| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lidocaine (hydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.132915 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.119052 |
| FRMD4A | FERM domain containing 4A | 0.114844 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.111866 |
| BICC1 | BicC family RNA binding protein 1 | 0.10921 |
| HDAC9 | histone deacetylase 9 | 0.10596 |
| SMAD3 | SMAD family member 3 | 0.100953 |
| GLIS3 | GLIS family zinc finger 3 | 0.0989033 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0971805 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0953606 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0928279 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0896569 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0807392 |
| HMGA2 | high mobility group AT-hook 2 | 0.0800523 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0739361 |
| FLNA | filamin A, alpha | 0.072273 |
| CD44 | CD44 molecule (Indian blood group) | 0.0681431 |
| NAV1 | neuron navigator 1 | 0.0663586 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0644856 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.063565 |
| ATXN1 | ataxin 1 | 0.0608741 |
| GPC6 | glypican 6 | 0.0600122 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0599159 |
| VCL | vinculin | 0.0578607 |
| NAV2 | neuron navigator 2 | 0.0575731 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0575442 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0563801 |
| VCAN | versican | 0.0556028 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0538318 |
| VEGFA | vascular endothelial growth factor A | 0.0509981 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0508278 |
| TNS3 | tensin 3 | 0.0505007 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0500137 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0468401 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0461367 |
| CD59 | CD59 molecule, complement regulatory protein | 0.043908 |
| SVIL | supervillin | 0.0438792 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0435293 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.04272 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0424937 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0423024 |
| MSN | moesin | 0.0421043 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0419845 |
| FLNB | filamin B, beta | 0.0413645 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0411559 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0398434 |
| PLPP4 | phospholipid phosphatase 4 | 0.0392147 |
| RPS4X | ribosomal protein S4, X-linked | 0.0391008 |
| MYOF | myoferlin | 0.0390726 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0379662 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0371512 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0369859 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0367049 |
| KYNU | kynureninase | 0.036639 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0356243 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0352657 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0348033 |
| CENPF | centromere protein F, 350/400kDa | 0.0344443 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0343775 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0343667 |
| SEPTIN9 | septin 9 | 0.0342274 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0339647 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0338604 |
| ABHD12 | abhydrolase domain containing 12 | 0.0329241 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0326725 |
| RNF213 | ring finger protein 213 | 0.0321875 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0319023 |
| TGM2 | transglutaminase 2 | 0.0318197 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0315821 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0314984 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0314658 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0312625 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0312237 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0311194 |
| RASAL2 | RAS protein activator like 2 | 0.0308644 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0305998 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0305708 |
| MCL1 | myeloid cell leukemia 1 | 0.0303106 |
| RUNX1 | runt-related transcription factor 1 | 0.0301495 |
| BPTF | bromodomain PHD finger transcription factor | 0.0299122 |
| FMN1 | formin 1 | 0.0295146 |
| SFTPA2 | surfactant protein A2 | 0.0294493 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0293945 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0292317 |
| SYNJ2 | synaptojanin 2 | 0.0292125 |
| ACTN1 | actinin, alpha 1 | 0.0290114 |
| LDHA | lactate dehydrogenase A | 0.0289201 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.02885 |
| JMJD1C | jumonji domain containing 1C | 0.0284424 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0284263 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0284218 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0278945 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0278112 |
| MED13L | mediator complex subunit 13-like | 0.0277908 |
| ANXA2 | annexin A2 | 0.0277406 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0277041 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0275977 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0275459 |
| TPM1 | tropomyosin 1 (alpha) | 0.0267292 |
| DUSP10 | dual specificity phosphatase 10 | 0.0265739 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.129432 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.121546 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0622293 |
| MT2A | metallothionein 2A | -0.0592737 |
| CANX | calnexin | -0.0531556 |
| PTMA | prothymosin, alpha | -0.0521558 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0475502 |
| IER3 | immediate early response 3 | -0.0453218 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0422929 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0417649 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0367044 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0365128 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0360653 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0325435 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0312674 |
| GOLGA4 | golgin A4 | -0.0311566 |
| ADM | adrenomedullin | -0.0310748 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0308702 |
| HLA-E | major histocompatibility complex, class I, E | -0.0299118 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0291207 |
| HLA-B | major histocompatibility complex, class I, B | -0.0289537 |
| PDE10A | phosphodiesterase 10A | -0.0278094 |
| NGLY1 | N-glycanase 1 | -0.0276677 |
| OGA | O-GlcNAcase | -0.0265393 |
| GDF15 | growth differentiation factor 15 | -0.0255715 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0252266 |
| TMSB10 | thymosin beta 10 | -0.0251632 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0249502 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.0248281 |
| ZNF292 | zinc finger protein 292 | -0.0245018 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0241364 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0238741 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0237319 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0236395 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0233617 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0233164 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0230304 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0223092 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.022276 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.021707 |
| RPS13 | ribosomal protein S13 | -0.0216394 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0214227 |
| NDRG1 | N-myc downstream regulated 1 | -0.0214009 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0212105 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0208735 |
| MMP12 | matrix metallopeptidase 12 | -0.0208508 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0206572 |
| FTL | ferritin, light polypeptide | -0.0205706 |
| TMSB4X | thymosin beta 4, X-linked | -0.0205213 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0199701 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.019907 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0198909 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0197413 |
| RPS3 | ribosomal protein S3 | -0.0196482 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0195046 |
| RPL36A | ribosomal protein L36a | -0.0180487 |
| RPL34 | ribosomal protein L34 | -0.0179612 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0177715 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | -0.0174139 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.017218 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0169114 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0167724 |
| RPS29 | ribosomal protein S29 | -0.0166699 |
| RPS27A | ribosomal protein S27a | -0.0166681 |
| RTN3 | reticulon 3 | -0.0165707 |
| USP37 | ubiquitin specific peptidase 37 | -0.0165543 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 | -0.0165253 |
| RPL37A | ribosomal protein L37a | -0.0163115 |
| RAI14 | retinoic acid induced 14 | -0.0163091 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0161875 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0160842 |
| SDCBP | syndecan binding protein (syntenin) | -0.0160502 |
| FAM162A | family with sequence similarity 162, member A | -0.0159979 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0159641 |
| RPS6 | ribosomal protein S6 | -0.0159013 |
| TCEAL9 | transcription elongation factor A like 9 | -0.015393 |
| HLA-A | major histocompatibility complex, class I, A | -0.0149078 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0145983 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0145825 |
| RLF | rearranged L-myc fusion | -0.0145747 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0145483 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0145363 |
| ARFGEF3 | ARFGEF family member 3 | -0.0143093 |
| RPL36 | ribosomal protein L36 | -0.0141632 |
| FOXO3 | forkhead box O3 | -0.0141043 |
| RPS15 | ribosomal protein S15 | -0.014018 |
| CEP95 | centrosomal protein 95kDa | -0.0140026 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0139546 |
| RND3 | Rho family GTPase 3 | -0.0139058 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0138747 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0138086 |
| CADM1 | cell adhesion molecule 1 | -0.0138 |
| USP53 | ubiquitin specific peptidase 53 | -0.0136807 |
| RPL35A | ribosomal protein L35a | -0.0135883 |
| HM13 | histocompatibility (minor) 13 | -0.0132701 |
| THBS2 | thrombospondin 2 | -0.0131266 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.0131006 |
| TBCA | tubulin folding cofactor A | -0.0128667 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0128032 |
| PGM3 | phosphoglucomutase 3 | -0.0127563 |
