| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNA | filamin A, alpha | 0.123438 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0939582 |
| PLEC | plectin | 0.089142 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0815248 |
| PKM | pyruvate kinase, muscle | 0.0743254 |
| RNF213 | ring finger protein 213 | 0.0703769 |
| PLAT | plasminogen activator, tissue | 0.0680763 |
| SEPTIN9 | septin 9 | 0.0651967 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0616779 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0597077 |
| POTEF | POTE ankyrin domain family, member F | 0.0590912 |
| CTTN | cortactin | 0.0576632 |
| RPL3 | ribosomal protein L3 | 0.0568653 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0536246 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0533941 |
| MSN | moesin | 0.0532397 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0456634 |
| NAV2 | neuron navigator 2 | 0.0450264 |
| SFTPA2 | surfactant protein A2 | 0.0449284 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0445909 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0444477 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.043945 |
| RHOA | ras homolog family member A | 0.0436401 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0436242 |
| RUNX1 | runt-related transcription factor 1 | 0.043431 |
| MCL1 | myeloid cell leukemia 1 | 0.0427618 |
| AMOTL1 | angiomotin like 1 | 0.0423253 |
| ACTN1 | actinin, alpha 1 | 0.0418883 |
| SETD5 | SET domain containing 5 | 0.0418495 |
| FLNB | filamin B, beta | 0.0413211 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0409199 |
| NAV1 | neuron navigator 1 | 0.0408379 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0403766 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0403528 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0387788 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0387642 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.038547 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0379918 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0368906 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0367272 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0359478 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0356392 |
| CENPF | centromere protein F, 350/400kDa | 0.0355126 |
| SMAD3 | SMAD family member 3 | 0.0354883 |
| ANGPTL4 | angiopoietin-like 4 | 0.0354715 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0354487 |
| RPS4X | ribosomal protein S4, X-linked | 0.0349997 |
| RANGAP1 | Ran GTPase activating protein 1 | 0.03477 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0341548 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0340927 |
| EZR | ezrin | 0.0338526 |
| ANXA2 | annexin A2 | 0.0337663 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0336817 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0336374 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0336345 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0335118 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0332564 |
| HDAC4 | histone deacetylase 4 | 0.0327239 |
| DIAPH1 | diaphanous-related formin 1 | 0.0322173 |
| ADAR | adenosine deaminase, RNA-specific | 0.0321823 |
| ATXN1 | ataxin 1 | 0.0317928 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0316432 |
| TOB2 | transducer of ERBB2, 2 | 0.0313575 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0313481 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0313159 |
| CD44 | CD44 molecule (Indian blood group) | 0.0311968 |
| ACTG1 | actin gamma 1 | 0.0308195 |
| CCND1 | cyclin D1 | 0.0306872 |
| LAMB1 | laminin, beta 1 | 0.0303009 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0301547 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0301299 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0301254 |
| IPO7 | importin 7 | 0.0300452 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.029977 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.029873 |
| DST | dystonin | 0.0297121 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0296924 |
| H1-4 | H1.4 linker histone, cluster member | 0.0296787 |
| SP100 | SP100 nuclear antigen | 0.0295975 |
| LMNA | lamin A/C | 0.029434 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0293218 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0291606 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0290714 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0288682 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0286749 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0285088 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0284015 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0283022 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0280407 |
| FAM78B | family with sequence similarity 78, member B | 0.0277809 |
| RPS3 | ribosomal protein S3 | 0.027528 |
| WWOX | WW domain containing oxidoreductase | 0.0272201 |
| TPM3 | tropomyosin 3 | 0.0270661 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0266789 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0266397 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0265408 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0264109 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.026324 |
| ETV6 | ets variant 6 | 0.0260345 |
| ZC3H7B | zinc finger CCCH-type containing 7B | 0.0259281 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | -0.198031 |
| FN1 | fibronectin 1 | -0.183713 |
| LSAMP | limbic system-associated membrane protein | -0.132997 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.107707 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.100993 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0964648 |
| VIM | vimentin | -0.0838146 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0558881 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0536859 |
| CANX | calnexin | -0.0528974 |
| MT2A | metallothionein 2A | -0.0524272 |
| TNNC1 | troponin C type 1 (slow) | -0.0512881 |
| FRMD4A | FERM domain containing 4A | -0.047246 |
| CADM1 | cell adhesion molecule 1 | -0.043655 |
| MMP12 | matrix metallopeptidase 12 | -0.0389544 |
| TMSB10 | thymosin beta 10 | -0.0363612 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0358101 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0351426 |
| FMN1 | formin 1 | -0.0349098 |
| EHBP1 | EH domain binding protein 1 | -0.0325902 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -0.0321721 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.031109 |
| SBF2 | SET binding factor 2 | -0.0305198 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0301452 |
| INPP5F | inositol polyphosphate-5-phosphatase F | -0.0301264 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0300593 |
| RPL34 | ribosomal protein L34 | -0.0286407 |
| FHIT | fragile histidine triad | -0.0286122 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0275223 |
| FMNL2 | formin-like 2 | -0.0272774 |
| CLINT1 | clathrin interactor 1 | -0.0267762 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0265702 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0255658 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.025136 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0250359 |
| MT1X | metallothionein 1X | -0.0246938 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0245942 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0245034 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0240616 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0238029 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0235783 |
| TP63 | tumor protein p63 | -0.0234647 |
| JMJD1C | jumonji domain containing 1C | -0.023319 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0233125 |
| TFRC | transferrin receptor | -0.0230121 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0229626 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0226328 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0221796 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0221406 |
| NGLY1 | N-glycanase 1 | -0.0219924 |
| DIAPH2 | diaphanous-related formin 2 | -0.0219722 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.0217996 |
| RNF24 | ring finger protein 24 | -0.0217546 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0214924 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0212269 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0209899 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0208647 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0207464 |
| CNKSR3 | CNKSR family member 3 | -0.0203826 |
| NRG3 | neuregulin 3 | -0.0203735 |
| STAG2 | stromal antigen 2 | -0.0203338 |
| RNF130 | ring finger protein 130 | -0.0202088 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0201865 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.020103 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0200907 |
| COMMD10 | COMM domain containing 10 | -0.019517 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0194744 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0192836 |
| KPNB1 | karyopherin (importin) beta 1 | -0.019245 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0192439 |
| ZNF292 | zinc finger protein 292 | -0.0189571 |
| RPL30 | ribosomal protein L30 | -0.0187401 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0185819 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0184588 |
| NRN1 | neuritin 1 | -0.018406 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.018387 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0183434 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0181913 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.0181212 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0179327 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0178063 |
| CFDP1 | craniofacial development protein 1 | -0.0177797 |
| TRIM33 | tripartite motif containing 33 | -0.017734 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0175738 |
| CCDC47 | coiled-coil domain containing 47 | -0.0175014 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0174816 |
| ARFGEF3 | ARFGEF family member 3 | -0.0174502 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0174338 |
| FILIP1 | filamin A interacting protein 1 | -0.0173113 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.01731 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0172898 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0172862 |
| IFRD1 | interferon-related developmental regulator 1 | -0.017279 |
| RPL12 | ribosomal protein L12 | -0.0172243 |
| ABI1 | abl-interactor 1 | -0.0172041 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0171886 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0169543 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0168607 |
| NDRG1 | N-myc downstream regulated 1 | -0.0167434 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0166383 |
