| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.220271 |
| PKM | pyruvate kinase, muscle | 0.127337 |
| AHNAK | AHNAK nucleoprotein | 0.0989043 |
| RPL3 | ribosomal protein L3 | 0.0862242 |
| H1-4 | H1.4 linker histone, cluster member | 0.0858562 |
| EGFR | epidermal growth factor receptor | 0.0854405 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0852069 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0827791 |
| RHOA | ras homolog family member A | 0.0787752 |
| MACROD2 | MACRO domain containing 2 | 0.0728562 |
| MKI67 | marker of proliferation Ki-67 | 0.0727709 |
| MYO5C | myosin VC | 0.0717605 |
| VCL | vinculin | 0.0711605 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0668732 |
| TJP1 | tight junction protein 1 | 0.0658223 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0657401 |
| PDGFC | platelet derived growth factor C | 0.0655618 |
| LOC112694756 | uncharaterized LOC112694756 | 0.061124 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0559823 |
| EZR | ezrin | 0.0555966 |
| ZNF608 | zinc finger protein 608 | 0.0554707 |
| RRM2 | ribonucleotide reductase M2 | 0.0548441 |
| CENPF | centromere protein F, 350/400kDa | 0.053879 |
| PRELID2 | PRELI domain containing 2 | 0.0532146 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0527528 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0519495 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0512135 |
| TPX2 | TPX2, microtubule-associated | 0.0510679 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0510273 |
| NAV2 | neuron navigator 2 | 0.0490466 |
| ANXA1 | annexin A1 | 0.0473029 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0472099 |
| GSE1 | Gse1 coiled-coil protein | 0.0469701 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0467932 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0467838 |
| SEPTIN9 | septin 9 | 0.0464795 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0458672 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0456782 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0454257 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0427833 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0421719 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0405874 |
| DIAPH3 | diaphanous-related formin 3 | 0.0403599 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0397003 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0394795 |
| FER1L6 | fer-1-like family member 6 | 0.0384799 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0383488 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0377533 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0373368 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0365727 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0346801 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0342599 |
| CORO1C | coronin, actin binding protein, 1C | 0.0332428 |
| CREBBP | CREB binding protein | 0.0321818 |
| ANLN | anillin, actin binding protein | 0.0320969 |
| GLI2 | GLI family zinc finger 2 | 0.0316063 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0315264 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0308075 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0302037 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.030192 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0301784 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0301316 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0301156 |
| HJURP | Holliday junction recognition protein | 0.0299128 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0298541 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0289296 |
| TUBB4B | tubulin, beta 4B class IVb | 0.028689 |
| FLNB | filamin B, beta | 0.0280843 |
| CENPE | centromere protein E, 312kDa | 0.0279172 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0275215 |
| FLNA | filamin A, alpha | 0.0274229 |
| INTS6 | integrator complex subunit 6 | 0.0272547 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0269602 |
| H1-5 | H1.5 linker histone, cluster member | 0.0268924 |
| RPS12 | ribosomal protein S12 | 0.0268587 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0268482 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0268372 |
| MED13L | mediator complex subunit 13-like | 0.0267645 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0266161 |
| GLI3 | GLI family zinc finger 3 | 0.0264328 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0262345 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0260772 |
| ECT2 | epithelial cell transforming 2 | 0.0258921 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0258903 |
| EBNA1BP2 | EBNA1 binding protein 2 | 0.025647 |
| PCM1 | pericentriolar material 1 | 0.025608 |
| ITGA6 | integrin, alpha 6 | 0.0253212 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0249798 |
| RPS18 | ribosomal protein S18 | 0.0247311 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0246988 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0246739 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0241902 |
| TPM3 | tropomyosin 3 | 0.0241517 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.02414 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0239948 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0237471 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0236174 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0232931 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0232562 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0228126 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.121219 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.120515 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.113745 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.111794 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0964385 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0888022 |
| S100A6 | S100 calcium binding protein A6 | -0.078938 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.077745 |
| TXNRD1 | thioredoxin reductase 1 | -0.0757734 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0733648 |
| NBEA | neurobeachin | -0.0681355 |
| RPL35A | ribosomal protein L35a | -0.067808 |
| PTMA | prothymosin, alpha | -0.0660107 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0629941 |
| GOLGA4 | golgin A4 | -0.0617382 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0593545 |
| ANK2 | ankyrin 2, neuronal | -0.0547591 |
| RTN4 | reticulon 4 | -0.0543492 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.050401 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0498313 |
| GPHN | gephyrin | -0.0466766 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0453644 |
| RHBDD1 | rhomboid domain containing 1 | -0.0449531 |
| TMEM41B | transmembrane protein 41B | -0.0427638 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0401988 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0398985 |
| EXOC6B | exocyst complex component 6B | -0.0390037 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0387911 |
| RPL12 | ribosomal protein L12 | -0.0374498 |
| B2M | beta-2-microglobulin | -0.0374064 |
| RPLP1 | ribosomal protein, large, P1 | -0.0366866 |
| RPL13A | ribosomal protein L13a | -0.0361184 |
| JMJD1C | jumonji domain containing 1C | -0.035747 |
| RPS6 | ribosomal protein S6 | -0.0356576 |
| RPS19 | ribosomal protein S19 | -0.0352333 |
| RPS23 | ribosomal protein S23 | -0.0349862 |
| NEBL | nebulette | -0.0344187 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0343894 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0339925 |
| TMSB10 | thymosin beta 10 | -0.0323132 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0316729 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.03128 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0312231 |
| OSMR | oncostatin M receptor | -0.0312142 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0311395 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0310956 |
| COG5 | component of oligomeric golgi complex 5 | -0.0310041 |
| HMGA1 | high mobility group AT-hook 1 | -0.0302072 |
| RPL32 | ribosomal protein L32 | -0.0299434 |
| PHF14 | PHD finger protein 14 | -0.0298537 |
| DOCK3 | dedicator of cytokinesis 3 | -0.029148 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0289306 |
| RPL9 | ribosomal protein L9 | -0.028268 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0281328 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.027664 |
| WDR43 | WD repeat domain 43 | -0.0272475 |
| RPL11 | ribosomal protein L11 | -0.0272194 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0272015 |
| SMYD3 | SET and MYND domain containing 3 | -0.0268773 |
| TDRD3 | tudor domain containing 3 | -0.0262889 |
| DIAPH2 | diaphanous-related formin 2 | -0.0261937 |
| DENND1A | DENN/MADD domain containing 1A | -0.0258887 |
| RPL19 | ribosomal protein L19 | -0.0258316 |
| ATF4 | activating transcription factor 4 | -0.0256432 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0253927 |
| ZNF292 | zinc finger protein 292 | -0.0253137 |
| S100A9 | S100 calcium binding protein A9 | -0.0252781 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0251324 |
| PARD3 | par-3 family cell polarity regulator | -0.0250542 |
| VDAC1 | voltage-dependent anion channel 1 | -0.024944 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0247009 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.024632 |
| LDHA | lactate dehydrogenase A | -0.0243981 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | -0.0240109 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0239076 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0237179 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0234028 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0233449 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0230265 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.023025 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0229475 |
| RPS16 | ribosomal protein S16 | -0.0225514 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0223973 |
| TMEM263 | transmembrane protein 263 | -0.022257 |
| RPLP0 | ribosomal protein, large, P0 | -0.0221106 |
| RPS13 | ribosomal protein S13 | -0.0219235 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0213969 |
| AHI1 | Abelson helper integration site 1 | -0.0213034 |
| PLCE1 | phospholipase C, epsilon 1 | -0.0212566 |
| THOC2 | THO complex 2 | -0.0212055 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0210551 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0208311 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0208152 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0208095 |
| ETNK1 | ethanolamine kinase 1 | -0.0207112 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.020683 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0206097 |
| ALDOC | aldolase C, fructose-bisphosphate | -0.0205494 |
| METTL15 | methyltransferase like 15 | -0.0204938 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0204617 |
