| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lidocaine (hydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.108519 |
| FRMD4A | FERM domain containing 4A | 0.108263 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.105571 |
| COL5A1 | collagen, type V, alpha 1 | 0.103408 |
| CD44 | CD44 molecule (Indian blood group) | 0.0966492 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0905666 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0849446 |
| NAV1 | neuron navigator 1 | 0.0841051 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0838627 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0832921 |
| SMAD3 | SMAD family member 3 | 0.0755336 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0707203 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0670978 |
| AHNAK | AHNAK nucleoprotein | 0.0650199 |
| NRP1 | neuropilin 1 | 0.0640546 |
| FAM20C | family with sequence similarity 20, member C | 0.0637675 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0631746 |
| PLEC | plectin | 0.0625363 |
| MSN | moesin | 0.0600545 |
| COL7A1 | collagen, type VII, alpha 1 | 0.059121 |
| FHIT | fragile histidine triad | 0.0590649 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0576719 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0565857 |
| ANGPTL4 | angiopoietin-like 4 | 0.0559735 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0557126 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0549875 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0542705 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0541448 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0531703 |
| SP100 | SP100 nuclear antigen | 0.0517419 |
| RUNX1 | runt-related transcription factor 1 | 0.0517298 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0513852 |
| HDAC9 | histone deacetylase 9 | 0.0507541 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0502792 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0498602 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0486444 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0478785 |
| H1-0 | H1.0 linker histone | 0.047537 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.047532 |
| FLNB | filamin B, beta | 0.0471998 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0471868 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.047124 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0457696 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0446887 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0446482 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0441109 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0422672 |
| MX1 | MX dynamin-like GTPase 1 | 0.0421943 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0417354 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0410771 |
| LOXL2 | lysyl oxidase-like 2 | 0.0406651 |
| RNF213 | ring finger protein 213 | 0.0406392 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0405759 |
| IFI44L | interferon-induced protein 44-like | 0.0398929 |
| STC1 | stanniocalcin 1 | 0.0398727 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0396933 |
| RAD51B | RAD51 paralog B | 0.0386508 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0384678 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0378477 |
| SVIL | supervillin | 0.0378342 |
| MTSS1 | metastasis suppressor 1 | 0.0373618 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0372774 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0371042 |
| VEGFA | vascular endothelial growth factor A | 0.0369327 |
| DST | dystonin | 0.0365531 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0365305 |
| HMGA2 | high mobility group AT-hook 2 | 0.036191 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.036107 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | 0.0357421 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0351093 |
| TOP1 | topoisomerase (DNA) I | 0.0345471 |
| FLNA | filamin A, alpha | 0.0342458 |
| MCL1 | myeloid cell leukemia 1 | 0.0337332 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0337017 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0331946 |
| FAT1 | FAT atypical cadherin 1 | 0.0331544 |
| SMYD3 | SET and MYND domain containing 3 | 0.0326571 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0326071 |
| GLIS3 | GLIS family zinc finger 3 | 0.0325085 |
| MLPH | melanophilin | 0.0324154 |
| COL5A3 | collagen, type V, alpha 3 | 0.0323482 |
| TPM1 | tropomyosin 1 (alpha) | 0.0322276 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.031737 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0315001 |
| MED13L | mediator complex subunit 13-like | 0.0312257 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0311331 |
| RPS17 | ribosomal protein S17 | 0.0310557 |
| ACTN1 | actinin, alpha 1 | 0.0305093 |
| TPI1 | triosephosphate isomerase 1 | 0.0304823 |
| FN1 | fibronectin 1 | 0.0303066 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0301121 |
| TMEM178B | transmembrane protein 178B | 0.0300611 |
| EML5 | echinoderm microtubule associated protein like 5 | 0.030019 |
| PARD3 | par-3 family cell polarity regulator | 0.029704 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0296588 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.029435 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0293637 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0292928 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0289521 |
| AFDN | afadin, adherens junction formation factor | 0.0288528 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.179769 |
| FTL | ferritin, light polypeptide | -0.0798684 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0688908 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0648429 |
| COL1A2 | collagen, type I, alpha 2 | -0.0605471 |
| PTMA | prothymosin, alpha | -0.0599741 |
| GOLGA4 | golgin A4 | -0.0509025 |
| RPL35A | ribosomal protein L35a | -0.0392414 |
| CENPF | centromere protein F, 350/400kDa | -0.0338722 |
| TPM4 | tropomyosin 4 | -0.0333955 |
| IER3 | immediate early response 3 | -0.0331342 |
| SRP54 | signal recognition particle 54kDa | -0.0317198 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0302753 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0298982 |
| TMSB10 | thymosin beta 10 | -0.0292751 |
| CANX | calnexin | -0.0253679 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0251076 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0249981 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0245136 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0239558 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0235736 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.0234344 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0234129 |
| ADM | adrenomedullin | -0.0230047 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0224222 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0222922 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0222693 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0215942 |
| TPX2 | TPX2, microtubule-associated | -0.0211481 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0203632 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0199969 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0199591 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0199524 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0195356 |
| ANLN | anillin, actin binding protein | -0.0194281 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0192757 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0192422 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0191171 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0190868 |
| EGR1 | early growth response 1 | -0.0189494 |
| INSIG1 | insulin induced gene 1 | -0.0188251 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0186596 |
| HMGA1 | high mobility group AT-hook 1 | -0.0185833 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0185119 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0183748 |
| SUCO | SUN domain containing ossification factor | -0.0183694 |
| ARF4 | ADP-ribosylation factor 4 | -0.0183185 |
| MMP12 | matrix metallopeptidase 12 | -0.017752 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0175722 |
| PLIN2 | perilipin 2 | -0.0172154 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.016812 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | -0.0167729 |
| RPL31 | ribosomal protein L31 | -0.0167614 |
| DIAPH3 | diaphanous-related formin 3 | -0.0166879 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0166298 |
| COPA | coatomer protein complex, subunit alpha | -0.016512 |
| POTEF | POTE ankyrin domain family, member F | -0.0163483 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0162518 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0161999 |
| MORF4L2 | mortality factor 4 like 2 | -0.0161398 |
| NUP58 | nucleoporin 58 | -0.0160486 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0159774 |
| FAM162A | family with sequence similarity 162, member A | -0.0156604 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0156068 |
| TFG | TRK-fused gene | -0.015502 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0154729 |
| MKI67 | marker of proliferation Ki-67 | -0.0154611 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0152765 |
| HELZ | helicase with zinc finger | -0.0152717 |
| KIF4A | kinesin family member 4A | -0.0152158 |
| NREP | neuronal regeneration related protein | -0.014961 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0149517 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0148977 |
| ZNF292 | zinc finger protein 292 | -0.0148459 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0146483 |
| HMGB1 | high mobility group box 1 | -0.0144837 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0144237 |
| ECT2 | epithelial cell transforming 2 | -0.0143954 |
| IKBIP | IKBKB interacting protein | -0.0142689 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0142182 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0141594 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0140851 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0138691 |
| CALU | calumenin | -0.0137806 |
| AAK1 | AP2 associated kinase 1 | -0.0137396 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -0.0135798 |
| TTK | TTK protein kinase | -0.0134451 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0134295 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0134207 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0133323 |
| NDRG1 | N-myc downstream regulated 1 | -0.0132722 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0132481 |
| LRRC23 | leucine rich repeat containing 23 | -0.0132052 |
| ENO1 | enolase 1, (alpha) | -0.0130195 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -0.0129989 |
| ZNF148 | zinc finger protein 148 | -0.0129793 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0129325 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.012914 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0129064 |
| TMEM165 | transmembrane protein 165 | -0.0129016 |
