| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lidocaine (hydrochloride) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lidocaine (hydrochloride)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOC112694756 | uncharaterized LOC112694756 | 0.11534 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.10112 |
| SMAD3 | SMAD family member 3 | 0.0891717 |
| SMYD3 | SET and MYND domain containing 3 | 0.0820412 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0805173 |
| HMGA2 | high mobility group AT-hook 2 | 0.0716381 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0714984 |
| CD44 | CD44 molecule (Indian blood group) | 0.0701832 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.066253 |
| DST | dystonin | 0.0625397 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0613464 |
| PKM | pyruvate kinase, muscle | 0.0611579 |
| AHNAK | AHNAK nucleoprotein | 0.0601959 |
| SVIL | supervillin | 0.0582626 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0569036 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0539444 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0537719 |
| PRELID2 | PRELI domain containing 2 | 0.0527549 |
| FLNA | filamin A, alpha | 0.0525181 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0518819 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0503982 |
| PLEC | plectin | 0.0495506 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0494419 |
| ANO6 | anoctamin 6 | 0.048294 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0482682 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0479426 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0476469 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0471414 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0460595 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.045639 |
| ERBIN | erbb2 interacting protein | 0.0452233 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0439693 |
| MCL1 | myeloid cell leukemia 1 | 0.0438086 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0434436 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0427132 |
| RAD51B | RAD51 paralog B | 0.0422152 |
| MSN | moesin | 0.0418292 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0416094 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0415001 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0414465 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.04064 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0396671 |
| INTS6 | integrator complex subunit 6 | 0.0393249 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0388759 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0384062 |
| PTK2 | protein tyrosine kinase 2 | 0.0381791 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0379605 |
| H1-4 | H1.4 linker histone, cluster member | 0.0375466 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0373101 |
| EFNA5 | ephrin-A5 | 0.0369396 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0365628 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0361879 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0360913 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0360278 |
| FMNL2 | formin-like 2 | 0.0358111 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0357719 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0353992 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0348844 |
| CEP250 | centrosomal protein 250kDa | 0.0348693 |
| PDE8A | phosphodiesterase 8A | 0.0341849 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0336804 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0336169 |
| TPI1 | triosephosphate isomerase 1 | 0.033549 |
| IL6ST | interleukin 6 signal transducer | 0.0334011 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0332732 |
| ANGPTL4 | angiopoietin-like 4 | 0.0327135 |
| RUNX1 | runt-related transcription factor 1 | 0.0326844 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0321425 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0319025 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0318673 |
| UTRN | utrophin | 0.0317751 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0317072 |
| FLNB | filamin B, beta | 0.0310696 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0308049 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0308025 |
| AEBP2 | AE binding protein 2 | 0.0307332 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0304878 |
| PRSS23 | protease, serine, 23 | 0.0301322 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0298132 |
| POTEF | POTE ankyrin domain family, member F | 0.029263 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0291549 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0291344 |
| TJP1 | tight junction protein 1 | 0.0289828 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0283452 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0279637 |
| EXOC4 | exocyst complex component 4 | 0.0277832 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0277606 |
| TGM2 | transglutaminase 2 | 0.0275783 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0275227 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0274741 |
| JAK1 | Janus kinase 1 | 0.0273319 |
| CNKSR3 | CNKSR family member 3 | 0.0272687 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0272292 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0270676 |
| ACTN1 | actinin, alpha 1 | 0.0269077 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0268972 |
| FARS2 | phenylalanyl-tRNA synthetase 2, mitochondrial | 0.0267231 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0267159 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0265534 |
| WWOX | WW domain containing oxidoreductase | 0.0263602 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.16392 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.147916 |
| PTMA | prothymosin, alpha | -0.102044 |
| TMSB10 | thymosin beta 10 | -0.0979104 |
| VIM | vimentin | -0.0964918 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0686821 |
| NDRG1 | N-myc downstream regulated 1 | -0.0526464 |
| IGF2 | insulin-like growth factor 2 | -0.0496507 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0486323 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0472241 |
| CANX | calnexin | -0.0375306 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0372119 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0337269 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0335061 |
| RPL35A | ribosomal protein L35a | -0.0334558 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0325492 |
| IER3 | immediate early response 3 | -0.0323515 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0292681 |
| ATXN1 | ataxin 1 | -0.0291324 |
| RPL31 | ribosomal protein L31 | -0.028626 |
| SEPTIN7 | septin 7 | -0.0279664 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0278192 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.026497 |
| RPLP1 | ribosomal protein, large, P1 | -0.026382 |
| NUP58 | nucleoporin 58 | -0.026321 |
| RPS6 | ribosomal protein S6 | -0.0262033 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0255389 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0248225 |
| HLA-B | major histocompatibility complex, class I, B | -0.0244476 |
| NLRP1 | NLR family, pyrin domain containing 1 | -0.0244342 |
| RRBP1 | ribosome binding protein 1 | -0.0242579 |
| SGO2 | shugoshin 2 | -0.0241854 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0236337 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.023501 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0233972 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.022836 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0227931 |
| RPS8 | ribosomal protein S8 | -0.0226375 |
| RPL34 | ribosomal protein L34 | -0.02236 |
| USP15 | ubiquitin specific peptidase 15 | -0.0223283 |
| RPL23 | ribosomal protein L23 | -0.0221744 |
| BSG | basigin (Ok blood group) | -0.0221259 |
| INSIG1 | insulin induced gene 1 | -0.0219681 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0217432 |
| RPS3 | ribosomal protein S3 | -0.0216997 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.02153 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0215184 |
| ZNF292 | zinc finger protein 292 | -0.0214778 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0214735 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0212453 |
| RSF1 | remodeling and spacing factor 1 | -0.0209368 |
| ANLN | anillin, actin binding protein | -0.0208557 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0207581 |
| WDR45B | WD repeat domain 45B | -0.0206814 |
| TMEM263 | transmembrane protein 263 | -0.0206584 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0206466 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0206166 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0205956 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0205316 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0203666 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0203646 |
| TMEM123 | transmembrane protein 123 | -0.0200356 |
| RPL12 | ribosomal protein L12 | -0.019998 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0198672 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0198239 |
| RPL15 | ribosomal protein L15 | -0.0195836 |
| MEF2A | myocyte enhancer factor 2A | -0.0194225 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.019375 |
| STK4 | serine/threonine kinase 4 | -0.0193515 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0193382 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0190643 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0189124 |
| PYGL | phosphorylase, glycogen, liver | -0.018755 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0186988 |
| GPR107 | G protein-coupled receptor 107 | -0.0186721 |
| PFN1 | profilin 1 | -0.0185551 |
| TTK | TTK protein kinase | -0.018548 |
| FTL | ferritin, light polypeptide | -0.0184338 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0183735 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0182073 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | -0.0181576 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0181469 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0181158 |
| GPC6 | glypican 6 | -0.0181096 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0180068 |
| FAM3C | family with sequence similarity 3, member C | -0.0179733 |
| NGLY1 | N-glycanase 1 | -0.0178601 |
| MAP1B | microtubule-associated protein 1B | -0.0178341 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0178273 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0176284 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0174123 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0172862 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.0172273 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0172048 |
| NPR2 | natriuretic peptide receptor 2 | -0.0171205 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0167957 |
| HMGA1 | high mobility group AT-hook 1 | -0.0167911 |
| SNX3 | sorting nexin 3 | -0.0167313 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0167065 |
| RPL36 | ribosomal protein L36 | -0.0164931 |
