| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.191614 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.169839 |
| CD44 | CD44 molecule (Indian blood group) | 0.0945826 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0894857 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0785093 |
| FN1 | fibronectin 1 | 0.0778786 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0745987 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0731082 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0679076 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0661916 |
| AHNAK | AHNAK nucleoprotein | 0.0658181 |
| HIP1 | huntingtin interacting protein 1 | 0.0657437 |
| FLNA | filamin A, alpha | 0.0646866 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0624518 |
| HMGA2 | high mobility group AT-hook 2 | 0.060965 |
| STC1 | stanniocalcin 1 | 0.0599947 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0595576 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0588418 |
| UBC | ubiquitin C | 0.0578506 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.056405 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0548409 |
| PLEC | plectin | 0.0545018 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0536614 |
| NAV1 | neuron navigator 1 | 0.0532856 |
| MYO10 | myosin X | 0.0531974 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0531347 |
| SDC4 | syndecan 4 | 0.0529544 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0510101 |
| PRSS23 | protease, serine, 23 | 0.0498336 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0497151 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0482494 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0469859 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0466439 |
| FAM20C | family with sequence similarity 20, member C | 0.0464402 |
| MT1X | metallothionein 1X | 0.0462548 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0451863 |
| SMAD3 | SMAD family member 3 | 0.0446324 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0444187 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0437996 |
| KYNU | kynureninase | 0.0432227 |
| ENO1 | enolase 1, (alpha) | 0.04259 |
| RUNX1 | runt-related transcription factor 1 | 0.0425293 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0423469 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.041984 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.041924 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0416466 |
| NAV2 | neuron navigator 2 | 0.0404413 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0398736 |
| ECE1 | endothelin converting enzyme 1 | 0.0392543 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0377469 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0376602 |
| MRTFA | myocardin related transcription factor A | 0.0371309 |
| GLIS3 | GLIS family zinc finger 3 | 0.0370782 |
| GSE1 | Gse1 coiled-coil protein | 0.0369008 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0366991 |
| COL5A1 | collagen, type V, alpha 1 | 0.0366087 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0360493 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0359403 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0352967 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0351544 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0351007 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0350979 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0345642 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0343187 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0340069 |
| RPL3 | ribosomal protein L3 | 0.0335662 |
| PRELID2 | PRELI domain containing 2 | 0.0335074 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0334156 |
| USP34 | ubiquitin specific peptidase 34 | 0.0331083 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0329155 |
| SEPTIN9 | septin 9 | 0.0327937 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0327429 |
| BPTF | bromodomain PHD finger transcription factor | 0.0327325 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0321252 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0317922 |
| HDLBP | high density lipoprotein binding protein | 0.0317902 |
| TAPBP | TAP binding protein (tapasin) | 0.0317229 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0315846 |
| ATXN1 | ataxin 1 | 0.0315755 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0313171 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0307432 |
| MT2A | metallothionein 2A | 0.0306951 |
| TMSB4X | thymosin beta 4, X-linked | 0.0305565 |
| MAP1B | microtubule-associated protein 1B | 0.0303874 |
| TNS3 | tensin 3 | 0.0303486 |
| RPL15 | ribosomal protein L15 | 0.0302027 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0300456 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0297848 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0296383 |
| MCL1 | myeloid cell leukemia 1 | 0.0296298 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0290619 |
| LDHA | lactate dehydrogenase A | 0.0290421 |
| RPL37A | ribosomal protein L37a | 0.0287443 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.028698 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0285342 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0285019 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0284392 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0281225 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0277883 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0277275 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.205118 |
| TMSB10 | thymosin beta 10 | -0.13412 |
| FTL | ferritin, light polypeptide | -0.0930578 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.092061 |
| HLA-B | major histocompatibility complex, class I, B | -0.0662133 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0653281 |
| COL1A2 | collagen, type I, alpha 2 | -0.0640899 |
| VIM | vimentin | -0.0595439 |
| COL1A1 | collagen, type I, alpha 1 | -0.0592677 |
| CANX | calnexin | -0.0579031 |
| TMEM165 | transmembrane protein 165 | -0.0562222 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.052019 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0489565 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0484955 |
| B2M | beta-2-microglobulin | -0.0457578 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0456271 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0408953 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0406846 |
| RPL35A | ribosomal protein L35a | -0.0385058 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0380871 |
| S100A9 | S100 calcium binding protein A9 | -0.0339108 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0331729 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0325579 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0314297 |
| SRP54 | signal recognition particle 54kDa | -0.0313544 |
| COL3A1 | collagen, type III, alpha 1 | -0.0312444 |
| GOLGA4 | golgin A4 | -0.0298156 |
| LOXL2 | lysyl oxidase-like 2 | -0.0296954 |
| COL5A2 | collagen, type V, alpha 2 | -0.0296589 |
| RNF145 | ring finger protein 145 | -0.0292882 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0284497 |
| RPS23 | ribosomal protein S23 | -0.0279467 |
| TMEM263 | transmembrane protein 263 | -0.0278902 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0274667 |
| RPLP1 | ribosomal protein, large, P1 | -0.0268308 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.026532 |
| PGK1 | phosphoglycerate kinase 1 | -0.026003 |
| RPS6 | ribosomal protein S6 | -0.0249423 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0247165 |
| RPS19 | ribosomal protein S19 | -0.0243325 |
| HLA-C | major histocompatibility complex, class I, C | -0.0237481 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0233952 |
| RTN4 | reticulon 4 | -0.0232185 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0228571 |
| CDH13 | cadherin 13 | -0.0226493 |
| CADM1 | cell adhesion molecule 1 | -0.0225034 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0225018 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0224978 |
| FAM13A | family with sequence similarity 13, member A | -0.0218517 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.0217346 |
| PLCB4 | phospholipase C, beta 4 | -0.0217042 |
| CERT1 | ceramide transporter 1 | -0.0214409 |
| COG5 | component of oligomeric golgi complex 5 | -0.0214285 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.021357 |
| TPM4 | tropomyosin 4 | -0.0212812 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0211927 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0211282 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0211226 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0210554 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | -0.0209607 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | -0.0207807 |
| ARF4 | ADP-ribosylation factor 4 | -0.0207739 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0203346 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0202814 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0202535 |
| IKBIP | IKBKB interacting protein | -0.020081 |
| WASF2 | WAS protein family, member 2 | -0.0199127 |
| DSTN | destrin (actin depolymerizing factor) | -0.0198123 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0195642 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0194606 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0192016 |
| PGM3 | phosphoglucomutase 3 | -0.0190426 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0188611 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0187728 |
| RPL34 | ribosomal protein L34 | -0.0186494 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0185538 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0185513 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.018436 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0183512 |
| DTNA | dystrobrevin, alpha | -0.018332 |
| MYADM | myeloid-associated differentiation marker | -0.0183092 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0181603 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0180325 |
| EGR1 | early growth response 1 | -0.0180064 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0179898 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0179348 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0179322 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | -0.0178806 |
| MAGT1 | magnesium transporter 1 | -0.0178666 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0177973 |
| UBAC2 | UBA domain containing 2 | -0.0177955 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0176833 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0175952 |
| CDC27 | cell division cycle 27 | -0.0175907 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.0175153 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0173405 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0172974 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0172271 |
| HLA-A | major histocompatibility complex, class I, A | -0.0171732 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0171069 |
