXA2 | annexin A2 | -0.0170086 |
| RPL10A | ribosomal protein L10a | -0.0167147 |
